• A novel bioinformatic approach reveals cooperation between Cancer/Testis genes in basal-like breast tumors.

    Laisné M, Rodgers B, Benlamara S, Wicinski J, Nicolas A, Djerroudi L, Gupta N, Ferry L, Kirsh O, Daher D, Philippe C, Okada Y, Charafe-Jauffret E, Cristofari G, Meseure D, Vincent-Salomon A, Ginestier C, Defossez PA.

    Oncogene. 2024 Mar 11. doi: 10.1038/s41388-024-03002-7.

    PMID: 38467851

  • Snapshots of genetic copy-and-paste machinery in action.

    Cristofari G.

    Nature. 2024 Feb;626(7997):40-42. doi: 10.1038/d41586-024-00112-w.

    PMID: 38287184

  • Locus-level L1 DNA methylation profiling reveals the epigenetic and transcriptional interplay between L1s and their integration sites.

    Lanciano S, Philippe C, Sarkar A, Pratella D, Domrane C, Doucet AJ, van Essen D, Saccani S, Ferry L, Defossez PA, Cristofari G.

    Cell Genom. 2024 Feb 14;4(2):100498. doi: 10.1016/j.xgen.2024.100498.

    PMID: 38309261 PMCID: PMC10879037 HAL: hal-04462176

  • Cancer Immunotherapy: How to Exploit Transposable Elements?

    Lanciano S, Cristofari G.

    Clin Chem. 2024 Jan 4;70(1):17-20.

    doi: 10.1093/clinchem/hvad091; PMID: 37572000; HAL: inserm-04180892

  • Ancient and recent origins of shared polymorphisms in yeast

    Tellini N, De Chiara M, Mozzachiodi S, Tattini L, Vischioni C, Naumova ES, Warringer J, Bergström A, Liti G@

    Nature Ecology & Evolution

    2024 Mar 12. doi: 10.1038/s41559-024-02352-5. Online ahead of print.

    PMID: 38472432

  • Disparate genetic divergence patterns in three corals across a pan-Pacific environmental gradient highlight species-specific adaptation

    Christian R. Voolstra, Benjamin C. C. Hume, Eric J. Armstrong, Guinther Mitushasi, Barbara Porro, Nicolas Oury, Sylvain Agostini, Emilie Boissin, Julie Poulain, Quentin Carradec, David A. Paz-García, Didier Zoccola, Hélène Magalon, Clémentine Moulin, Guillaume Bourdin, Guillaume Iwankow, Sarah Romac, Bernard Banaigs, Emmanuel Boss, Chris Bowler, Colomban de Vargas, Eric Douville, Michel Flores, Paola Furla, Pierre E. Galand, Eric Gilson, Fabien Lombard, Stéphane Pesant, Stéphanie Reynaud, Matthew B. Sullivan, Shinichi Sunagawa, Olivier P. Thomas, Romain Troublé, Rebecca Vega Thurber, Patrick Wincker, Serge Planes, Denis Allemand & Didier Forcioli 

    npj Biodiversity, 2, 15 (2023)

    PMID: npj Biodiversity

  • Chapter 30: Phylum Hemichordata

    Röttinger E & Osborn K J

    Atlas of Marine Invertebrate Larvae, in press.

    Editors: Young Craig M., Sewell Mary A., Boyle Michael J. Academic Press, Elsevier, Cambridge (USA)


  • Embracing the diversity of model systems to deconstruct the basis of regeneration and tissue repair

    Amiel AR, Tsai SL, Wehner D. 

    Development, 150 (3): dev201579

    PMID: 36718794

  • Open science resources from the Tara Pacific expedition across coral reef and surface ocean ecosystems

    Lombard F, Bourdin G, Pesant S, Agostini S, Baudena A, Boissin E, Cassar N, Clampitt M,  Conan P, Da Silva O,  Dimier C, Douville E,  Elineau A,  Fin J, Flores M, Ghiglione J, Hume B, Jalabert L, John S, Kelly R, Koren I, Lin Y,  Marie D, McMinds R, Mériguet Z, Metzl N, Paz-García D, Pedrotti M, Poulain J, Pujo-Pay M, Ras J,  Reverdin G, Romac S, Rouan A, Röttinger E, Vardi A, Voolstra C, Moulin C, Iwankow G, Banaigs B, Bowler C, de Vargas C, Forcioli D, Furla P, Galand P, Gilson E, Reynaud S, Sunagawa S, Sullivan M, Thomas O, Trouble R, Vega Thurber R, Wincker P, Zoccola D, Allemand D, Planes S, Boss E, Gorsky G.

    Scientific Data,10 (324)

    PMID: 37264023

  • Telomere DNA length regulation is influenced by seasonal temperatures differences in short-lived but not in long- lived reef-building corals

    Rouan A, Pousse M, Djerbi N, Porro B, Bourdin G, Carradec Q, Hume BCC, Poulain J,Le-Hoang J, Armstrong E, Agostini S, Die Morini L, Leone C, Wurzer L, Tran J, McMinds R, A. Paz-García D, Giraud-Panis MJ, Deshuraud R, Ottaviani A, Zoccola D, Pey A,  Moulin C, Boissin E, Iwankow G, Poulain J,  Romac S, Tara Pacific Consortium Coordinators, Planes S, Allemand D, Pesant S, Wincker P, Röttinger E, Furla P, Voolstra CR, Forcioli D, Lombard F and Gilson E

    Nature Communications, 1;14(1):3038

    PMID: 37263999

  • N-terminal alanine-rich (NTAR) sequences drive precise start codon selection resulting in elevated translation of multiple proteins including ERK1/2.

    Initiation of translation is essential for protein synthesis. A crucial step is the correct choice of the start AUG, which leads to the production of the fully functional polypeptide. To date, nucleotide composition next to the AUG has been considered the only determinant of start codon selection. Our work identifies a large family of proteins whose start codon choice is determined by an N-terminal alanine-rich sequence (NTAR) that enables efficient protein translation. Many of these proteins are encoded by housekeeping genes. Among them, the NTARs of the pivotal kinases ERK1 and ERK2 are highly optimized in humans, shaping ERK signal transduction by increasing the kinase quantity. Our findings could be useful for applied biology, especially for mRNA-based therapeutics.


  • Telomere DNA length regulation is influenced by seasonal temperature differences in short-lived but not in long-lived reef-building corals

    Rouan A, Pousse M, Djerbi N, Porro B, Bourdin G, Carradec Q, Hume BCC, Poulain J,Le-Hoang J, Armstrong E, Agostini S, Die Morini L, Leone C, Wurzer L, Tran J, McMinds R, A. Paz-García D, Giraud-Panis MJ, Deshuraud R, Ottaviani A, Zoccola D, Pey A,  Moulin C, Boissin E, Iwankow G, Poulain J,  Romac S, Tara Pacific Consortium Coordinators, Planes S, Allemand D, Pesant S, Wincker P, Röttinger E, Furla P, Voolstra CR, Forcioli D, Lombard F and Gilson E

    Nature Communications, 1;14(1):3038

    PMID: 37263999

  • Telomere-to-telomere assemblies of 142 strains characterize the genome structural landscape in Saccharomyces cerevisiae

    O'Donnell S*, Yue JX*, Saada OA, Agier N, Caradec C, Cokelaer T, De Chiara M, Delmas S, Dutreux F, Fournier T, Friedrich A, Kornobis E, Li J, Miao Z, Tattini L, Schacherer J@, Liti G@, Fischer G@.
    Nature Genetics. 2023 Jul 31.

    doi: 10.1038/s41588-023-01459-y.

    PMID: 37524789

  • Genome-Wide Young L1 Methylation Profiling by bs-ATLAS-seq.

    Philippe C*, Cristofari G*. [*co-corresponding authors]

    Methods Mol Biol. 2023;2607:127-150. doi: 10.1007/978-1-0716-2883-6_8.

    PMID: 36449162

  • Targeted Nanopore Resequencing and Methylation Analysis of LINE-1 Retrotransposons.

    Sarkar A*, Lanciano S*, Cristofari G. [*co-first authors]

    Methods Mol Biol. 2023;2607:173-198. doi: 10.1007/978-1-0716-2883-6_10.

    PMID: 36449164 bioRxiv: 2022.06.25.497594

  • Precise and Scarless Insertion of Transposable Elements by Cas9-Mediated Genome Engineering.

    Weber VM, Doucet AJ*, Cristofari G*. [*co-last authors]

    Methods Mol Biol. 2023;2607:329-353. doi: 10.1007/978-1-0716-2883-6_15.

    PMID: 36449169

  • A genome-wide screen reveals new regulators of the 2-cell-like cell state.

    Gupta N, Yakhou L, Albert JR, Azogui A, Ferry L, Kirsh O, Miura F, Battault S, Yamaguchi K, Laisné M, Domrane C, Bonhomme F, Sarkar A, Delagrange M, Ducos B, Cristofari G, Ito T, Greenberg MVC, Defossez PA.

    Nat Struct Mol Biol. 2023 Aug;30(8):1105-1118. doi: 10.1038/s41594-023-01038-z

    PMID: 37488355

  • Noninvasive and Multicancer Biomarkers: The Promise of LINE-1 Retrotransposons.

    Doucet AJ, Cristofari G.

    Cancer Discov. 2023 Dec 12;13(12):2502-2504. doi: 10.1158/2159-8290.CD-23-1063.

    PMID: 38084092 HAL: inserm-04342008

  • Different environmental response strategies in sympatric corals from Pacific Islands

    Porro B, Zamoum T, Forcioli D, Gilson E, Poquet A, Di Franco E, Barnay-Verdier S, Lombard F, Voolstra CR, Hume BCC, Galand PE,  Moulin C, Boissin E, Bourdin G,  Iwankow G, Poulain J, Sarah Romac S,  Agostini S, Banaigs B, Emmanuel Boss 14, Chris Bowler 8,18, Colomban de Vargas16, Eric Douville E, Flores M,  Pesant S, Reynaud S, Sullivan MB, Sunagawa S, Thomas OP,  Troublé R,  Vega Thurber R, Wincker P, Zoccola D, Planes S, Allemand D, Röttinger E & Furla P

    Communications Earth & Environment 4:311 

    PMID: cee

  • A genetic screen identifies BEND3 as a regulator of bivalent gene expression and global DNA methylation.

    Yakhou L, Azogui A, Gupta N, Richard Albert J, Miura F, Ferry L, Yamaguchi K, Battault S, Therizols P, Bonhomme F, Bethuel E, Sarkar A, Greenberg MVC, Arimondo PB, Cristofari G, Kirsh O, Ito T, Defossez PA.

    Nucleic Acids Res. 2023 Oct 27;51(19):10292-10308. doi: 10.1093/nar/gkad719.

    PMID: 37650637 PMCID: PMC10602864

  • Domestication reprogrammed the budding yeast life cycle

    De Chiara M, Barré BP, Persson K, Irizar A, Vischioni C, Khaiwal S, Stenberg S, Amadi OC, Žun G, Doberšek K, Taccioli C, Schacherer J, Petrovič U, Warringer J, Liti G.
    Nature Ecology & Evolution. doi: 10.1038/s41559-022-01671-9.
    PMID: 35210580

  • Multilayer omics analysis reveals a non-classical retinoic acid signaling axis that regulates hematopoietic stem cell identity.

    PMID 34706256

  • Guidelines for creating a user-friendly and open-access gene expression database for comparing embryonic development and regeneration in Nematostella vectensis

    Olivier Croce & Röttinger E

    Methods in Molecular Biology. Editor: Brigitte Galliot & Simon Blanchoud, 2022;2450:649-662

    PMID: 35359334




  • Articulating the “stem cell niche” paradigm through the lens of non-model aquatic invertebrates

    Martinez P, Ballarin L, Ereskovsky A, Gazave E, Hobmayer B, Manni L, Röttinger E, Sprecher GS, Tiozzo S, Varela-Coelho A, Rinkevich B

    BMC Biology, Jan 20, 20:23

    PMID: 35057814

  • TASOR epigenetic repressor cooperates with a CNOT1 RNA degradation pathway to repress HIV.

    Matkovic R, Morel M, Lanciano S, Larrous P, Martin B, Bejjani F, Vauthier V, Hansen MMK, Emiliani S, Cristofari G, Gallois-Montbrun S, Margottin-Goguet F.

    Nat Commun. 2022 Jan 10;13(1):66. doi: 10.1038/s41467-021-27650-5

    PMID: 35013187

  • Telomerase is required for glomerular renewal in kidneys of adult mice

    Montandon M, Hamidouche T, Yart L, Duret LC, Pons C, Soubeiran N, Pousse M, Cervera L, Vial V, Fassy J, Croce O, Gilson E, Shkreli M.

    NPJ Regen Med. 2022 Feb 11;7(1):15. doi: 10.1038/s41536-022-00212-z.

    PMID: 35149726

  • COVID-19 vaccination and cancer immunotherapy: should they stick together?

    Brest P, Mograbi B, Hofman P, Milano G.

    Br J Cancer. 2022 Jan;126(1):1-3.

    doi: 10.1038/s41416-021-01618-0.

    PMID: 34799696; PMCID: PMC8603902.

  • Locus-specific chromatin profiling of evolutionarily young transposable elements

    Taylor D, Lowe R, Philippe C, Cheng KCL, Grant OA, Zabet NR, Cristofari G, Branco MR.

    Nucleic Acids Res. 2022 Apr 8;50(6):e33. doi: 10.1093/nar/gkab1232

    PMID: 34908129

  • Intrinsically high capacity of animal cells from a symbiotic cnidarian to deal with pro-oxidative conditions

    Cotinat P, Fricano C, Toullec G, Röttinger E, Barnay-Verdier S, Furla P

    Frontiers in Physiology, 2022.819111

    PMID: 35222085

  • Cancer induces a stress ileopathy depending on B-adrenergic receptors and promoting dysbiosis that contribute to carcinogenesis.

    Yonekura S, Terrisse S, Alves Costa Silva C, Lafarge A, Iebba V, Ferrere G, Goubet AG, Fahrner JE, Lahmar I, Ueda K, Mansouri G, Pizzato E, Ly P, Mazzenga M, Thelemaque C, Fidelle M, Jaulin F, Cartry J, Deloger M, Aglave M, Droin N, Opolon P, Puget A, Mann F, Neunlist M, Bessard A, Aymeric L, Matysiak-Budnik T, Bosq J, Hofman P, Duong CPM, Ugolini S, Quiniou V, Berrard S, Ryffel B, Kepp O, Kroemer G, Routy B, Lordello L, Bani MA, Segata N, Yousef Yengej F, Clevers H, Scoazec JY, Pasolli E, Derosa L, Zitvogel L.

    Cancer Discov. 2021 Dec 20:candisc.0999.2021.

    doi: 10.1158/2159-8290.CD-21-0999. Epub ahead of print.

    PMID: 34930787.

  • The LEGO® brick road to open science and biotechnology

    Boulter E, Colombelli J, Henriques R, Féral CC.

    Trends Biotechnol. 2022 Sep;40(9):1073-1087.

    PMID 35314074

  • Flip-flop genomics: Charting inversions in the human population.

    Lanciano S, Cristofari G.

    Cell. 2022 May 26;185(11):1811-1813. doi: 10.1016/j.cell.2022.05.002

    PMID: 35623326

  • CHCHD10 and SLP2 control the stability of the PHB complex: a key factor for motor neuron viability.

    Genin EC, Bannwarth S, Ropert B, Lespinasse F, Mauri-Crouzet A, Augé G, Fragaki K, Cochaud C, Donnarumma E, Lacas-Gervais S, Wai T, Paquis-Flucklinger V.

    Brain. 2022 Jun 3:awac197. doi: 10.1093/brain/awac197. 

    PMID: 35656794

  • Lung Adenocarcinoma Tumor Origin: A Guide for Personalized Medicine.

    Seguin L, Durandy M, Feral CC.

    Cancers (Basel). 2022 Mar 30;14(7):1759.

    PMID 35406531 

  •   The non-telomeric evolutionary trajectory of TRF2 in zebrafish reveals its specific roles in neurodevelopment and aging.
  • Selective pericentromeric heterochromatin dismantling caused by TP53 activation during senescence.

    Mendez-Bermudez A, Lototska L, Pousse M, Tessier F, Croce O, Latrick CM, Cherdyntseva V, Nassour J, Xiaohua J, Lu Y, Abbadie C, Gagos S, Ye J, Gilson

    Nucleic Acids Res. 2022 Jul 22;50(13):7493-7510. doi: 10.1093/nar/gkac603. PMID: 35819196

  • Loss of atm in Zebrafish as a Model of Ataxia-Telangiectasia Syndrome.
    Chen K, Wang P, Chen J, Ying Y, Chen Y, Gilson E, Lu Y, Ye J.
    Biomedicines. 2022 Feb 7;10(2):392. doi: 10.3390/biomedicines10020392. PMID: 35203601
  •   Telomeres as a sentinel of population decline in the context of global warming.


    Lemaître JF, Gaillard JM, Gilson E. Proc Natl Acad Sci U S A.
    2022 Aug 30;119(35):e2211349119. doi: 10.1073/pnas.2211349119. Epub 2022 Aug 10. PMID: 35947638
  • KRAS Addiction Promotes Cancer Cell Adaptation in Harsh Microenvironment Through Macropinocytosis

    Seguin L

    Subcell Biochem. 2022;98:189-204.

