Internal Seminars – Team Simona Saccani & Team Barbara Seitz-Polski
For more information, please refer to your emails
For more information, please refer to your emails
Hematopoietic stem cells (HSCs) are pluripotent cells that have capacity to replenish all blood cells. HSCs stay quiescent| in the bone marrow niche, until they get triggered to differentiate, which is also happening during aging. However, whether aging is a collection of moments of stress signals that make HSCs exit quiescence is not known. Here, […]
Abstract: Cellular senescence is conventionally defined as a state of permanent cell cycle arrest in response to multiple stress factors such as DNA damage but also aging. Excessive accumulation of senescent cells can negatively impact different tissues, creating a proinflammatory environment leading to development of various age-related diseases. This project is focus on the analysis […]