    PMID 35378709

  • Evolutionary conserved Mechano-Biochemical Marine Stimulation of Inversion, Gastrulation and Endomesoderm formation in multicellular Eukariota

    Nguyen NM, Merle T, Broders F, Brunet A-C, Battistella A, Linnea Land E-B, Sarron F, Jha A, Gennisson J-L, Röttinger E, Fernandez-Sanchez ME & Farge E. 

    Frontiers in Cell and Developmental Biology, 10: 992371

    PMID: 9754125

  • Automated Analysis of Proliferating Cells Spatial Organisation Predicts Prognosis in Lung Neuroendocrine Neoplasms.

    Bulloni M, Sandrini G, Stacchiotti I, Barberis M, Calabrese F, Carvalho L, Fontanini G, Alì G, Fortarezza F, Hofman P, Hofman V, Kern I, Maiorano E, Maragliano R, Marchiori D, Metovic J, Papotti M, Pezzuto F, Pisa E, Remmelink M, Serio G, Marzullo A, Trabucco SMR, Pennella A, De Palma A, Marulli G, Fassina A, Maffeis V, Nesi G, Naheed S, Rea F, Ottensmeier CH, Sessa F, Uccella S, Pelosi G, Pattini L.

    Cancers (Basel). 2021 Sep 29;13(19):4875.

    doi: 10.3390/cancers13194875.

    PMID: 34638359; PMCID: PMC8508355.

  • The Carcinogen Cadmium Activates Lysine 63 (K63)-Linked Ubiquitin-Dependent Signaling and Inhibits Selective Autophagy.

    Chargui A, Belaid A, Ndiaye PD, Imbert V, Samson M, Guigonis JM, Tauc M, Peyron JF, Poujeol P, Brest P, Hofman P, Mograbi B.

    Cancers (Basel). 2021 May 20;13(10):2490.

    doi: 10.3390/cancers13102490.

    PMID: 34065348; PMCID: PMC8161291.

  • Next-Generation Sequencing with Liquid Biopsies from Treatment-Naïve Non-Small Cell Lung Carcinoma Patients.

    Hofman P.

    Cancers (Basel). 2021 Apr 23;13(9):2049.

    doi: 10.3390/cancers13092049.

    PMID: 33922637; PMCID: PMC8122958.

  • Un trio de mécanismes au cœur de l’initiation de la régénération chez les animaux

    Vullien A, Röttinger E, Vervoort M et Gazave E

    Médecine / Sciences, 37:349 - 358

    PMID: 33908852

  • Small but Challenging Conjunctival Melanoma: New Insights, Paradigms and Future Perspectives.

    Nahon-Estève S, Bertolotto C, Picard-Gauci A, Gastaud L, Baillif S, Hofman P, Groulier A, Maschi C, Caujolle JP, Lassalle S, Martel A.

    Cancers (Basel). 2021 Nov 14;13(22):5691.

    doi: 10.3390/cancers13225691.

    PMID: 34830847; PMCID: PMC8616295.

  • Detecting Resistance to Therapeutic ALK Inhibitors in Tumor Tissue and Liquid Biopsy Markers: An Update to a Clinical Routine Practice.

    Hofman P.

    Cells. 2021 Jan 15;10(1):168.

    doi: 10.3390/cells10010168.

    PMID: 33467720; PMCID: PMC7830674.

  • Perspectives and Issues in the Assessment of SMARCA4 Deficiency in the Management of Lung Cancer Patients.

    Armon S, Hofman P, Ilié M.

    Cells. 2021 Jul 29;10(8):1920.

    doi: 10.3390/cells10081920.

    PMID: 34440689; PMCID: PMC8394288.

  • EGFR Status Assessment for Better Care of Early Stage Non-Small Cell Lung Carcinoma: What Is Changing in the Daily Practice of Pathologists?

    Hofman P. 

    Cells. 2021 Aug 21;10(8):2157.

    doi: 10.3390/cells10082157.

    PMID: 34440926; PMCID: PMC8392580.

  • More light on cancer and COVID-19 reciprocal interaction.

    Brest P, Mograbi B, Hofman P, Milano G.

    Br J Cancer. 2021 Apr;124(8):1344-1345.

    doi: 10.1038/s41416-020-01246-0. Epub 2021 Feb 3.

    PMID: 33531686; PMCID: PMC8039039.

  • Safety and cross-variant immunogenicity of a three-dose COVID-19 mRNA vaccine regimen in kidney transplant recipients.

    Massa F, Cremoni M, Gérard A, Grabsi H, Rogier L, Blois M, Couzin C, Hassen NB, Rouleau M, Barbosa S, Martinuzzi E, Fayada J, Bernard G, Favre G, Hofman P, Esnault VLM, Czerkinsky C, Seitz-Polski B, Glaichenhaus N, Sicard A. 

    EBioMedicine. 2021 Nov;73:103679.

    doi: 10.1016/j.ebiom.2021.103679. Epub 2021 Nov 8.

    PMID: 34763205; PMCID: PMC8573385.

  • Discovery of a new molecule inducing melanoma cell death: dual AMPK/MELK targeting for novel melanoma therapies.

    Jaune E, Cavazza E, Ronco C, Grytsai O, Abbe P, Tekaya N, Zerhouni M, Beranger G, Kaminski L, Bost F, Gesson M, Tulic M, Hofman P, Ballotti R, Passeron T, Botton T, Benhida R, Rocchi S.

    Cell Death Dis. 2021 Jan 11;12(1):64.

    doi: 10.1038/s41419-020-03344-6.

    PMID: 33431809; PMCID: PMC7801734.

  • New Targeted Therapies and Immunotherapies for Locally Advanced Periocular Malignant Tumours: Towards a New 'Eye-Sparing' Paradigm?

    Martel A, Lassalle S, Picard-Gauci A, Gastaud L, Montaudie H, Bertolotto C, Nahon-Esteve S, Poissonnet G, Hofman P, Baillif S.

    Cancers (Basel). 2021 Jun 5;13(11):2822.

    doi: 10.3390/cancers13112822.

    PMID: 34198863; PMCID: PMC8201354.

  • Expert consensus on perioperative immunotherapy for local advanced non-small cell lung cancer.

    Qiu B, Cai K, Chen C, Chen J, Chen KN, Chen QX, Cheng C, Dai TY, Fan J, Fan Z, Hu J, Hu WD, Huang YC, Jiang GN, Jiang J, Jiang T, Jiao WJ, Li HC, Li Q, Liao YD, Liu HX, Liu JF, Liu L, Liu Y, Long H, Luo QQ, Ma HT, Mao NQ, Pan XJ, Tan F, Tan LJ, Tian H, Wang D, Wang WX, Wei L, Wu N, Wu QC, Xiang J, Xu SD, Yang L, Zhang H, Zhang L, Zhang P, Zhang Y, Zhang Z, Zhu K, Zhu Y, Um SW, Oh IJ, Tomita Y, Watanabe S, Nakada T, Seki N, Hida T, Sasada S, Uchino J, Sugimura H, Dermime S, Cappuzzo F, Rizzo S, Cho WC, Crucitti P, Longo F, Lee KY, De Ruysscher D, Vanneste BGL, Furqan M, Sieren JC, Yendamuri S, Merrell KW, Molina JR, Metro G, Califano R, Bongiolatti S, Provencio M, Hofman P, Gao S, He J.

    Transl Lung Cancer Res. 2021 Sep;10(9):3713-3736.

    doi: 10.21037/tlcr-21-634.

    PMID: 34733623; PMCID: PMC8512472.

  • Targeting histone deacetylase enhances the therapeutic effect of Erastin-induced ferroptosis in EGFR-activating mutant lung adenocarcinoma.

    Zhang T, Sun B, Zhong C, Xu K, Wang Z, Hofman P, Nagano T, Legras A, Breadner D, Ricciuti B, Divisi D, Schmid RA, Peng RW, Yang H, Yao F.

    Transl Lung Cancer Res. 2021 Apr;10(4):1857-1872.

    doi: 10.21037/tlcr-21-303.

    PMID: 34012798; PMCID: PMC8107764.

  • Improved detection of mitochondrial DNA instability in mitochondrial genome maintenance disorders

    Bris C, Goudenège D, Desquiret-Dumas V, Gueguen N, Bannwarth S, Gaignard P, Rucheton B, Trimouille A, Allouche S, Rouzier C, Saadi S, Jardel C, Slama A, Barth M, Verny C, Spinazzi M, Cassereau J, Colin E, Armelle M, Pereon Y, Martin-Negrier ML, Paquis-Flucklinger V, Letournel F, Lenaers G, Bonneau D, Reynier P, Amati-Bonneau P, Procaccio V.

    Genet Med. 2021 May 26. doi: 10.1038/s41436-021-01206-w. Online ahead of print.

    PMID: 34040194

  • Targeting netrin-3 in small cell lung cancer and neuroblastoma.

    Jiang S, Richaud M, Vieugué P, Rama N, Delcros JG, Siouda M, Sanada M, Redavid AR, Ducarouge B, Hervieu M, Breusa S, Manceau A, Gattolliat CH, Gadot N, Combaret V, Neves D, Ortiz-Cuaran S, Saintigny P, Meurette O, Walter T, Janoueix-Lerosey I, Hofman P, Mulligan P, Goldshneider D, Mehlen P, Gibert B.

    EMBO Mol Med. 2021 Apr 9;13(4):e12878.

    doi: 10.15252/emmm.202012878. Epub 2021 Mar 15.

    PMID: 33719214; PMCID: PMC8033513.

  • [Usefulness of combined sequencing of the mitochondrial genome and a targeted panel of nuclear genes involved in mitochondrial diseases]

    Rucheton B, Ader F, Goudenege D, Filaut S, Legrand L, Bloch A, MitoDiag R, Fressart V, Bonnefont-Rousselot D, Mochel F, Lamari F, Richard P, Procaccio V, Bannwarth S.

    Ann Biol Clin (Paris). 2021 Feb 1;79(1):28-40. doi: 10.1684/abc.2021.1621.

    PMID: 33586649

  • Nematostella vectensis, an emerging model for deciphering the molecular and cellular mechanisms underlying whole-body regeneration

    Röttinger E

    Cells, Oct 8;10(10):2692

    PMID: 34685672

  • TDP-43 and PINK1 mediate CHCHD10 S59L mutation-induced defects in Drosophila and in vitro

    Baek M, Choe YJ, Bannwarth S, Kim J, Maitra S, Dorn GW 2nd, Taylor JP, Paquis-Flucklinger V, Kim NC.

    Nat Commun. 2021 Mar 26;12(1):1924. doi: 10.1038/s41467-021-22145-9.

    PMID: 33772006

  • Aborting meiosis allows recombination in sterile diploid yeast hybrids

    Mozzachiodi S, Tattini L, Llored A, Irizar A, Škofljanc N, D'Angiolo M, De Chiara M, Barré BP, Yue JX, Lutazi A, Loeillet S, Laureau R, Marsit S, Stenberg S, Albaud B, Persson K, Legras JL, Dequin S, Warringer J, Nicolas A, Liti G.
    Nature Communications. 2021 Nov 12;12(1):6564. doi: 10.1038/s41467-021-26883-8.
    PMID: 34772931

  • Cyclic uniaxial cell stretching in tissue culture using a LEGO®-based mechanical stretcher and a polydimethylsiloxane stretchable vessel.

    Boulter E*, Féral CC* (*co-corresponding).

    STAR Protoc. 2021 Apr 8;2(2):100437. eCollection 2021 Jun 18.

    PMID 33899018


  • The essentials of marine biotechnology

    Rotter A & COST Ocean4Biotech Consortium.

    Frontiers in Marine Science, March 16;8:629629

    Link to publication

  • Plk1, upregulated by HIF-2, mediates metastasis and drug resistance of clear cell renal cell carcinoma.

    Dufies M, Verbiest A, Cooley LS, Ndiaye PD, He X, Nottet N, Souleyreau W, Hagege A, Torrino S, Parola J, Giuliano S, Borchiellini D, Schiappa R, Mograbi B, Zucman-Rossi J, Bensalah K, Ravaud A, Auberger P, Bikfalvi A, Chamorey E, Rioux-Leclercq N, Mazure NM, Beuselinck B, Cao Y, Bernhard JC, Ambrosetti D, Pagès G.

    Commun Biol. 2021 Feb 5;4(1):166.

    doi: 10.1038/s42003-021-01653-w.

    PMID: 33547392; PMCID: PMC7865059.

  • Stem cells of aquatic invertebrates as an advanced tool for assessing ecotoxicological impacts

    Rosnera A, Armengaudb J, Ballarin L, Barnay-Verdier S, Cima F, Varela-Coelhoe A, Domart-Coulonf I, Drobneg D, Genevière AM, Kokalj AJ, Kotlarska E, Lyons DM, Mass T, Paza G, Pazdro K, Perić L, Ramšak A, Rakers S, Rinkevich B, Spagnuolo A, MichelaSugni M, Cambier S

    Sci Total Environ. 2021 Jun 1;771:144565

    PMID: 33736145

  • Horizontal acquisition of Symbiodiniaceae in the Anemonia viridis (Cnidaria, Anthozoa) species complex

    Porro B, Zamoum T, Mallien C, Hume BCC, Voolstra CR, Röttinger E, Furla P & Forcioli D.

    Molecular Ecology, 2021;30:391-405

    PMID: 33249664

  • L’anémone de mer Nematostella vectensis, un modèle émergent pour la recherche biomédicale : mécano-sensibilité, régénération et longévité

    Amiel RA, Michel V, Carvalho EJ, Shkreli M, Petit C & Röttinger E. 

    Médecine / Sciences, 37:167–177

    PMID: 33591260

  • Liquid biopsy for lung cancer screening: Usefulness of circulating tumor cells and other circulating blood biomarkers.

    Hofman P.

    Cancer Cytopathol. 2021 May;129(5):341-346.

    doi: 10.1002/cncy.22367. Epub 2020 Oct 2.

    PMID: 33007153.

  • Detection of EGFR Mutations From Plasma of NSCLC Patients Using an Automatic Cartridge-Based PCR System.

    Heeke S, Hofman V, Benzaquen J, Otto J, Tanga V, Zahaf K, Allegra M, Long-Mira E, Lassalle S, Marquette CH, Ilie M, Hofman P.

    Front Pharmacol. 2021 Apr 14;12:657743.

    doi: 10.3389/fphar.2021.657743.

    PMID: 33935776; PMCID: PMC8079969.

  • A small-molecule P2RX7 activator promotes anti-tumor immune responses and sensitizes lung tumor to immunotherapy

    Douguet L, Janho Dit Hreich S, Benzaquen J, Seguin L, Juhel T, Dezitter X, Duranton C, Ryffel B, Kanellopoulos J, Delarasse C, Renault N, Furman C, Homerin G, Féral C, Cherfils-Vicini J, Millet R, Adriouch S, Ghinet A, Hofman P, Vouret-Craviari V.

    Nat Commun. 2021 Jan 28;12(1):653

    PMID 33510147

  • Impact of expert pathologic review of thymic epithelial tumours on diagnosis and management in a real-life setting: A RYTHMIC study.

    Molina TJ, Bluthgen MV, Chalabreysse L, de Montpréville VT, de Muret A, Dubois R, Hofman V, Lantuejoul S, le Naoures C, Mansuet-Lupo A, Parrens M, Piton N, Rouquette I, Secq V, Girard N, Marx A, Besse B.

    Eur J Cancer. 2021 Jan;143:158-167.

    doi: 10.1016/j.ejca.2020.11.011. Epub 2020 Dec 11.

    PMID: 33316754.

  • TRAIL receptor-induced features of epithelial-to-mesenchymal transition increase tumour phenotypic heterogeneity: potential cell survival mechanisms.

    Peyre L, Meyer M, Hofman P, Roux J. 

    Br J Cancer. 2021 Jan;124(1):91-101.

    doi: 10.1038/s41416-020-01177-w. Epub 2020 Dec 1.

    PMID: 33257838; PMCID: PMC7782794.

  • Mutational Profile Evaluates Response and Survival to First-Line Chemotherapy in Lung Cancer.

    He Y, Song L, Wang H, Chen P, Liu Y, Sun H, Li X, Dang S, Liu G, Liu X, Chen S, Zhang X, Hofman P, Uchino J, Park HS, Pacheco JM, Tabbò F, Xu M, Dai J, He K, Yang Y, Zhou C; written on behalf of the AME Lung Cancer Collaborative Group.

    Adv Sci (Weinh). 2020 Dec 30;8(4):2003263.

    doi: 10.1002/advs.202003263.

    PMID: 33643802; PMCID: PMC7887584.

  • Inhibition of eIF5A hypusination reprogrammes metabolism and glucose handling in mouse kidney

    Cougnon M, Carcy R, Melis N, Rubera I, Duranton C, Dumas K, Tanti JF, Pons C, Soubeiran N, Shkreli M, Hauet T, Pellerin L, Giraud S, Blondeau N, Tauc M, Pisani DF.

    Cell Death Dis. 2021 Mar 17;12(4):283. doi: 10.1038/s41419-021-03577-z.

    PMID: 33731685

  • Multifunctionality of the Telomere-Capping Shelterin Complex Explained by Variations in Its Protein Composition.

     Ghilain C, Gilson E, Giraud-Panis MJ.

    Cells. 2021 Jul 11;10(7):1753. doi: 10.3390/cells10071753. PMID: 34359923

  • Neutrophils: mediating TelOxidation and senescence.

    Jacome Burbano MS, Cherfils-Vicini J, Gilson E.

    EMBO J. 2021 May 3;40(9):e108164. doi: 10.15252/embj.2021108164. Epub 2021 Apr 20. PMID: 33880795

  • The Power of Stress: The Telo-Hormesis Hypothesis.

    Jacome Burbano MS, Gilson E.

    Cells. 2021 May 11;10(5):1156. doi: 10.3390/cells10051156.

  • Macropinocytosis requires Gal-3 in a subset of patient-derived glioblastoma stem cells.

    Seguin L, Odouard S, Corlazzoli F, Haddad SA, Moindrot L, Calvo Tardón M, Yebra M, Koval A, Marinari E, Bes V, Guérin A, Allard M, Ilmjärv S, Katanaev VL, Walker PR, Krause KH, Dutoit V, Sarkaria JN, Dietrich PY, Cosset É.

    Commun Biol. 2021 Jun 10;4(1):718.

    PMID 34112916

  • Chemotherapy-induced transposable elements activate MDA5 to enhance haematopoietic regeneration

    PMID: 34611323

  • Sensing Stemness
  • New tools for 'ZEBRA-FISHING'
  • Mixing "good and bad" annoys neutrophils
  • Inflammation, Aging and Hematopoiesis: A Complex Relationship
  • ZFP451-mediated SUMOylation of SATB2 drives embryonic stem cell differentiation
  • Single-cell RNA sequencing reveals intratumoral heterogeneity in primary uveal melanomas and identifies HES6 as a driver of the metastatic disease.

    Pandiani C, Strub T, Nottet N, Cheli Y, Gambi G, Bille K, Husser C, Dalmasso M, Béranger G, Lassalle S, Magnone V, Pédeutour F, Irondelle M, Maschi C, Nahon-Estève S, Martel A, Caujolle JP, Hofman P, LeBrigand K, Davidson I, Baillif S, Barbry P, Ballotti R, Bertolotto C.

    Cell Death Differ. 2021 Jun;28(6):1990-2000.

    doi: 10.1038/s41418-020-00730-7. Epub 2021 Jan 18.

    PMID: 33462406; PMCID: PMC8185008.

  • The sea anemone Nematostella vectensis, an emerging model for biomedical research: Mechano-sensitivity, extreme regeneration and longevity

    Amiel AR, Michel V, Carvalho JE, Shkreli M, Petit C, Röttinger E.

    Med Sci (Paris). 2021 Feb;37(2):167-177. doi: 10.1051/medsci/2020282. Epub 2021 Feb 16.

    PMID: 33591260

  • Nascent RNA m6A modification at the heart of the gene-retrotransposon conflict

    Billon V, Cristofari G.

    Cell Res. 2021 Aug;31(8):829-831. doi: 10.1038/s41422-021-00518-5

    PMID: 34108664

  • To inhibit or to boost the ATP/P2RX7 pathway to fight cancer-that is the question.

    Janho Dit Hreich S, Benzaquen J, Hofman P, Vouret-Craviari V.

    Purinergic Signal. 2021 Dec;17(4):619-631.

    doi: 10.1007/s11302-021-09811-9. Epub 2021 Aug 4.

    PMID: 34347213; PMCID: PMC8677881.

  • Prospective Multicenter Validation of the Detection of ALK Rearrangements of Circulating Tumor Cells for Noninvasive Longitudinal Management of Patients With Advanced NSCLC.

    Ilié M, Mazières J, Chamorey E, Heeke S, Benzaquen J, Thamphya B, Boutros J, Tiotiu A, Fayada J, Cadranel J, Poudenx M, Moro-Sibilot D, Barlesi F, Thariat J, Clément-Duchêne C, Tomasini P, Hofman V, Marquette CH, Hofman P; STALKLUNG01 Study Consortium Investigators.

    J Thorac Oncol. 2021 May;16(5):807-816.

    doi: 10.1016/j.jtho.2021.01.1617. Epub 2021 Feb 3.

    PMID: 33545389.

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Klionsky DJ, ..., Brest P, ..., Hofman P, ..., Mograbi B, et al .

    Autophagy. 2021 Jan;17(1):1-382.

    doi: 10.1080/15548627.2020.1797280. Epub 2021 Feb 8.

    PMID: 33634751; PMCID: PMC7996087.

  • Genomic and evolutionary classification of lung cancer in never smokers.

    Zhang T, Joubert P, Ansari-Pour N, Zhao W, Hoang PH, Lokanga R, Moye AL, Rosenbaum J, Gonzalez-Perez A, Martínez-Jiménez F, Castro A, Muscarella LA, Hofman P, Consonni D, Pesatori AC, Kebede M, Li M, Gould Rothberg BE, Peneva I, Schabath MB, Poeta ML, Costantini M, Hirsch D, Heselmeyer-Haddad K, Hutchinson A, Olanich M, Lawrence SM, Lenz P, Duggan M, Bhawsar PMS, Sang J, Kim J, Mendoza L, Saini N, Klimczak LJ, Islam SMA, Otlu B, Khandekar A, Cole N, Stewart DR, Choi J, Brown KM, Caporaso NE, Wilson SH, Pommier Y, Lan Q, Rothman N, Almeida JS, Carter H, Ried T, Kim CF, Lopez-Bigas N, Garcia-Closas M, Shi J, Bossé Y, Zhu B, Gordenin DA, Alexandrov LB, Chanock SJ, Wedge DC, Landi MT.

    Nat Genet. 2021 Sep;53(9):1348-1359.

    doi: 10.1038/s41588-021-00920-0. Epub 2021 Sep 6.

    PMID: 34493867; PMCID: PMC8432745.

  • A small-molecule P2RX7 activator promotes anti-tumor immune responses and sensitizes lung tumor to immunotherapy.

    Douguet L, Janho Dit Hreich S, Benzaquen J, Seguin L, Juhel T, Dezitter X, Duranton C, Ryffel B, Kanellopoulos J, Delarasse C, Renault N, Furman C, Homerin G, Féral C, Cherfils-Vicini J, Millet R, Adriouch S, Ghinet A, Hofman P, Vouret-Craviari V.

    Nat Commun. 2021 Jan 28;12(1):653.

    doi: 10.1038/s41467-021-20912-2.

    PMID: 33510147; PMCID: PMC7843983.

  • The Unforeseen Path to the Superior Vena Cava.

    Boutros J, Benzaquen J, Marquette CH, Leroy S.

    Am J Respir Crit Care Med. 2021 Aug 1;204(3):e51-e53.

    doi: 10.1164/rccm.202011-4106IM.

    PMID: 34166167.


  • A pan-metazoan concept for adult stem cells: The wobbling Penrose landscape

    Rinkevich B, Ballarin L, Martinez P, Somorjai I, Ben-Hamo O, Borisenko I, Berezikov E, Ereskovsky A, Gazave E, Khnykin D, Manni L, Petukhova O, Rosner A, Röttinger E, Spagnuolo A, Sugni M, Tiozzo, S, Hobmayer, B

    Biological reviews, 2021 Oct 6.  doi: 10.1111/brv.12801

    PMID: 34617397

  • Association of TRF2 expression and myeloid-derived suppressor cells infiltration with clinical outcome of patients with cutaneous melanoma.

    Ilié M, Lantéri E, Chamorey E, Thamphya B, Hamila M, Montaudié H, Picard-Gauci A, Gardrat S, Passeron T, Lassalle S, Long-Mira E, Cherfils-Vicini J, Gilson E, Hofman V, Hofman P.

    Oncoimmunology. 2021 Mar 19;10(1):1901446.

    doi: 10.1080/2162402X.2021.1901446.

    PMID: 33796413; PMCID: PMC7993190.


  • From biomarkers to therapeutic targets: the promise of PD-L1 in thyroid autoimmunity and cancer.

    D'Andréa G, Lassalle S, Guevara N, Mograbi B, Hofman P.

    Theranostics. 2021 Jan 1;11(3):1310-1325.

    doi: 10.7150/thno.50333.

    PMID: 33391536; PMCID: PMC7738901.

  • PD-L1 regulation revisited: impact on immunotherapeutic strategies.

    Lucibello G, Mograbi B, Milano G, Hofman P, Brest P.

    Trends Mol Med. 2021 Sep;27(9):868-881.

    doi: 10.1016/j.molmed.2021.06.005. Epub 2021 Jun 26.

    PMID: 34187739.

  • New technologies for improved relevance in miRNA research.

    Jacquet K, Vidal-Cruchez O, Rezzonico R, Nicolini VJ, Mograbi B, Hofman P, Vassaux G, Mari B, Brest P.

    Trends Genet. 2021 Dec;37(12):1060-1063.

    doi: 10.1016/j.tig.2021.08.006. Epub 2021 Aug 30.

    PMID: 34474931.

  • Using Genetics To Dissect SARS-CoV-2 Infection.

    Brest P, Mograbi B, Hofman P, Milano G.

    Trends Genet. 2021 Mar;37(3):203-204.

    doi: 10.1016/j.tig.2020.11.007. Epub 2020 Nov 26.

    PMID: 33309104; PMCID: PMC7689311.

  • MDM2 amplification and fusion gene ss18-ssx in a poorly differentiated synovial sarcoma: A rare but puzzling conjunction

    Di Mauro I, Mescam-Mancini L, Chetaille B, Lae M, Pierron G, Dadone-Montaudie B, Bazin A, Bouvier C, Michiels JF, Pedeutour F.

    Neoplasia. 2020 Aug;22(8):311-321

    doi: 10.1016/j.neo.2020.05.003. Epub 2020 Jun 16

    PMID: 32559641

  • A Multicenter Phase II Study of Pazopanib in Patients with Unresectable Dermatofibrosarcoma Protuberans

    Delyon J, Porcher R, Battistella M, Meyer N, Adamski H, Bertucci F, Guillot B, Jouary T, Leccia MT, Dalac S, Mortier L, Ghrieb Z, Da Meda L, Vicaut E, Pedeutour F, Mourah S, Lebbe C.

    J Invest Dermatol. 2020 Sep 18:S0022-202X(20)32067-4

    doi: 10.1016/j.jid.2020.06.039

    PMID: 32956651

  • Superficial CD34-positive Fibroblastic Tumour: Unique Subungual Presentation with Confounding Clinical Findings Resembling Fibrokeratoma-like Bowen's Disease

    Perrin C, Pedeutour F, Dadone-Montaudié B, Ambrosetti D.

    Acta Derm Venereol. 2020 Dec 15

    doi: 10.2340/00015555-3727

    PMID: 33320273

  • The tumor suppressor microRNA let-7 inhibits human LINE-1 retrotransposition.

    Tristán-Ramos P, Rubio-Roldan A, Peris G, Sánchez L, Amador-Cubero S, Viollet S, Cristofari G, Heras SR.

    Nat Commun. 2020 Nov 11;11(1):5712. doi: 10.1038/s41467-020-19430-4

    PMID: 33177501

  • Hyperprogression under Immune Checkpoint Inhibitor: a potential role for germinal immunogenetics.

    Refae S, Gal J, Brest P, Giacchero D, Borchiellini D, Ebran N, Peyrade F, Guigay J, Milano G, Saada-Bouzid E.

    Sci Rep. 2020 Feb 27;10(1):3565. doi: 10.1038/s41598-020-60437-0.

    PMID: 32107407

  • Prospective evaluation of NGS-based liquid biopsy in untreated late stage non-squamous lung carcinoma in a single institution.

    Heeke S, Hofman V, Ilié M, Allegra M, Lespinet V, Bordone O, Benzaquen J, Boutros J, Poudenx M, Lalvée S, Tanga V, Salacroup C, Bonnetaud C, Marquette CH, Hofman P.

    J Transl Med. 2020 Feb 17;18(1):87. doi: 10.1186/s12967-020-02259-2.

    PMID: 32066459

  • A polyphenotypic malignant paediatric brain tumour presenting a MN1-PATZ1 fusion, no epigenetic similarities with CNS High-Grade Neuroepithelial Tumour with MN1 Alteration (CNS HGNET-MN1) and related to PATZ1-fused sarcomas

    Burel-Vandenbos F, Pierron G, Thomas C, Reynaud S, Gregoire V, Duhil de Benaze G, Croze S, Chivoret N, Honavar M, Figarella-Branger D, Maurage CA, Pedeutour F, Hasselblatt M, Godfraind C.

    Neuropathol Appl Neurobiol. 2020 Aug;46(5):506-509

    doi: 10.1111/nan.12626. Epub 2020 Jun 3

    PMID: 32397004

  • Independent prognostic value of ultra-sensitive quantification of tumor pre-treatment T790M subclones in EGFR mutated non-small cell lung cancer (NSCLC) treated by first/second generation TKI, depends on variant allele frequency (VAF): Results of the

    Beau-Faller M, Pencreach E, Leduc C, Blons H, Merlio JP, Bringuier PP, de Fraipont F, Escande F, Lemoine A, Ouafik L, Denis M, Hofman P, Lacave R, Melaabi S, Langlais A, Missy P, Morin F, Moro-Sibilot D, Barlesi F, Cadranel J; French Cooperative Thoracic Intergroup (IFCT).

    Lung Cancer. 2020 Feb;140:19-26. doi: 10.1016/j.lungcan.2019.10.013. Epub 2019 Nov 15.

    PMID: 31841714

  • Measuring and interpreting transposable element expression.

    Lanciano S, Cristofari G.

    Nat Rev Genet. 2020 Dec;21(12):721-736. doi: 10.1038/s41576-020-0251-y

    PMID: 32576954

  • Cyclic uniaxial mechanical stretching of cells using a LEGO ® parts-based mechanical stretcher system
    Boulter E, Tissot FS, Dilly J, Pisano S, Féral CC.
    J Cell Sci. 2020 Jan 6;133(1):jcs234666. doi: 10.1242/jcs.234666.
  • Role of cell-type specific nucleosome positioning in inducible activation of mammalian promoters

    Oruba A, Saccani S, van Essen D.

    Nat Commun. 2020 Feb 26;11(1):1075. doi: 10.1038/s41467-020-14950-5.

    PMID: 32103026

  • A yeast living ancestor reveals the origin of genomic introgressions

    D'Angiolo M, De Chiara M, Yue JX, Irizar A, Stenberg S, Persson K, Llored A, Barré B, Schacherer J, Marangoni R, Gilson E, Warringer J, Liti G@
    Nature. 2020 Nov;587(7834):420-425.
    PMID: 33177709

  • Enhancing Cooperation Between Academic Biobanks and Biomedical Industry: Better Mutual Understanding and New Collaborative Models Are Needed.

    Simeon-Dubach D, Roehrl MH, Hofman P, Puchois P.

    Biopreserv Biobank. 2020 Feb 11. doi: 10.1089/bio.2019.0095. [Epub ahead of print] No abstract available.

    PMID: 32043910

  • Soft tissue angiomatosis: another PIK3CA-related disorder

    Boccara O, Galmiche-Rolland L, Dadone-Montaudié B, Ariche-Maman S, Coulet F, Eyries M, Pannier S, Soupre V, Molina T, Pedeutour F, Fraitag S.

    Histopathology. 2020 Mar;76(4):540-549

    doi: 10.1111/his.14021. Epub 2020 Jan 24

    PMID: 31630434

  • Detection of tetraploidization in chromophobe renal cell carcinoma: Insights and pitfalls

    Di Mauro I, Ambrosetti D, Vignot L, Roussel JF, Dadone-Montaudie B, Peyron AC, Quintens H, Durand M, Amiel J, Pedeutour F.

    Genes Chromosomes Cancer. 2020 Jul 13

    doi: 10.1002/gcc.22886

    PMID: 32658344

  • Comparison of three sequencing panels used for the assessment of tumor mutational burden in non-small cell lung cancer demonstrates low comparability

    Heeke S, Benzaquen J, Hofman V, Long-Mira E, Lespinet V, Bordone O, Marquette CH, Delingette H, Ilié M, Hofman P.
    J Thorac Oncol. 2020 May 22. pii: S1556-0864(20)30417-2. doi: 10.1016/j.jtho.2020.05.013.
    PMID: 32450274

  • Germinal Immunogenetics predict treatment outcome for PD-1/PD-L1 checkpoint inhibitors.

    Refae S, Gal J, Ebran N, Otto J, Borchiellini D, Peyrade F, Chamorey E, Brest P, Milano G, Saada-Bouzid E.

    Invest New Drugs. 2020 Feb;38(1):160-171. doi: 10.1007/s10637-019-00845-w. Epub 2019 Aug 11.

    PMID: 31402427

  • Genetic alterations of malignant pleural mesothelioma: association with tumor heterogeneity and overall survival.

    Quetel L, Meiller C, Assié JB, Blum Y, Imbeaud S, Montagne F, Tranchant R, de Wolf J, Caruso S, Copin MC, Hofman V, Gibault L, Badoual C, Pintilie E, Hofman P, Monnet I, Scherpereel A, Le Pimpec-Barthes F, Zucman-Rossi J, Jaurand MC, Jean D.

    Mol Oncol. 2020 Feb 21. doi: 10.1002/1878-0261.12651. 

    PMID: 32083805

  • Open Questions for Harnessing Autophagy-Modulating Drugs in the SARS-CoV-2 War. 


    Brest P, Benzaquen J, Klionsky DJ, Hofman P, Mograbi B.

    Autophagy. 2020 Dec;16(12):2267-2270.

    doi: 10.1080/15548627.2020.1779531.

    PMID: 32521191; PMCID: PMC7751564.

  • Pyroglutamide-Based P2X7 Receptor Antagonists Targeting Inflammatory Bowel Disease

    Homerin G, Jawhara S, Dezitter X, Baudelet D, Dufrénoy P, Rigo B, Millet R, Furman C, Ragé G, Lipka E, Farce A, Renault N, Sendid B, Charlet R, Leroy J, Phanithavong M, Richeval C, Wiart JF, Allorge D, Adriouch S, Vouret-Craviari V, Ghinet A.

    J Med Chem. 2020 Mar 12;63(5):2074-2094. doi: 10.1021/acs.jmedchem.9b00584. Epub 2019 Sep 27.

    PubMed PMID: 31525963

  • Targeted Assessment of the EGFR Status as Reflex Testing in Treatment-Naive Non-Squamous Cell Lung Carcinoma Patients: A Single Laboratory Experience (LPCE, Nice, France)

    Lassalle S, Hofman V, Heeke S, Benzaquen J, Long E, Poudenx M, Lantéri E, Boutros J, Tanga V, Zahaf K, Lalvée S, Lespinet V, Bordone O, Félix JM, Bonnetaud C, Marquette C, Ilie M, Hofman P.

    Cancers (Basel). 2020 Apr 13;12(4). pii: E955.

    doi: 10.3390/cancers12040955.

    PubMed PMID: 32294880.

  • The power of immunotherapy plus platinum-based chemotherapy for locally advanced or early stage non-small cell lung cancer.

    Hofman P.

    Ann Transl Med. 2020 Mar;8(5):151.

    doi: 10.21037/atm.2020.01.91.

    PubMed PMID: 32309300; PubMed Central PMCID: PMC7154477.

  • Possible consequences of the COVID-19 pandemic on the use of biospecimens from cancer biobanks for research in academia and bioindustry

     Paul Hofman, Pascal Puchois, Patrick Brest, Hicham Lahlou, Daniel Simeon-Dubach

    Nat Med. 2020 May 7.


    PMID: 32382152

  • Real-world assessment of the BRAF status in non-squamous cell lung carcinoma using VE1 immunohistochemistry: A single laboratory experience (LPCE, Nice, France)

    Hofman V, Benzaquen J, Heeke S, Lassalle S, Poudenx M, Long E, Lantéri E, Bordone O, Lespinet V, Tanga V, Bonnetaud C, Bille Y, Ilié M, Marquette C, Barlesi F, Boutros J, Hofman P.

    Lung Cancer. 2020 May 5;145:58-62.

    PubMed PMID: 32408133

  • Opposing p53 and mToR/AKT promote an in vivo switch from apotosis to senescence upon telomere shortening in zebrafish

    El Maï M, Marzullo M, de Castro IP, Ferreira MG.

    Elife. 2020 May 19;9. pii: e54935. doi: 10.7554/eLife.54935.

    PMID: 32427102
  • ERK mediated loss of miR-199a-3p and induction of EGR1 act as a “toggle switch” of GBM cell dedifferentiation into NANOG- and OCT4- positive cells

    Almairac F, Turchi L, Sakakini N, Debruyne DN, Elkeurti S, Gjernes E, Polo B, Bianchini L, Fontaine D, Paquis P, Chneiweiss H, Junier M-P, Verrando P, Burel-Vandenbos F and Virolle T.

    Cancer Res 2020, 80: 3236-3250.

    doi: 10.1158/0008-5472.CAN-19-0855

    PMID: 32366479

  • Telomere shortening produces an inflammatory environment that increases tumor incidence in zebrafish

    Lex K, Maia Gil M, Lopes-Bastos B, Figueira M, Marzullo M, Giannetti K, Carvalho T, Ferreira MG

    Proc Natl Acad Sci U S A. pii: 201920049. doi: 10.1073/pnas.1920049117.

    PMID: 32554492

  • For full publication list, please go to:
  • Intragenic Repeat Expansion in the Cell Wall Protein Gene HPF1 Controls Yeast Chronological Aging

    Barré BP@, Hallin J, Yue JX, Persson K, Mikhalev E, Irizar A, Thompson D, Molin M, Warringer J, Liti G@

    Genome Research. 2020; 30(5):697-710

    PMID: 32277013

  • Discordant Evolution of Mitochondrial and Nuclear Yeast Genomes at Population Level

    De Chiara M, Friedrich A, Barré B, Breitenbach M, Schacherer J@, Liti G@

    BMC Biology. 2020; 18(1):49

    PMID: 32393264

  • Experimental tools to study regeneration in the sea anemone Nematostella vectensis

    Amiel RA & Röttinger E

    Methods in Molecular Biology. Editor: David Carroll. 2021;2219:69-80

    PMID: 33074534

  • Transcriptomic Analysis in the Sea Anemone Nematostella vectensis

    Warner FJ & Röttinger E

    Methods in Molecular Biology. Editor: David Carroll. 2021;2219:231-240

    PMID: 33074544

  • Cryopreserved cnidarian cells: A powerful tool for cell-culture based functional assays

    Fricano C, Röttinger E, Furla P & Barnay-Verdier S.

    Cells, Nov 26;9(12):2541

    PMID: 33256018

  • High throughput profiling of undifferentiated pleomorphic sarcomas identifies two main subgroups with distinct immune profile, clinical outcome and sensitivity to targeted therapies

    Toulmonde M, Lucchesi C, Verbeke S, Crombe A, Adam J, Geneste D, Chaire V, Laroche-Clary A, , Perret R, Bertucci F,  Bertolo F, Bianchini L, Dadone-Montaudié B, Hembrough T, Sweet S, Kim YJ, Cecchi F, Le Loarer F, Italiano A.

    EBioMedicine 62, 2020.

    doi: 10.1016/j.ebiom.2020.103131

    PMID: 33254023

  • Novel therapeutic insights in dedifferentiated liposarcoma: a role for FGFR and MDM2 dual targeting

    Dadone-Montaudié B, Laroche-Clary A, Mongis A, Chamorey E, Di Mauro I, Chaire V, Finetti P, Schiappa R, Le Loarer F, Birtwisle-Peyrottes I, Michiels J-F, Bertucci F, Pedeutour F, Italiano A, Bianchini L.

    Cancers 2020, 12: 3058

    doi: 10.3390/cancers12103058

    PMID: 33092134

  • The diversity of metazoan muscles and their regenerative potential across animals

    Zullo L, Bozzo M, Di Clemente A, Mancini F, Megighian A, Nesher N, Röttinger E, Shomrat T, Tiozzo S, Zullo A, Candiani S. 

    Cells. 9, 2020 Aug 19;9(9):1925

    PMID: 32825163

  • Intracranial chondromas: A histopathologic and molecular study of three cases

    Tauziède-Espariat A, Burel-Vandenbos F, Pedeutour F, Gareton A, Saffroy R, Andreiuolo F, Blauwblomme T, Dangouloff-Ros V, Boddaert N, Lechapt E, Chrétien F, Varlet P.

    Clin Neuropathol. 2020 Jul/Aug;39(4):171-178

    doi: 10.5414/NP301238

    PMID: 31983386

  • Challenges and issues surrounding the use for translational research of human samples obtained during the COVID-19 pandemic from lung cancer patients.

    Hofman P.

    Transl Lung Cancer Res. 2020 Aug;9(4):1543-1553.

    doi: 10.21037/tlcr-20-594.

    PMID: 32953526; PMCID: PMC7481610.

  • A Single-Cell Atlas of the Human Healthy Airways.

    Deprez M, Zaragosi LE, Truchi M, Becavin C, Ruiz García S, Arguel MJ, Plaisant M, Magnone V, Lebrigand K, Abelanet S, Brau F, Paquet A, Pe'er D, Marquette CH, Leroy S, Barbry P.

    Am J Respir Crit Care Med. 2020 Dec 15;202(12):1636-1645.

    doi: 10.1164/rccm.201911-2199OC.

    PMID: 32726565.

  • Evidences of a Direct Relationship between Cellular Fuel Supply and Ciliogenesis Regulated by Hypoxic VDAC1-ΔC.

    Meyenberg Cunha-de Padua M, Fabbri L, Dufies M, Lacas-Gervais S, Contenti J, Voyton C, Fazio S, Irondelle M, Mograbi B, Rouleau M, Sadaghianloo N, Rovini A, Brenner C, Craigen WJ, Bourgeais J, Herault O, Bost F, Mazure NM.

    Cancers (Basel). 2020 Nov 23;12(11):3484.

    doi: 10.3390/cancers12113484.

    PMID: 33238609; PMCID: PMC7700438.

  • Circulating Tumour DNA Is an Independent Prognostic Biomarker for Survival in Metastatic BRAF or NRAS-Mutated Melanoma Patients.

    Herbreteau G, Vallée A, Knol AC, Théoleyre S, Quéreux G, Frénard C, Varey E, Hofman P, Khammari A, Dréno B, Denis MG.

    Cancers (Basel). 2020 Jul 11;12(7):1871.

    doi: 10.3390/cancers12071871.

    PMID: 32664549; PMCID: PMC7409003.

  • QT Interval Prolongation Under Hydroxychloroquine/Azithromycin Association for Inpatients With SARS-CoV-2 Lower Respiratory Tract Infection.

    Bun SS, Taghji P, Courjon J, Squara F, Scarlatti D, Theodore G, Baudouy D, Sartre B, Labbaoui M, Dellamonica J, Doyen D, Marquette CH, Levraut J, Esnault V, Bun SS, Ferrari E.

    Clin Pharmacol Ther. 2020 Nov;108(5):1090-1097.

    doi: 10.1002/cpt.1968. Epub 2020 Jul 20.

    PMID: 32588427; PMCID: PMC7361407.

  • Pyroglutamide-Based P2X7 Receptor Antagonists Targeting Inflammatory Bowel Disease.

    Homerin G, Jawhara S, Dezitter X, Baudelet D, Dufrénoy P, Rigo B, Millet R, Furman C, Ragé G, Lipka E, Farce A, Renault N, Sendid B, Charlet R, Leroy J, Phanithavong M, Richeval C, Wiart JF, Allorge D, Adriouch S, Vouret-Craviari V, Ghinet A.

    J Med Chem. 2020 Mar 12;63(5):2074-2094.

    doi: 10.1021/acs.jmedchem.9b00584. Epub 2019 Sep 27.

    PMID: 31525963.

  • "Interchangeability" of PD-L1 immunohistochemistry assays: a meta-analysis of diagnostic accuracy.

    Torlakovic E, Lim HJ, Adam J, Barnes P, Bigras G, Chan AWH, Cheung CC, Chung JH, Couture C, Fiset PO, Fujimoto D, Han G, Hirsch FR, Ilie M, Ionescu D, Li C, Munari E, Okuda K, Ratcliffe MJ, Rimm DL, Ross C, Røge R, Scheel AH, Soo RA, Swanson PE, Tretiakova M, To KF, Vainer GW, Wang H, Xu Z, Zielinski D, Tsao MS.

    Mod Pathol. 2020 Jan;33(1):4-17.

    doi: 10.1038/s41379-019-0327-4. Epub 2019 Aug 5.

    PMID: 31383961; PMCID: PMC6927905.

  • Allergy Evaluation of Hypersensitivity to Platinum Salts and Taxanes: A Six-Year Experience.

    Pradelli J, Verdoire P, Boutros J, Frin AC, Follana P, Duquesne J, Marquette CH, Benzaquen J, Ben Hayoun M, Leroy S.

    J Allergy Clin Immunol Pract. 2020 May;8(5):1658-1664.

    doi: 10.1016/j.jaip.2019.12.032. Epub 2020 Jan 7.

    PMID: 31918017.

  • Identification of a new aggressive axis driven by ciliogenesis and absence of VDAC1-ΔC in clear cell Renal Cell Carcinoma patients.

    Fabbri L, Dufies M, Lacas-Gervais S, Gardie B, Gad-Lapiteau S, Parola J, Nottet N, Meyenberg Cunha de Padua M, Contenti J, Borchiellini D, Ferrero JM, Leclercq NR, Ambrosetti D, Mograbi B, Richard S, Viotti J, Chamorey E, Sadaghianloo N, Rouleau M, Craigen WJ, Mari B, Clavel S, Pagès G, Pouysségur J, Bost F, Mazure NM.

    Theranostics. 2020 Feb 3;10(6):2696-2713.

    doi: 10.7150/thno.41001.

    PMID: 32194829; PMCID: PMC7052902.

  • Comprehensive Molecular and Pathologic Evaluation of Transitional Mesothelioma Assisted by Deep Learning Approach

    Galateau Salle F, Le Stang N, Tirode F, Courtiol P, Nicholson AG, Tsao MS, Tazelaar HD, Churg A, Dacic S, Roggli V, Pissaloux D, Maussion C, Moarii M, Beasley MB, Begueret H, Chapel DB, Copin MC, Gibbs AR, Klebe S, Lantuejoul S, Nabeshima K, Vignaud JM, Attanoos R, Brcic L, Capron F, Chirieac LR, Damiola F, Sequeiros R, Cazes A, Damotte D, Foulet A, Giusiano-Courcambeck S, Hiroshima K, Hofman V, Husain AN, Kerr K, Marchevsky A, Paindavoine S, Picquenot JM, Rouquette I, Sagan C, Sauter J, Thivolet F, Brevet M, Rouvier P, Travis WD, Planchard G, Weynand B, Clozel T, Wainrib G, Fernandez-Cuesta L, Pairon JC, Rusch V, Girard N.

    Comprehensive Molecular and Pathologic Evaluation of Transitional Mesothelioma Assisted by Deep Learning Approach: A Multi-Institutional Study of the International Mesothelioma Panel from the MESOPATH Reference Center.

    J Thorac Oncol. 2020 Jun;15(6):1037-1053.

    doi: 10.1016/j.jtho.2020.01.025. Epub 2020 Mar 9.

    PMID: 32165206.

  • New insights into the interaction of the immune system with non-small cell lung carcinomas.

    Hofman P.

    Transl Lung Cancer Res. 2020 Oct;9(5):2199-2213.

    doi: 10.21037/tlcr-20-178.

    PMID: 33209644; PMCID: PMC7653157.

  • Long-lived post-mitotic cell aging: is a telomere clock at play?

    Jacome Burbano MS, Gilson E.

    Mech Ageing Dev. 2020 Jul;189:111256. doi: 10.1016/j.mad.2020.111256. Epub 2020 May 4. PMID: 32380018 Review.

  • Liquid Biopsy for Solid Ophthalmic Malignancies: An Updated Review and Perspectives.

    Martel A, Baillif S, Nahon-Esteve S, Gastaud L, Bertolotto C, Roméo B, Mograbi B, Lassalle S, Hofman P.

    Cancers (Basel). 2020 Nov 6;12(11):3284. doi: 10.3390/cancers12113284.

    PMID: 33172021; PMCID: PMC7694640.

  • P2RX7B is a new theranostic marker for lung adenocarcinoma patients.

    Benzaquen J, Dit Hreich SJ, Heeke S, Juhel T, Lalvee S, Bauwens S, Saccani S, Lenormand P, Hofman V, Butori M, Leroy S, Berthet JP, Marquette CH, Hofman P, Vouret-Craviari V.

    Theranostics. 2020 Aug 29;10(24):10849-10860. doi: 10.7150/thno.48229.

    PMID: 33042257; PMCID: PMC7532666.

  • Host Polymorphisms May Impact SARS-CoV-2 Infectivity.

    Brest P, Refae S, Mograbi B, Hofman P, Milano G.

    Trends Genet. 2020 Nov;36(11):813-815.

    doi: 10.1016/j.tig.2020.08.003. Epub 2020 Aug 10.

    PMID: 32828550; PMCID: PMC7416730.

  • Inflammation-sepsis and catalytic antibodies

    Barnay-Verdier S, Maréchal V, Padmanabhan V, Kamalanathan A.S, Borde C

    Inflammation. Editor:Jyotirmay B and Chandrashekara S.

    Link to book

  • Emergence of antibodies endowed with proteolytic activity against High-mobility group box 1 protein (HMGB1) in patients surviving septic shock

    Barnay-Verdier S, Borde C, Fattoum L, Wootla B, Lacroix-Desmazes S, Kaveri S, Maréchal V

    Cellular Immunology, 347, 104020

    PMID: 31767118

  • Dynamic Cardiolipin Synthesis Is Required for CD8 + T Cell Immunity
  • Common variants in signaling transcription-factor-binding sites drive phenotypic variability in red blood cell traits
  • Heterochromatin replication goes hand in hand with telomere protection.

    Mendez-Bermudez A, Giraud-Panis MJ, Ye J, Gilson E.

    Nat Struct Mol Biol. 2020 Apr;27(4):313-318. doi: 10.1038/s41594-020-0400-1. Epub 2020 Mar 30. PMID: 32231287 Review.

  • DNA FISH Diagnostic Assay on Cytological Samples of Thyroid Follicular Neoplasms.

    Vielh P, Balogh Z, Suciu V, Richon C, Job B, Meurice G, Valent A, Lacroix L, Marty V, Motte N, Dessen P, Caillou B, Ghuzlan AA, Bidart JM, Lazar V, Hofman P, Scoazec JY, El-Naggar AK, Schlumberger M.

    Cancers (Basel). 2020 Sep 6;12(9):2529.

    doi: 10.3390/cancers12092529.

    PMID: 32899953; PMCID: PMC7564487.

  • Comparison of unsupervised machine-learning methods to identify metabolomic signatures in patients with localized breast cancer.

    Gal J, Bailleux C, Chardin D, Pourcher T, Gilhodes J, Jing L, Guigonis JM, Ferrero JM, Milano G, Mograbi B, Brest P, Chateau Y, Humbert O, Chamorey E.

    Comput Struct Biotechnol J. 2020 Jun 3;18:1509-1524.

    doi: 10.1016/j.csbj.2020.05.021.

    PMID: 32637048; PMCID: PMC7327012.

  • Lung cancer biomarker testing: perspective from Europe.

    Thunnissen E, Weynand B, Udovicic-Gagula D, Brcic L, Szolkowska M, Hofman P, Smojver-Ježek S, Anttila S, Calabrese F, Kern I, Skov B, Perner S, Dale VG, Eri Z, Haragan A, Leonte D, Carvallo L, Prince SS, Nicholson S, Sansano I, Ryska A.

    Transl Lung Cancer Res. 2020 Jun;9(3):887-897.

    doi: 10.21037/tlcr.2020.04.07.

    PMID: 32676354; PMCID: PMC7354119.

  • Global impact of the COVID-19 pandemic on cytopathology practice: Results from an international survey of laboratories in 23 countries.

    Vigliar E, Cepurnaite R, Alcaraz-Mateos E, Ali SZ, Baloch ZW, Bellevicine C, Bongiovanni M, Botsun P, Bruzzese D, Bubendorf L, Büttner R, Canberk S, Capitanio A, Casadio C, Cazacu E, Cochand-Priollet B, D'Amuri A, Eloy C, Engels M, Fadda G, Fontanini G, Fulciniti F, Hofman P, Iaccarino A, Ieni A, Jiang XS, Kakudo K, Kern I, Kholova I, Liu C, Lobo A, Lozano MD, Malapelle U, Maleki Z, Michelow P, Musayev J, Özgün G, Oznur M, Peiró Marqués FM, Pisapia P, Poller D, Pyzlak M, Robinson B, Rossi ED, Roy-Chowdhuri S, Saieg M, Savic Prince S, Schmitt FC, Javier Seguí Iváñez F, Štoos-Veić T, Sulaieva O, Sweeney BJ, Tuccari G, van Velthuysen ML, VanderLaan PA, Vielh P, Viola P, Voorham R, Weynand B, Zeppa P, Faquin WC, Pitman MB, Troncone G.

    Cancer Cytopathol. 2020 Dec;128(12):885-894.

    doi: 10.1002/cncy.22373. Epub 2020 Oct 27.

    PMID: 33108683.

  • Single-fiber studies for assigning pathogenicity of eight mitochondrial DNA variants associated with mitochondrial diseases

    Zereg E, Chaussenot A, Morel G, Bannwarth S, Sacconi S, Soriani MH, Attarian S, Cano A, Pouget J, Bellance R, Tranchant C, Lannes B, de Paula AM, Saadi Ait-El-Mkadem S, Chafino B, Berthet M, Fragaki K, Paquis-Flucklinger V, Rouzier C.

    Hum Mutat. 2020 Aug;41(8):1394-1406. doi: 10.1002/humu.24037. Epub 2020 Jun 12.

    PMID: 32419253

  • Clinical phenotype of mitochondrial diabetes due to rare mitochondrial DNA mutations

    Decoux-Poullot AG, Bannwarth S, Procaccio V, Lebre AS, Jardel C, Vialettes B, Paquis-Flucklinger V, Chevalier N.

    Ann Endocrinol (Paris). 2020 Jun;81(2-3):68-77. doi: 10.1016/j.ando.2020.04.007. Epub 2020 Apr 28.

    PMID: 32409007

  • Multi-Omics Approaches to Improve Mitochondrial Disease Diagnosis: Challenges, Advances, and Perspectives

    Labory J, Fierville M, Ait-El-Mkadem S, Bannwarth S, Paquis-Flucklinger V, Bottini S.

    Front Mol Biosci. 2020 Nov 2;7:590842. doi: 10.3389/fmolb.2020.590842. eCollection 2020.

    PMID: 33240932

  • Accumulation of amyloid precursor protein C-terminal fragments triggers mitochondrial structure, function, and mitophagy defects in Alzheimer's disease models and human brains

    Vaillant-Beuchot L, Mary A, Pardossi-Piquard R, Bourgeois A, Lauritzen I, Eysert F, Kinoshita PF, Cazareth J, Badot C, Fragaki K, Bussiere R, Martin C, Mary R, Bauer C, Pagnotta S, Paquis-Flucklinger V, Buée-Scherrer V, Buée L, Lacas-Gervais S, Checler F, Chami M.

    Acta Neuropathol. 2021 Jan;141(1):39-65. doi: 10.1007/s00401-020-02234-7. Epub 2020 Oct 20.

    PMID: 33079262 

  • Molecular diagnosis and genetic counseling for spinal muscular atrophy (SMA)

    Rouzier C, Chaussenot A, Paquis-Flucklinger V.

    Arch Pediatr. 2020 Dec;27(7S):7S9-7S14. doi: 10.1016/S0929-693X(20)30270-0.

    PMID: 33357600 

  • A multifactorial score including autophagy for prognosis and care of COVID-19 patients

    Domdom MA, Brest P, Grosjean I, Roméo B, Landi MT, Gal J, Klionsky DJ, Hofman P, Mograbi B.

    Autophagy. 2020 Dec;16(12):2276-2281.

    doi: 10.1080/15548627.2020.1844433.

    PMID: 33249989; PMCID: PMC7751655.

  • Immunotherapy beyond progression in patients with advanced non-small cell lung cancer.

    Ge X, Zhang Z, Zhang S, Yuan F, Zhang F, Yan X, Han X, Ma J, Wang L, Tao H, Li X, Zhi X, Huang Z, Hofman P, Prelaj A, Banna GL, Mutti L, Hu Y, Wang J.

    Transl Lung Cancer Res. 2020 Dec;9(6):2391-2400.

    doi: 10.21037/tlcr-20-1252.

    PMID: 33489801; PMCID: PMC7815351.

  • Circulating tumour cells as a potential biomarker for lung cancer screening: a prospective cohort study.

    Marquette CH, Boutros J, Benzaquen J, Ferreira M, Pastre J, Pison C, Padovani B, Bettayeb F, Fallet V, Guibert N, Basille D, Ilie M, Hofman V, Hofman P; AIR project Study Group.

    Lancet Respir Med. 2020 Jul;8(7):709-716.

    doi: 10.1016/S2213-2600(20)30081-3. Erratum in: Lancet Respir Med. 2020 Dec;8(12):e94.

    PMID: 32649919.

  • Profiling the Non-genetic Origins of Cancer Drug Resistance with a Single-Cell Functional Genomics Approach Using Predictive Cell Dynamics.

    Meyer M, Paquet A, Arguel MJ, Peyre L, Gomes-Pereira LC, Lebrigand K, Mograbi B, Brest P, Waldmann R, Barbry P, Hofman P, Roux J.

    Cell Syst. 2020 Oct 21;11(4):367-374.e5.

    doi: 10.1016/j.cels.2020.08.019. Epub 2020 Sep 23.

    PMID: 33099406.

  • Predictive molecular pathology in non-small cell lung cancer in France: The past, the present and the perspectives.

    Hofman P, Rouleau E, Sabourin JC, Denis M, Deleuze JF, Barlesi F, Laurent-Puig P.

    Cancer Cytopathol. 2020 Sep;128(9):601-610.

    doi: 10.1002/cncy.22318.

    PMID: 32885912.

  • PD-L1 Expression in 65 Conjunctival Melanomas and Its Association with Clinical Outcome.

    Lassalle S, Nahon-Esteve S, Frouin E, Boulagnon-Rombi C, Josselin N, Cassoux N, Barnhill R, Scheller B, Baillif S, Hofman P.

    Int J Mol Sci. 2020 Nov 30;21(23):9147.

    doi: 10.3390/ijms21239147.

    PMID: 33266349; PMCID: PMC7731195.

  • CT-guided percutaneous biopsies of mediastinal and paramediastinal masses in the lateral decubitus position.

    Padovani B, Boutros J, Marquette CH, Hofman V, Ducreux D, Mouroux J, Diascorn Y, Leroy S.

    Eur Radiol. 2020 Jun;30(6):3146-3151.

    doi: 10.1007/s00330-020-06659-2. Epub 2020 Feb 17.

    PMID: 32065281.

  • Long Term Pharmacological Perturbation of Autophagy in Mice: Are HCQ Injections a Relevant Choice?

    Masson JD, Blanchet B, Periou B, Authier FJ, Mograbi B, Gherardi RK, Crépeaux G.

    Biomedicines. 2020 Mar 1;8(3):47.

    doi: 10.3390/biomedicines8030047.

    PMID: 32121613; PMCID: PMC7148514.

  • Independent prognostic value of ultra-sensitive quantification of tumor pre-treatment T790M subclones in EGFR mutated non-small cell lung cancer (NSCLC) treated by first/second generation TKI, depends on variant allele frequency (VAF)

    Beau-Faller M, Pencreach E, Leduc C, Blons H, Merlio JP, Bringuier PP, de Fraipont F, Escande F, Lemoine A, Ouafik L, Denis M, Hofman P, Lacave R, Melaabi S, Langlais A, Missy P, Morin F, Moro-Sibilot D, Barlesi F, Cadranel J; French Cooperative Thoracic Intergroup (IFCT).

     Independent prognostic value of ultra-sensitive quantification of tumor pre-treatment T790M subclones in EGFR mutated non-small cell lung cancer (NSCLC) treated by first/second generation TKI, depends on variant allele frequency (VAF): Results of the French cooperative thoracic intergroup (IFCT) biomarkers France project.

    Lung Cancer. 2020 Feb;140:19-26.

    doi: 10.1016/j.lungcan.2019.10.013. Epub 2019 Nov 15.

    PMID: 31841714.

  • VEGF-Related Germinal Polymorphisms May Identify a Subgroup of Breast Cancer Patients with Favorable Outcome under Bevacizumab-Based Therapy

    Gal J, Milano G, Brest P, Ebran N, Gilhodes J, Llorca L, Dubot C, Romieu G, Desmoulins I, Brain E, Goncalves A, Ferrero JM, Cottu PH, Debled M, Tredan O, Chamorey E, Merlano MC, Lemonnier J, Etienne-Grimaldi MC, Pierga JY.

    VEGF-Related Germinal Polymorphisms May Identify a Subgroup of Breast Cancer Patients with Favorable Outcome under Bevacizumab-Based Therapy-A Message from COMET, a French Unicancer Multicentric Study.

    Pharmaceuticals (Basel). 2020 Nov 23;13(11):414.

    doi: 10.3390/ph13110414.

    PMID: 33238394; PMCID: PMC7700430.

  • Accuracy of prenatal screening for congenital heart disease in population: A retrospective study in Southern France

    Suard C, Flori A, Paoli F, Loundou A, Fouilloux V, Sigaudy S, Michel F, Antomarchi J, Moceri P, Paquis-Flucklinger V, D'Ercole C, Bretelle F.

    PLoS One. 2020 Oct 5;15(10):e0239476. doi: 10.1371/journal.pone.0239476. eCollection 2020.

    PMID: 33017437


  • 7th Euro Evo Devo meeting: Report on the "Evolution of regeneration in Metazoa" symposium

    Gazave E, Röttinger E

    J Exp Zool B Mol Dev Evol. 2019 Aug 28.

    PMID: 31461214

  • simuG: a general-purpose genome simulator

    Yue JX, Liti G.

    Bioinformatics. 2019. [Epub ahead of print]
    PMID: 31116378

  • Accurate tracking of the mutational landscape of diploid hybrid genomes

    Tattini L, Tellini N, Mozzachiodi S, D'Angiolo M, Loeillet S, Nicolas A, Liti G.

    Mol Biol Evol. 2019. [Epub ahead of print]

    PMID: 31397846
  • Next-generation phylogeography of the cockle Cerastoderma glaucum: Highly heterogeneous genetic differentiation in a lagoon species

    Sromek L, Forcioli D, Lasota R, Furla P, Wolowicz M

    Ecol Evol. 2019 Mar 27;9(8):4667-4682

    PMID: 31031934

  • Inhibiting TRF1 upstream signaling pathways to target telomeres in cancer cells

    Cherfils-Vicini J, Gilson E.

    EMBO Mol Med. 2019 Jul;11(7):e10845. doi: 10.15252/emmm.201910845. 

    PMID: 31273935

  • Cancer cells induce immune escape via glycocalyx changes controlled by the telomeric protein TRF2

    Cherfils-Vicini J, Iltis C, Cervera L, Pisano S, Croce O, Sadouni N, Győrffy B, Collet R, Renault VM, Rey-Millet M, Leonetti C, Zizza P, Allain F, Ghiringhelli F, Soubeiran N, Shkreli M, Vivier E, Biroccio A, Gilson E.

    EMBO J. 2019 Jun 3;38(11). pii: e100012. doi: 10.15252/embj.2018100012. Epub 2019 Apr 18.

    PMID: 31000523

  • Mitochondrial defect in muscle precedes neuromuscular junction degeneration and motor neuron death in CHCHD10S59L/+ mouse

    Genin EC, Madji Hounoum B, Bannwarth S, Fragaki K, Lacas-Gervais S, Mauri-Crouzet A, Lespinasse F, Neveu J, Ropert B, Augé G, Cochaud C, Lefebvre-Omar C, Bigou S, Chiot A, Mochel F, Boillée S, Lobsiger CS, Bohl D, Ricci JE, Paquis-Flucklinger V.

    Acta Neuropathol. 2019 Jul;138(1):123-145.

    PMID: 30874923
  • Tumor-Stroma Mechanics Coordinate Amino Acid Availability to Sustain Tumor Growth and Malignancy.

    Bertero T, Oldham WM, Grasset EM, Bourget I, Boulter E, Pisano S, Hofman P, Bellvert F, Meneguzzi G, Bulavin DV, Estrach S, Feral CC, Chan SY, Bozec A, Gaggioli C.

    Cell Metab. 2019 Jan 8;29(1):124-140.e10. doi: 10.1016/j.cmet.2018.09.012. Epub 2018 Oct 4.

    PMID 30293773

  • Expanding Tara Oceans Protocols for Underway, Ecosystemic Sampling of the Ocean-Atmosphere Interface During Tara Pacific Expedition (2016–2018)

    Gabriel Gorsky, Guillaume Bourdin, Fabien Lombard, Maria Luiza Pedrotti, Samuel Audrain, Nicolas Bin, Emmanuel Boss, Chris Bowler, Nicolas Cassar, Loic Caudan, Genevieve Chabot, Natalie R. Cohen, Daniel Cron, Colomban De Vargas, John R. Dolan, Eric Douville, Amanda Elineau, J. Michel Flores, Jean Francois Ghiglione, Nils Haëntjens, Martin Hertau, Seth G. John, Rachel L. Kelly, Ilan Koren, Yajuan Lin, Dominique Marie, Clémentine Moulin, Yohann Moucherie, Stéphane Pesant, Marc Picheral, Julie Poulain, Mireille Pujo-Pay, Gilles Reverdin, Sarah Romac, Mathew B. Sullivan, Miri Trainic, Marc Tressol, Romain Troublé, Assaf Vardi, Christian R. Voolstra, Patrick Wincker, Sylvain Agostini, Bernard Banaigs, Emilie Boissin, Didier Forcioli, Paola Furla, Pierre E. Galand, Eric Gilson, Stéphanie Reynaud, Shinichi Sunagawa, Olivier P. Thomas, Rebecca Lisette Vega Thurber, Didier Zoccola, on behalf of Tara Pacific Consortium, Serge Planes, Denis Allemand and Eric Karsenti.

    Frontiers in Marine Science, 11 December 2019

    Doi: 10.3389/fmars.2019.00750

  • The Tara Pacific expedition: A pan-ecosystemic approach of the "-omics" complexity of coral reef holobionts across the Pacific Ocean

    Planes S, Allemand D, Agostini S, Banaigs B, Boissin E, Boss E, Bourdin G, Bowler C, Douville E, Flores JM, Forcioli D, Furla P, Galand PE, Ghiglione JF, Gilson E, Lombard F, Moulin C, Pesant S, Poulain J, Reynaud S, Romac S, Sullivan MB, Sunagawa S, Thomas OP, Troublé R, de Vargas C, Vega Thurber R, Voolstra CR, Wincker P, Zoccola D; Tara Pacific Consortium.

    PLoS Biol. 2019 Sep 23;17(9):e3000483. doi: 10.1371/journal.pbio.3000483. [Epub ahead of print]

    PMID: 31545807

  • The Landscape of L1 Retrotransposons in the Human Genome Is Shaped by Pre-insertion Sequence Biases and Post-insertion Selection.


    Sultana T*, van Essen D*, Siol O, Bailly-Bechet M, Philippe C, Zine El Aabidine A, Pioger L, Nigumann P, Saccani S, Andrau JC, Gilbert N, Cristofari G.

    Mol Cell. 2019 May 2;74(3):555-570

    (*equal contribution)

  • Shared molecular targets confer resistance over short and long evolutionary timescales

    Li J, Vázquez-García I, Persson K, González A, Yue JX, Barré B, Hall MN, Long A, Warringer J, Mustonen V, Liti G.

    Mol Biol Evol. 2019

    PMID: 30657986

  • The OncoAge Consortium: Linking Aging and Oncology from Bench to Bedside and Back Again.

    Hofman P, Ayache N, Barbry P, Barlaud M, Bel A, Blancou P, Checler F, Chevillard S, Cristofari G, Demory M, Esnault V, Falandry C, Gilson E, Guérin O, Glaichenhaus N, Guigay J, Ilié M, Mari B, Marquette CH, Paquis-Flucklinger V, Prate F, Saintigny P, Seitz-Polsky B, Skhiri T, Van Obberghen-Schilling E, Van Obberghen E, Yvan-Charvet L.

    Cancers (Basel). 2019 Feb 21;11(2):250. doi: 10.3390/cancers11020250

    PMID: 30795607

  • Tracing the cellular dynamics of sebaceous gland development in normal and perturbed states.

    Andersen MS, Hannezo E, Ulyanchenko S, Estrach S, Antoku Y, Pisano S, Boonekamp KE, Sendrup S, Maimets M, Pedersen MT, Johansen JV, Clement DL, Feral CC, Simons BD, Jensen KB.

    Nat Cell Biol. 2019 Aug;21(8):924-932. doi: 10.1038/s41556-019-0362-x. Epub 2019 Jul 29.

    PMID: 31358966
  • A novel variant m.8561C>T in the overlapping region of MT-ATP6 and MT-ATP8 in a child with early-onset severe neurological signs

    Fragaki K, Chaussenot A, Serre V, Acquaviva C, Bannwarth S, Rouzier C, Chabrol B, Paquis-Flucklinger V.

    Mol Genet Metab Rep. 2019 Nov 21;21:100543. doi: 10.1016/j.ymgmr.2019.100543. eCollection 2019 Dec.

    PMID: 31788426

  • NDUFS6 related Leigh syndrome: a case report and review of the literature

    Rouzier C, Chaussenot A, Fragaki K, Serre V, Ait-El-Mkadem S, Richelme C, Paquis-Flucklinger V, Bannwarth S.

    J Hum Genet. 2019 Jul;64(7):637-645. doi: 10.1038/s10038-019-0594-4. Epub 2019 Apr 4.

    PMID: 30948790
  • The Desire to Better Understand Older Adults with Solid Tumors to Improve Management: Assessment and Guided Interventions-The French PACA EST Cohort Experience.

    Boulahssass R, Gonfrier S, Champigny N, Lassalle S, François E, Hofman P, Guerin O.

    Cancers (Basel). 2019 Feb 7;11(2). pii: E192.

    PMID: 30736406

  • Inhibiting TRF1 upstream signaling pathways to target telomeres in cancer cells.

    Cherfils-Vicini J, Gilson E.

    EMBO Mol Med. 2019 Jul;11(7):e10845. doi: 10.15252/emmm.201910845. Epub 2019 Jun 13. PMID: 31273935

  • Ssu72 phosphatase is a conserved telomere replication terminator

    Escandell JM, Carvalho ES, Gallo-Fernandez M, Reis CC, Matmati S, Luís IM, Abreu IA, Coulon S, Ferreira MG.

    The EMBO journal. 2019;

    PMID: 30796050
  • The Zebrafish as an Emerging Model to Study DNA Damage in Aging, Cancer and Other Diseases.

    Cayuela ML, Claes KBM, Ferreira MG, Henriques CM, van Eeden F, Varga M, Vierstraete J, Mione MC.
    Frontiers in cell and developmental biology. 2019; 6:178.
    PMID: 30687705

  • Lysosomal acid ceramidase ASAH1 controls the transition between invasive and proliferative phenotype in melanoma cells.

    Leclerc J, Garandeau D, Pandiani C, Gaudel C, Bille K, Nottet N, Garcia V, Colosetti P, Pagnotta S, Bahadoran P, Tondeur G, Mograbi B, Dalle S, Caramel J, Levade T, Ballotti R, Andrieu-Abadie N, Bertolotto C.

    Oncogene. 2019 Feb;38(8):1282-1295.

    doi:10.1038/s41388-018-0500-0. Epub 2018 Sep 25.

    PMID: 30254208.

  • VEGFC acts as a double-edged sword in renal cell carcinoma aggressiveness.

    Ndiaye PD, Dufies M, Giuliano S, Douguet L, Grépin R, Durivault J, Lenormand P, Glisse N, Mintcheva J, Vouret-Craviari V, Mograbi B, Wurmser M, Ambrosetti D, Rioux-Leclercq N, Maire P, Pagès G.

    Theranostics. 2019 Jan 21;9(3):661-675.

    PMID: 30809300

  • Tumor-Stroma Mechanics Coordinate Amino Acid Availability to Sustain Tumor Growth and Malignancy.

    Bertero T, Oldham WM, Grasset EM, Bourget I, Boulter E, Pisano S, Hofman P, Bellvert F, Meneguzzi G, Bulavin DV, Estrach S, Feral CC, Chan SY, Bozec A, Gaggioli C.

    Cell Metab. 2019 Jan 8;29(1):124-140.e10.

    PMID: 30293773

  • The OncoAge Consortium: Linking Aging and Oncology from Bench to Bedside and Back Again

    Hofman P, Ayache N, Barbry P, Barlaud M, Bel A, Blancou P, Checler F, Chevillard S, Cristofari G, Demory M, Esnault V, Falandry C, Gilson E, Guérin O, Glaichenhaus N, Guigay J, Ilié M, Mari B, Marquette CH, Paquis-Flucklinger V, Prate F, Saintigny P, Seitz-Polsky B, Skhiri T, Van Obberghen-Schilling E, Van Obberghen E, Yvan-Charvet L.

    Cancers (Basel). 2019 Feb 21;11(2). pii: E250. doi: 10.3390/cancers11020250.

    PMID: 30795607

  • eKLIPse: a sensitive tool for the detection and quantification of mitochondrial DNA deletions from next-generation sequencing data

    Goudenège D, Bris C, Hoffmann V, Desquiret-Dumas V, Jardel C, Rucheton B, Bannwarth S, Paquis-Flucklinger V, Lebre AS, Colin E, Amati-Bonneau P, Bonneau D, Reynier P, Lenaers G, Procaccio V.

    Genet Med. 2019 Jun;21(6):1407-1416. 

    PMID: 30393377
  • Analysis of DNA-Protein Complexes by Atomic Force Microscopy Imaging: The Case of TRF2-Telomeric DNA Wrapping

    Pisano S, Gilson E.

    Methods Mol Biol. 2019;1886:75-97. doi: 10.1007/978-1-4939-8894-5_5.

    PMID: 30374863


  • TRF2 positively regulates SULF2 expression increasing VEGF-A release and activity in tumor microenvironment.

    Zizza P, Dinami R, Porru M, Cingolani C, Salvati E, Rizzo A, D'Angelo C, Petti E, Amoreo CA, Mottolese M, Sperduti I, Chambery A, Russo R, Ostano P, Chiorino G, Blandino G, Sacconi A, Cherfils-Vicini J, Leonetti C, Gilson E, Biroccio A.

    Nucleic Acids Res. 2019 Jan 30. doi: 10.1093/nar/gkz041

    PMID: 30698737

  • Thoracic oncology and tumor mutational burden: Towards new challenges for the pathologist?

    Hofman P.

    Ann Pathol (French). 2019 Jan 30. pii: S0242-6498(18)30193-7.

    PMID: 30711336


  • Petite Integration Factor 1 (PIF1) helicase deficiency increases weight gain in Western diet-fed female mice without increased inflammatory markers or decreased glucose clearance

    Belmonte FR, Dedousis N, Sipula I, Desai NA, Singhi AD, Chu Y, Zhang Y, Bannwarth S, Paquis-Flucklinger V, Harrington L, Shiva S, Jurczak MJ, O'Doherty RM, Kaufman BA.

    PLoS One. 2019 May 28;14(5):e0203101. doi: 10.1371/journal.pone.0203101. eCollection 2019.

    PMID: 31136580

  • Whole genome paired-end sequencing elucidates functional and phenotypic consequences of balanced chromosomal rearrangement in patients with developmental disorders

    Schluth-Bolard C, Diguet F, Chatron N, Rollat-Farnier PA, Bardel C, Afenjar A, Amblard F, Amiel J, Blesson S, Callier P, Capri Y, Collignon P, Cordier MP, Coubes C, Demeer B, Chaussenot A, Demurger F, Devillard F, Doco-Fenzy M, Dupont C, Dupont JM, Dupuis-Girod S, Faivre L, Gilbert-Dussardier B, Guerrot AM, Houlier M, Isidor B, Jaillard S, Joly-Hélas G, Kremer V, Lacombe D, Le Caignec C, Lebbar A, Lebrun M, Lesca G, Lespinasse J, Levy J, Malan V, Mathieu-Dramard M, Masson J, Masurel-Paulet A, Mignot C, Missirian C, Morice-Picard F, Moutton S, Nadeau G, Pebrel-Richard C, Odent S, Paquis-Flucklinger V, Pasquier L, Philip N, Plutino M, Pons L, Portnoï MF, Prieur F, Puechberty J, Putoux A, Rio M, Rooryck-Thambo C, Rossi M, Sarret C, Satre V, Siffroi JP, Till M, Touraine R, Toutain A, Toutain J, Valence S, Verloes A, Whalen S, Edery P, Tabet AC, Sanlaville D.

    J Med Genet. 2019 Aug;56(8):526-535

    PMID: 30923172
  • GAPDH Expression Predicts the Response to R-CHOP, the Tumor Metabolic Status, and the Response of DLBCL Patients to Metabolic Inhibitors

    Chiche J, Reverso-Meinietti J, Mouchotte A, Rubio-Patiño C, Mhaidly R, Villa E, Bossowski JP, Proics E, Grima-Reyes M, Paquet A, Fragaki K, Marchetti S, Briere J, Ambrosetti D, Michiels JF, Molina TJ, Copie-Bergman C, Lehmann-Che J, Peyrottes I, Peyrade F, de Kerviler E, Taillan B, Garnier G, Verhoeyen E, Paquis-Flucklinger V, Shintu L, Delwail V, Delpech-Debiais C, Delarue R, Bosly A, Petrella T, Brisou G, Nadel B, Barbry P, Mounier N, Thieblemont C, Ricci JE.

    Cell Metab. 2019 Jun 4;29(6):1243-1257.e10. 

    PMID: 30827861
  • FSHD1 and FSHD2 form a disease continuum.

    Sacconi S, Briand-Suleau A, Gros M, Baudoin C, Lemmers RJLF, Rondeau S, Lagha N, Nigumann P, Cambieri C, Puma A, Chapon F, Stojkovic T, Vial C, Bouhour F, Cao M, Pegoraro E, Petiot P, Behin A, Marc B, Eymard B, Echaniz-Laguna A, Laforet P, Salviati L, Jeanpierre M, Cristofari G*, van der Maarel SM*. [*co-last authors]

    Neurology. 2019 May 7;92(19):e2273-e2285. doi: 10.1212/WNL.0000000000007456

    PMID: 30979860

  • The many faced symbiotic snakelocks anemone (Anemonia viridis, Anthozoa): Host and symbiont genetic differentiation among colour morphs

    Porro B, Mallien C, Hume BCC, Pey A, Aubin E, Christen R, Voolstra CR, Furla P, Forcioli D.

    Heredity. 2019 Sep 16.

    PMID: 31527783

  • The landscape of L1 retrotransposons in the human genome is shaped by pre-insertion sequence biases and post-insertion selection.

    Sultana T*, van Essen D*, Siol O, Bailly-Bechet M, Philippe C, Zine El Aabidine A, Pioger L, Nigumann P, Saccani S, Andrau JC, Gilbert N, Cristofari G. [*co-first authors]

    Mol Cell. 2019 May 2;74(3):555-570.e7. doi: 10.1016/j.molcel.2019.02.036

    PMID: 30956044


  • Liquid biopsy in the era of immuno-oncology: is it ready for prime-time use for cancer patients?

    Hofman P, Heeke S, Alix-Panabières C, Pantel K.

    Ann Oncol. 2019 Sep 1;30(9):1448-1459. doi: 10.1093/annonc/mdz196.

    PMID:  31228184

  • Alternative splicing of P2RX7 pre-messenger RNA in health and diseases: Myth or reality?

    Benzaquen J, Heeke S, Janho Dit Hreich S, Douguet L, Marquette CH, Hofman P, Vouret-Craviari V.

    Biomed J. 2019 Jun;42(3):141-154. doi: 10.1016/ Epub 2019 Jul 15. Review.

    PMID: 31466708

  • Prognostic and predictive role of CD8 and PD-L1 determination in lung tumor tissue of patients under anti-PD-1 therapy. (Correction)

    Fumet JD, Richard C, Ledys F, Klopfenstein Q, Joubert P, Routy B, Truntzer C, Gagné A, Hamel MA, Guimaraes CF, Coudert B, Arnould L, Favier L, Lagrange A, Ladoire S, Saintigny P, Ortiz-Cuaran S, Perol M, Foucher P, Hofman P, Ilie M, Chevrier S, Boidot R, Derangere V, Ghiringhelli F.

    Br J Cancer. 2019 Jul;121(3):283. doi: 10.1038/s41416-019-0512-8.

    PMID: 31235866

  • Never Travel Alone: The Crosstalk of Circulating Tumor Cells and the Blood Microenvironment.

    Heeke S, Mograbi B, Alix-Panabières C, Hofman P.

    Cells. 2019 Jul 13;8(7). pii: E714. doi: 10.3390/cells8070714. Review.

    PMID: 31337010

  • The Long Noncoding RNA DNM3OS Is a Reservoir of FibromiRs with Major Functions in Lung Fibroblast Response to TGF-β and Pulmonary Fibrosis.

    Savary G, Dewaeles E, Diazzi S, Buscot M, Nottet N, Fassy J, Courcot E, Henaoui IS, Lemaire J, Martis N, Van der Hauwaert C, Pons N, Magnone V, Leroy S, Hofman V, Plantier L, Lebrigand K, Paquet A, Lino Cardenas CL, Vassaux G, Hofman P, Günther A, Crestani B, Wallaert B, Rezzonico R, Brousseau T, Glowacki F, Bellusci S, Perrais M, Broly F, Barbry P, Marquette CH, Cauffiez C, Mari B, Pottier N.

    Am J Respir Crit Care Med. 2019 Jul 15;200(2):184-198. doi: 10.1164/rccm.201807-1237OC.

    PMID: 30964696

  • DNAshell Protects DNA Stored at Room Temperature for Downstream Next-Generation Sequencing Studies.

    Washetine K, Heeke S, Ribeyre C, Bourreau C, Normand C, Blons H, Laurent-Puig P, Mulot C, Clermont D, David M, Clément B, Dagher G, Hofman P.

    Biopreserv Biobank. 2019 Aug;17(4):352-354. doi: 10.1089/bio.2018.0129. Epub 2019 Mar 26. No abstract available.

    PMID: 30912674

  • Resistances to EGFR tyrosine kinase inhibitors in lung cancer-how to routinely track them in a molecular pathology laboratory?

    Hofman V, Hofman P.

    J Thorac Dis. 2019 Jan;11(Suppl 1):S65-S70. doi: 10.21037/jtd.2018.11.76. Review.

    PMID:  30775029



  • In-house Implementation of Tumor Mutational Burden Testing to Predict Durable Clinical Benefit in Non-small Cell Lung Cancer and Melanoma Patients.

    Heeke S, Benzaquen J, Long-Mira E, Audelan B, Lespinet V, Bordone O, Lalvée S, Zahaf K, Poudenx M, Humbert O, Montaudié H, Dugourd PM, Chassang M, Passeron T, Delingette H, Marquette CH, Hofman V, Stenzinger A, Ilié M, Hofman P.

    Cancers (Basel). 2019 Aug 29;11(9). pii: E1271. doi: 10.3390/cancers11091271.

    PMID: 31470674



  • First-line immunotherapy for patients with advanced stage or metastatic non-small cell lung cancer…finally what threshold of PD-L1 expression on tumor cells?

    Hofman P.

    Transl Lung Cancer Res. 2019 Oct;8(5):728-730. doi: 10.21037/tlcr.2019.04.18. No abstract available.

    PMID: 31737511

  • Toward precision medicine based on the molecular landscape of carcinoma in situ of the bronchus: is it realistic for patients with pre-invasive lung disease?

    Hofman P.

    J Thorac Dis. 2019 May;11(Suppl 9):S1286-S1288. doi: 10.21037/jtd.2019.04.87. No abstract available.

    PMID: 31245111

  • The nuclear hypoxia-regulated NLUCAT1 long non-coding RNA contributes to an aggressive phenotype in lung adenocarcinoma through regulation of oxidative stress.

    Moreno Leon L, Gautier M, Allan R, Ilié M, Nottet N, Pons N, Paquet A, Lebrigand K, Truchi M, Fassy J, Magnone V, Kinnebrew G, Radovich M, Cheok MH, Barbry P, Vassaux G, Marquette CH, Ponzio G, Ivan M, Pottier N, Hofman P, Mari B, Rezzonico R.

    Oncogene. 2019 Nov;38(46):7146-7165. doi: 10.1038/s41388-019-0935-y. Epub 2019 Aug 15.

    PMID: 31417181

  • GC content shapes mRNA storage and decay in human cells.

    Courel M, Clément Y, Bossevain C, Foretek D, Vidal Cruchez O, Yi Z, Bénard M, Benassy MN, Kress M, Vindry C, Ernoult-Lange M, Antoniewski C, Morillon A, Brest P, Hubstenberger A, Roest Crollius H, Standart N, Weil D.

    Elife. 2019 Dec 19;8. pii: e49708. doi: 10.7554/eLife.49708.

    PMID: 31855182

  • Germinal immunogenetics as a predictive factor for immunotherapy.

    Refae S, Gal J, Brest P, Milano G.

    Crit Rev Oncol Hematol. 2019 Sep;141:146-152. doi: 10.1016/j.critrevonc.2019.06.013. Epub 2019 Jun 28. Review.

    PMID: 31301542

  • Recent advances in the molecular landscape of lung neuroendocrine tumors

    Pelosi G, Bianchi F, Hofman P, Pattini L, Ströbel P, Calabrese F, Naheed S, Holden C, Cave J, Bohnenberger H, Dinter H, Harari S, Albini A, Sonzogni A, Papotti M, Volante M, Ottensmeier CH.
    Expert Rev Mol Diagn. 2019 Apr;19(4):281-297. doi: 10.1080/14737159.2019.1595593. Epub 2019 Mar 27. Review.
    PMID: 30900485

  • EGFR Mutation Analysis in Non-small Cell Lung Carcinoma from Tissue Samples Using the Fully Automated Idylla™ qPCR System.

    Heeke S, Hofman P. 

    Methods Mol Biol. 2019;2054:147‐155.


    PMID: 31482454

  • Double minute chromosomes harboring MDM2 amplification in a pediatric atypical lipomatous tumor.

    Dadone-Montaudié B, Burel-Vandenbos F, Soler C, Rosello O, Boyer C, Fabas T, Bianchini L, Pedeutour F.

    Genes Chromosomes Cancer, 2019, 58:673-679.

    doi: 10.1002/gcc.22754

    PMID: 30887579

  • Cellular Angiofibroma: Case Report of a Unique Subungual Presentation

    Perrin C, Cannata GE, Pedeutour F, Dadone-Montaudié B, Ambrosetti D.

    Acta Derm Venereol. 2019 Sep 1;99(10):915-916.

    doi: 10.2340/00015555-3152

    PMID: 30809688

  • Companion diagnostic tests for treatment of lung cancer patients: what are the current and future challenges?

    Hofman P, Barlesi F.

    Expert Rev Mol Diagn. 2019 May;19(5):429-438. doi: 10.1080/14737159.2019.1611426. Epub 2019 May 6.

    PMID: 31018102

  • Integrative and comparative genomic analyses identify clinically relevant pulmonary carcinoid groups and unveil the supra-carcinoids.

    Alcala N, Leblay N, Gabriel AAG, Mangiante L, Hervas D, Giffon T, Sertier AS, Ferrari A, Derks J, Ghantous A, Delhomme TM, Chabrier A, Cuenin C, Abedi-Ardekani B, Boland A, Olaso R, Meyer V, Altmuller J, Le Calvez-Kelm F, Durand G, Voegele C, Boyault S, Moonen L, Lemaitre N, Lorimier P, Toffart AC, Soltermann A, Clement JH, Saenger J, Field JK, Brevet M, Blanc-Fournier C, Galateau-Salle F, Le Stang N, Russell PA, Wright G, Sozzi G, Pastorino U, Lacomme S, Vignaud JM, Hofman V, Hofman P, Brustugun OT, Lund-Iversen M, Thomas de Montpreville V, Muscarella LA, Graziano P, Popper H, Stojsic J, Deleuze JF, Herceg Z, Viari A, Nuernberg P, Pelosi G, Dingemans AMC, Milione M, Roz L, Brcic L, Volante M, Papotti MG, Caux C, Sandoval J, Hernandez-Vargas H, Brambilla E, Speel EJM, Girard N, Lantuejoul S, McKay JD, Foll M, Fernandez-Cuesta L.

    Nat Commun. 2019 Aug 20;10(1):3407. doi: 10.1038/s41467-019-11276-9.

    PMID: 31431620

  • Tumor banks and complex data management: Current and future challenges.

    Hofman P, Dagher G, Laurent-Puig P, Marquette CH, Barlesi F, Bibeau F, Clément B.

    Ann Pathol. 2019 Apr;39(2):137-143. doi: 10.1016/j.annpat.2019.01.017. Epub 2019 Feb 25. Review. French.

    PMID: 30819623

  • Recent advances in the molecular landscape of lung neuroendocrine tumors.

    Pelosi G, Bianchi F, Hofman P, Pattini L, Ströbel P, Calabrese F, Naheed S, Holden C, Cave J, Bohnenberger H, Dinter H, Harari S, Albini A, Sonzogni A, Papotti M, Volante M, Ottensmeier CH.

    Expert Rev Mol Diagn. 2019 Apr;19(4):281-297. doi: 10.1080/14737159.2019.1595593. Epub 2019 Mar 27.

    PMID: 30900485

  • Advances in theranostic biomarkers for lung cancer from clinical to molecular pathology.

    Hofman P.

    J Thorac Dis. 2019 Jan;11(Suppl 1):S1-S2. doi: 10.21037/jtd.2018.10.28. No abstract available.

    PMID: 30775022

  • The challenges of evaluating predictive biomarkers using small biopsy tissue samples and liquid biopsies from non-small cell lung cancer patients.

    Hofman P. 

    J Thorac Dis. 2019 Jan;11(Suppl 1):S57-S64. doi: 10.21037/jtd.2018.11.85. Review.

    PMID: 30775028

  • Circulating free tumor DNA in non-small cell lung cancer (NSCLC): clinical application and future perspectives.

    Herbreteau G, Vallée A, Charpentier S, Normanno N, Hofman P, Denis MG.

    J Thorac Dis. 2019 Jan;11(Suppl 1):S113-S126. doi: 10.21037/jtd.2018.12.18. Review.

    PMID: 30775034

  • Circulating Tumor Cell Detection in Lung Cancer: But to What End?

    Hofman V, Heeke S, Marquette CH, Ilié M, Hofman P.

    Cancers (Basel). 2019 Feb 23;11(2). pii: E262. doi: 10.3390/cancers11020262. Review.

    PMID: 30813420

  • Multiplexed Immunohistochemistry for Molecular and Immune Profiling in Lung Cancer-Just About Ready for Prime-Time?

    Hofman P, Badoual C, Henderson F, Berland L, Hamila M, Long-Mira E, Lassalle S, Roussel H, Hofman V, Tartour E, Ilié M.

    Cancers (Basel). 2019 Feb 27;11(3). pii: E283. doi: 10.3390/cancers11030283. Review.

    PMID: 30818873

  • The Molecular Pathology of Eye Tumors: A 2019 Update Main Interests for Routine Clinical Practice.

    Nahon-Esteve S, Martel A, Maschi C, Caujolle JP, Baillif S, Lassalle S, Hofman P.

    Curr Mol Med. 2019;19(9):632-664. doi: 10.2174/1566524019666190726161044.

    PMID: 31418658

  • Is the onset of adverse effects of immunotherapy always bad news for the patients…?-certainly not!

    Hofman P.

    Ann Transl Med. 2019 Mar;7(Suppl 1):S5. doi: 10.21037/atm.2019.01.14. No abstract available.

    PMID: 31032286

  • Are There New Biomarkers in Tissue and Liquid Biopsies for the Early Detection of Non-Small Cell Lung Cancer?

    Calabrese F, Lunardi F, Pezzuto F, Fortarezza F, Vuljan SE, Marquette C, Hofman P.

    J Clin Med. 2019 Mar 26;8(3). pii: E414. doi: 10.3390/jcm8030414. Review.

    PMID: 30917582

  • PD1/PD-L1 inhibitor treatment for late stage non-small cell lung carcinoma, sometimes…does more harm than good!

    Hofman P.

    J Thorac Dis. 2019 Mar;11(Suppl 3):S396-S398. doi: 10.21037/jtd.2018.11.140. No abstract available.

    PMID: 30997230

  • Lung Cancer Screening, Towards a Multidimensional Approach: Why and How?

    Benzaquen J, Boutros J, Marquette C, Delingette H, Hofman P.

    Cancers (Basel). 2019 Feb 12;11(2). pii: E212. doi: 10.3390/cancers11020212. Review.

    PMID: 30759893

  • Programmed death ligand 1 immunohistochemistry in non-small cell lung carcinoma.

    Lantuejoul S, Damotte D, Hofman V, Adam J.

    J Thorac Dis. 2019 Jan;11(Suppl 1):S89-S101. doi: 10.21037/jtd.2018.12.103. Review.

    PMID: 30775032

  • Prognostic and predictive role of CD8 and PD-L1 determination in lung tumor tissue of patients under anti-PD-1 therapy.

    Fumet JD, Richard C, Ledys F, Klopfenstein Q, Joubert P, Routy B, Truntzer C, Gagné A, Hamel MA, Guimaraes CF, Coudert B, Arnould L, Favier L, Lagrange A, Ladoire S, Saintigny P, Ortiz-Cuaran S, Perol M, Foucher P, Hofman P, Ilie M, Chevrier S, Boidot R, Derangere V, Ghiringhelli F.

    Br J Cancer. 2018 Oct;119(8):950-960.

    doi: 10.1038/s41416-018-0220-9. Epub 2018 Oct 15.

    PMID: 30318514.

  • Use of the 22C3 anti-programmed death-ligand 1 antibody to determine programmed death-ligand 1 expression in cytology samples obtained from non-small cell lung cancer patients.

    Ilie M, Juco J, Huang L, Hofman V, Khambata-Ford S, Hofman P.

    Cancer Cytopathol. 2018 Apr;126(4):264-274.

    doi: 10.1002/cncy.21977. Epub 2018 Feb 7.

    PMID: 29411536.


  • [Practices in infectious pathology in France in 2015. Results of the national survey].

    Tauziède-Espariat A, Chrétien F, Jouvion G, Alde-Biassette H, Hofman P.

    Ann Pathol. 2018 Feb;38(1):55-63.

    doi: 10.1016/j.annpat.2017.12.002. Epub 2018 Jan 7. French.

    PMID: 29317100.

  • Use of the Ion PGM and the GeneReader NGS Systems in Daily Routine Practice for Advanced Lung Adenocarcinoma Patients: A Practical Point of View Reporting a  Comparative Study and Assessment of 90 Patients.

    Heeke S, Hofman V, Long-Mira E, Lespinet V, Lalvée S, Bordone O, Ribeyre C, Tanga V, Benzaquen J, Leroy S, Cohen C, Mouroux J, Marquette CH, Ilié M, Hofman P.

    Cancers (Basel). 2018 Mar 21;10(4). pii: E88.

    doi: 10.3390/cancers10040088.

    PMID: 29561830;

    PubMed Central PMCID: PMC5923343.

  • Rapid decay  of engulfed extracellular miRNA by XRN1 exonuclease promotes transient epithelial-mesenchymal transition.

    Zangari J, Ilie M, Rouaud F, Signetti L, Ohanna M, Didier R, Roméo B, Goldoni D, Nottet N, Staedel C, Gal J, Mari B, Mograbi B, Hofman P, Brest P.

    Nucleic Acids Res. 2018 Apr 20;46(7):3813-3814.

    doi: 10.1093/nar/gky213.

    PMID: 29562367;

    PubMed Central PMCID: PMC5909457.

  • Monitoring BRAF and NRAS mutations with cell-free circulating tumor DNA from metastatic melanoma patients.

    Long-Mira E, Ilie M, Chamorey E, Leduff-Blanc F, Montaudié H, Tanga V, Allégra M, Lespinet-Fabre V, Bordone O, Bonnetaud C, Schiappa R, Butori C, Bence C, Lacour JP, Hofman V, Hofman P.

    Oncotarget. 2018 Nov 16;9(90):36238-36249.

    doi: 10.18632/oncotarget.26343. eCollection 2018 Nov 16.

    PMID: 30546839;

    PubMed Central PMCID: PMC6281416.

  • Tumor mutational burden assessment as a predictive biomarker for immunotherapy in lung cancer patients: getting ready for prime-time or not?

    Heeke S, Hofman P.

    Transl Lung Cancer Res. 2018 Dec;7(6):631-638.

    doi: 10.21037/tlcr.2018.08.04. Review.

    PMID: 30505707;

    PubMed Central PMCID: PMC6249624.

  • Spotlight on tumor mutational burden in patients with non-small cell lung carcinoma.

    Ilie M, Hofman P.

    Transl Lung Cancer Res. 2018 Dec;7(6):614-615.

    doi: 10.21037/tlcr.2018.08.06.

    PMID: 30505705;

    PubMed Central PMCID: PMC6249616.

  • [Next generation biobanking: the challenge of data].

    Dagher G, Lavitrano ML, Hofman P.

    Med Sci (Paris). 2018 Oct;34(10):849-851.

    doi: 10.1051/medsci/2018203.  Epub 2018 Nov 19. French.

    PMID: 30451660.

  • Using 22C3 Anti-PD-L1 Antibody Concentrate on Biopsy and Cytology Samples from Non-small Cell Lung Cancer Patients.

    Ilié M, Ngo-Mai M, Long-Mira E, Lassalle S, Butori C, Bence C, Hamila M, Hofman V, Hofman P.

    J Vis Exp. 2018 Sep 25;(139).

    doi: 10.3791/58082.

    PMID: 30320751;

    PubMed Central PMCID: PMC6235290.

  • Multi-laboratory proficiency testing of clinical cancer genomic profiling by next-generation sequencing.

    Zhong Q, Wagner U, Kurt H, Molinari F, Cathomas G, Komminoth P, Barman-Aksözen J, Schneider-Yin X, Rey JP, Vassella E, Rogel U, Diebold J, McKee  T, Jochum W, Kashofer K, Hofman P, Zischka M, Moch H, Rechsteiner M, Wild PJ.

    Pathol Res Pract. 2018 Jul;214(7):957-963.

    doi: 10.1016/j.prp.2018.05.020. Epub 2018 May 22.

    PMID: 29807778.

  • Brain-derived neurotrophic factor, a new soluble biomarker for malignant pleural mesothelioma involved in angiogenesis.

    Smeele P, d'Almeida SM, Meiller C, Chéné AL, Liddell C, Cellerin L, Montagne  F, Deshayes S, Benziane S, Copin MC, Hofman P, Le Pimpec-Barthes F, Porte H, Scherpereel A, Grégoire M, Jean D, Blanquart C.

    Mol Cancer. 2018 Oct 11;17(1):148.

    doi: 10.1186/s12943-018-0891-0. 

    PMID: 30309369;

    PubMed Central PMCID: PMC6180566.

  • Effect of mutant variants of the KRAS gene on PD-L1 expression and on the immune microenvironment and association with clinical outcome in lung adenocarcinoma patients.

    Falk AT, Yazbeck N, Guibert N, Chamorey E, Paquet A, Ribeyre L, Bence C, Zahaf K, Leroy S, Marquette CH, Cohen C, Mograbi B, Mazières J, Hofman V, Brest P, Hofman P, Ilié M.

    Lung Cancer. 2018 Jul;121:70-75.

    doi: 10.1016/j.lungcan.2018.05.009. Epub 2018 May 26.

    PMID: 29858030.

  • ALK IHC and FISH discordant results in patients with NSCLC and treatment response: for discussion  of the question-to treat or not to treat?

    Cabillic F, Hofman P, Ilie M, Peled N, Hochmair M, Dietel M, Von Laffert M, Gosney JR, Lopez-Rios F, Erb G, Schalles U, Barlesi F.

    ESMO Open. 2018 Sep 17;3(6):e000419.

    doi: 10.1136/esmoopen-2018-000419. eCollection 2018.

    PMID: 30245863;

    PubMed Central PMCID: PMC6144904.

  • Chromogenic Multiplex Immunohistochemistry Reveals Modulation of the Immune Microenvironment Associated with Survival in Elderly Patients with Lung Adenocarcinoma.

    Ilié M, Beaulande M, Ben Hadj S, Chamorey E, Schiappa R, Long-Mira E, Lassalle S, Butori C, Cohen C, Leroy S, Guérin O, Mouroux J, Marquette CH, Pomerol JF, Erb G, Hofman V, Hofman P.

    Cancers (Basel). 2018 Sep 13;10(9). pii: E326.

    doi: 10.3390/cancers10090326.

    PMID: 30216999;

    PubMed Central PMCID: PMC6162494.

  • Matrix Stiffening and EGFR Cooperate to Promote the Collective Invasion of Cancer Cells.

    Grasset EM, Bertero T, Bozec A, Friard J, Bourget I, Pisano S, Lecacheur M, Maiel M, Bailleux C, Emelyanov A, Ilie M, Hofman P, Meneguzzi G, Duranton C, Bulavin DV, Gaggioli C.

    Cancer Res. 2018 Sep 15;78(18):5229-5242.

    doi: 10.1158/0008-5472.CAN-18-0601. Epub 2018 Jul 19.

    PMID: 30026329.

  • Pivotal role of NAMPT in the switch of melanoma cells toward an invasive and drug-resistant phenotype.

    Ohanna M, Cerezo M, Nottet N, Bille K, Didier R, Beranger G, Mograbi B, Rocchi S, Yvan-Charvet L, Ballotti R, Bertolotto C.

    Genes Dev. 2018 Mar 1;32(5-6):448-461. doi: 10.1101/gad.305854.117. Epub 2018 Mar 22.

    PMID: 29567766;

    PubMed Central PMCID: PMC5900716.

  • Single-cell genetic analysis validates cytopathological identification of circulating cancer cells in patients with clear cell renal cell carcinoma.

    Broncy L, Njima BB, Méjean A, Béroud C, Romdhane KB, Ilie M, Hofman V, Muret  J, Hofman P, Bouhamed HC, Paterlini-Bréchot AP.

    Oncotarget. 2018 Apr 13;9(28):20058-20074. 

    doi: 10.18632/oncotarget.25102. eCollection 2018 Apr 13.

    PMID: 29732003;

    PubMed Central PMCID: PMC5929446.

  • E2F1 inhibition mediates cell death of metastatic melanoma.

    Rouaud F, Hamouda-Tekaya N, Cerezo M, Abbe P, Zangari J, Hofman V, Ohanna M,  Mograbi B, El-Hachem N, Benfodda Z, Lebeau A, Tulic MK, Hofman P, Bertolotto C, Passeron T, Annicotte JS, Ballotti R, Rocchi S.

    Cell Death Dis. 2018 May 1;9(5):527.

    doi: 10.1038/s41419-018-0566-1.

    PMID: 29743521;

    PubMed Central PMCID: PMC5943238.

  • [Focus on clinical and pathological management of conjunctival melanocytic tumors].

    Lassalle S, Caujolle JP, Leger F, Maschi C, Gastaud L, Nahon-Esteve S, Thariat J, Baillif S, Hofman P.

    Ann Pathol. 2018 Jun;38(3):153-163.

    doi: 10.1016/j.annpat.2018.03.006. Epub 2018 May 24. Review. French.

    PMID: 29803361.

  • Establishing a Dedicated Lung Cancer Biobank at the University Center Hospital of Nice (France). Why and How?

    Washetine K, Heeke S, Bonnetaud C, Kara-Borni M, Ilié M, Lassalle S, Butori C, Long-Mira E, Marquette CH, Cohen C, Mouroux J, Selva E, Tanga V, Bence C, Félix JM, Gazoppi L, Skhiri T, Gormally E, Boucher P, Clément B, Dagher G, Hofman V, Hofman P.

    Cancers (Basel). 2018 Jun 29;10(7). pii: E220.

    doi: 10.3390/cancers10070220.

    PMID: 29966305;

    PubMed  Central PMCID: PMC6070810.

  • Ensuring the Safety and Security of Frozen Lung Cancer Tissue Collections through the Encapsulation of Dried DNA.

    Washetine K, Kara-Borni M, Heeke S, Bonnetaud C, Félix JM, Ribeyre L, Bence C, Ilié M, Bordone O, Pedro M, Maitre P, Tanga V, Gormally E, Mossuz P, Lorimier  P, Marquette CH, Mouroux J, Cohen C, Lassalle S, Long-Mira E, Clément B, Dagher G, Hofman V, Hofman P.

    Cancers (Basel). 2018  Jun 11;10(6). pii: E195.

    doi: 10.3390/cancers10060195.

    PMID: 29891792;

    PubMed Central PMCID: PMC6025404.

  • Automated chromogenic multiplexed immunohistochemistry assay for diagnosis and predictive biomarker testing in non-small cell lung cancer.

    Ilie M, Beaulande M, Hamila M, Erb G, Hofman V, Hofman P.

    Lung Cancer. 2018 Oct;124:90-94.

    doi: 10.1016/j.lungcan.2018.07.037. Epub 2018 Jul 31.

    PMID: 30268486.

  • eKLIPse: a sensitive tool for the detection and quantification of mitochondrial DNA deletions from next-generation sequencing data

    Goudenège D, Bris C, Hoffmann V, Desquiret-Dumas V, Jardel C, Rucheton B, Bannwarth S, Paquis-Flucklinger V, Lebre AS, Colin E, Amati-Bonneau P, Bonneau D, Reynier P, Lenaers G, Procaccio V.

    Genet Med. 2018 Nov 5. doi: 10.1038/s41436-018-0350-8.

    PMID: 30393377 

  • Long-read sequencing data analysis for yeasts

    Yue JX, Liti G.

    Nat Protoc. 2018 13:1213-1231.

    PMID: 29725120


  • Genome evolution across 1,011 Saccharomyces cerevisiae isolates

    Peter J*, De Chiara M*, Friedrich A, Yue JX, Pflieger D, Bergström A, Sigwalt A, Barre B, Freel K, Llored A, Cruaud C, Labadie K, Aury JM, Istace B, Lebrigand K, Barbry P, Engelen S, Lemainque A, Wincker P, Liti G@, Schacherer J@.

    Nature. 2018 556:339-344.
    PMID: 29643504

    *co-first authors, @co-senior authors

  • Tetrad analysis in plants and fungi finds large differences in gene conversion rates but no GC bias

    Liu H, Huang J, Sun X, Li J, Hu Y, Yu L, Liti G, Tian D, Hurst LD, Yang S.

    Nat Ecol Evol. 2018 2:164-173.

    PMID: 29158556

  • Inflammatory facioscapulohumeral muscular dystrophy type 2 in 18p deletion syndrome.

    Renard D, Taieb G, Garibaldi M, Maues De Paula A, Bernard R, Lagha N, Cristofari G, Vovan C, Chaix C, Lévy N, Khau Van Kien P, Sacconi S.

    Am J Med Genet A. 2018 Aug;176(8):1760-1763.

    PMID: 30055030
  • HIV-1 Vpr and p21 restrict LINE-1 mobility.

    Kawano K*, Doucet AJ*, Ueno M, Kariya R, An W, Marzetta F, Kuroki M, Turelli P, Sukegawa S, Okada S, Strebel K, Trono D, Ariumi Y. [*co-first authors]

    Nucleic Acids Res. 2018 Sep 19;46(16):8454-8470.

    PMID: 30085096
  • Alternative PDGFD rearrangements in dermatofibrosarcomas protuberans without PDGFB fusions.

    Dadone-Montaudié B, Alberti L, Duc A, Delespaul L, Lesluyes T, Pérot G, Lançon A, Paindavoine S, Di Mauro I, Blay JY, de la Fouchardière A, Chibon F, Karanian M, MacGrogan G, Kubiniek V, Keslair F, Cardot-Leccia N, Michot A, Perrin V, Zekri Y, Coindre JM, Tirode F, Pedeutour F, Ranchère-Vince D, Le Loarer F, Pissaloux D.

    Mod Pathol. 2018 Nov;31(11):1683-1693. doi: 10.1038/s41379-018-0089-4. Epub 2018 Jun 28.

    PMID: 29955147
  • Microsatellite instability associated with durable complete response to PD-L1 inhibitor in head and neck squamous cell carcinoma.

    Tardy MP, Di Mauro I, Ebran N, Refae S, Bozec A, Benezery K, Peyrade F, Guigay J, Sudaka-Bahadoran A, Badoual C, Pedeutour F, Saada-Bouzid E.

    Oral Oncol. 2018 May;80:104-107. doi: 10.1016/j.oraloncology.2018.04.001. Epub 2018 Apr 7. No abstract available.

    PMID: 29631799
  • Comprehensive study of three novel cases of TFEB-amplified renal cell carcinoma and review of the literature: Evidence for a specific entity with poor outcome.

    Mendel L, Ambrosetti D, Bodokh Y, Ngo-Mai M, Durand M, Simbsler-Michel C, Delhorbe M, Amiel J, Pedeutour F.

    Genes Chromosomes Cancer. 2018 Mar;57(3):99-113. doi: 10.1002/gcc.22513. Epub 2017 Dec 20. Review.

    PMID: 29127730
  • The Hidden Genomic and Transcriptomic Plasticity of Giant Marker Chromosomes in Cancer.

    Macchia G, Severgnini M, Purgato S, Tolomeo D, Casciaro H, Cifola I, L'Abbate A, Loverro A, Palumbo O, Carella M, Bianchini L, Perini G, De Bellis G, Mertens F, Rocchi M, Storlazzi CT.

    Genetics. 2018 Mar;208(3):951-961. doi: 10.1534/genetics.117.300552. Epub 2017 Dec 26.

    PMID: 29279323
  • ALK-TPM3 rearrangement in adult renal cell carcinoma: Report of a new case showing loss of chromosome 3 and literature review.

    Bodokh Y, Ambrosetti D, Kubiniek V, Tibi B, Durand M, Amiel J, Pertuit M, Barlier A, Pedeutour F.

    Cancer Genet. 2018 Feb;221:31-37. doi: 10.1016/j.cancergen.2017.11.010. Epub 2017 Dec 12. Review.

    PMID: 29405994
  • DOCK4 promotes loss of proliferation in glioblastoma progenitor cells through nuclear beta-catenin accumulation and subsequent miR-302-367 cluster expression.

    Debruyne DN, Turchi L, Burel-Vandenbos F, Fareh M, Almairac F, Virolle V, Figarella-Branger D, Baeza-Kallee N, Lagadec P, Kubiniek V, Paquis P, Fontaine D, Junier MP, Chneiweiss H, Virolle T.

    Oncogene. 2018 Jan 11;37(2):241-254. doi: 10.1038/onc.2017.323. Epub 2017 Sep 18.

    PMID: 28925399
  • Three-Dimensional Cell Culture Conditions Affect the Proteome of Cancer-Associated Fibroblasts.

    Tölle RC, Gaggioli C, Dengjel J.

    J Proteome Res. 2018 Aug 3;17(8):2780-2789. doi: 10.1021/acs.jproteome.8b00237. Epub 2018 Jul 23.

    PMID: 29989826
  • Myopathy with MTCYB mutation mimicking Multiple Acyl-CoA Dehydrogenase Deficiency

    Kaphan E, Bou Ali H, Gastaldi M, Acquaviva C, Vianey-Saban C, Rouzier C, Fragaki K, Bannwarth S, Paquis-Flucklinger V, Romero N, Behin A, Lombès A, Jardel C, Rigal O, Laforêt P.

    Rev Neurol (Paris). 2018 Dec;174(10):731-735.

    PMID: 30318261

  • Genome-wide Control of Heterochromatin Replication by the Telomere Capping Protein TRF2 Mol Cell. 2018 May 3;70(3):449-461.e5. doi: 10.1016

    Mendez-Bermudez A, Lototska L, Bauwens S, Giraud-Panis MJ, Croce O, Jamet K, Irizar A, Mowinckel M, Koundrioukoff S, Nottet N, Almouzni G, Teulade-Fichou MP, Schertzer M, Perderiset M, Londoño-Vallejo A, Debatisse M, Gilson E, Ye J.

    Mol Cell. 2018 May 3;70(3):449-461.e5. doi: 10.1016

    PMID: 29727617


  • Yeast chromosome numbers minimized using genome editing

    Liti G

    Nature. 2018; 560:317-318.

    PMID: 30097656


  • Dermal Fibroblast SLC3A2 Deficiency Leads to Premature Aging and Loss of Epithelial Homeostasis

    J Invest Dermatol. 2018 Dec;138(12):2511-2521. doi: 10.1016/j.jid.2018.05.026. Epub 2018 Jun 12.

    PMID: 29906411
  • TRFH domain: at the root of telomere protein evolution?

    Panis MJ, Ye J, Gilson E.

    Cell Res. 2018 Jan;28(1):7-8

    PMID: 29192673



  • Cell metabolism regulates integrin mechanosensing via an SLC3A2-dependent sphingolipid biosynthesis pathway

    Nat Commun. 2018 Nov 19;9(1):4862. doi: 10.1038/s41467-018-07268-w.

    PMID: 30451822
  • How does an animal behave like a plant? Physiological and molecular adaptations of zooxanthellae and their hosts to symbiosis

    Allemand D, Furla P.

    C R Biol. 2018 May - Jun;341(5):276-280.

    PMID: 29650460

  • NvERTx: a gene expression database to compare embryogenesis and regeneration in the sea anemone Nematostella vectensis

    Warner J, Guérlais V, Amiel RA, JohnstonH, Nedoncelle K & Röttinger E


    PMID: 29739837

  • Cnidarian primary cell culture as a tool to investigate the effect of thermal stress at the cellular level

    Ventura P, Toullec G, Fricano C, Chapron L, Meunier V, Röttinger E, Furla P, Barnay-Verdier S.

    Marine Biotechnology. 20(2):144-154

    PMID: 29313151

  • Loss of MICOS complex integrity and mitochondrial damage, but not TDP-43 mitochondrial localisation, are likely associated with severity of CHCHD10-related diseases

    Genin EC, Bannwarth S, Lespinasse F, Ortega-Vila B, Fragaki K, Itoh K, Villa E, Lacas-Gervais S, Jokela M, Auranen M, Ylikallio E, Mauri-Crouzet A, Tyynismaa H, Vihola A, Augé G, Cochaud C, Sesaki H, Ricci JE, Udd B, Vives-Bauza C, Paquis-Flucklinger V.

    Neurobiol Dis. 2018 Nov;119:159-171.

    PMID: 30092269

  • MT-CYB deletion in an encephalomyopathy with hyperintensity of middle cerebellar peduncles

    Chaussenot A, Rouzier C, Fragaki K, Sacconi S, Ait-El-Mkadem S, Paquis-Flucklinger V, Bannwarth S.

    Neurol Genet. 2018 Oct; 4(5): e268.

    PMID: 30294674

  • Targeted next generation sequencing with an extended gene panel does not impact variant detection in mitochondrial diseases

    Plutino M, Chaussenot A, Rouzier C, Ait-El-Mkadem S, Fragaki K, Paquis-Flucklinger V, Bannwarth S.

    BMC Med Genet. 2018 Apr 7;19(1):57.

    PMID: 29625556

  • Use of circulating tumor cells in prospective clinical trials for  NSCLC patients - standardization of the pre-analytical conditions.

    Ilie M, Hofman V, Leroy S, Cohen C, Heeke S, Cattet F, Bence C, Lalvée S, Mouroux J, Marquette CH, Hofman P; STALKLUNG01 and AIR Study Consortium Investigators.

    Clin Chem Lab  Med. 2018 May 24;56(6):980-989.

    doi: 10.1515/cclm-2017-0764.

    PMID: 29397019.

  • Any Place for Immunohistochemistry  within the Predictive Biomarkers of Treatment in Lung Cancer Patients?

    Hofman V, Lassalle S, Bence C, Long-Mira E, Nahon-Estève S, Heeke S, Lespinet-Fabre V, Butori C, Ilié M, Hofman P.

    Cancers (Basel). 2018 Mar 13;10(3). pii: E70.

    doi: 10.3390/cancers10030070. Review.

    PMID: 29534030;

    PubMed Central PMCID: PMC5876645.

  • Using zebrafish PDX to screen drug sensitivity of endocrine-dependent cancers.

    Fior R, Ferreira MG.
    Proceedings of the National Academy of Sciences of the United States of America. 2018; 115(13):E2910.
    PMID: 29531074

  • Zbtb7a is a transducer for the control of promoter accessibility by NF-kappa B and multiple other transcription factors.


    Ramos Pittol JM, Oruba A, Mittler G, Saccani S*, van Essen D*.

    PLoS Biol. 2018 May 29;16(5):e2004526. doi: 10.1371/journal.pbio.2004526. eCollection 2018 May.

    (* equal contribution)

  • A metabolic interplay coordinated by HLX regulates myeloid differentiation and AML through partly overlapping pathways.


    Piragyte I, Clapes T, Polyzou A, Klein Geltink RI, Lefkopoulos S, Yin N, Cauchy P, Curtis JD, Klaeylé L, Langa X, Beckmann CCA, Wlodarski MW, Müller P, Van Essen D, Rambold A, Kapp FG, Mione M, Buescher JM, Pearce EL, Polyzos A, Trompouki E.

    Nat Commun. 2018 Aug 6;9(1):3090. doi: 10.1038/s41467-018-05311-4.

  • The hidden genomic and transcriptomic plasticity of giant marker chromosomes in cancer

    Macchia G, Severgnini M, Purgato S, Tolomeo D, Casciaro H, Cifola I, L’Abbate A, Loverro A, Palumbo O, Carella M, Bianchini L, Perini G, De Bellis G, Mertens F, Rocchi M, Storlazzi CT.

    Genetics, 2018, 208: 951-961.

    doi: 10.1534/genetics.117.300552

    PMID: 29279323

  • FoxM1 repression during human aging leads to mitotic decline and aneuploidy-driven full senescence.

    Macedo JC, Vaz S, Bakker B, Ribeiro R, Bakker PL, Escandell JM, Ferreira MG, Medema R, Foijer F, Logarinho E.

    Nature communications. 2018; 9(1):2834.

    PMID: 30026603
  • 18F-fluorodihydroxyphenylalanine PET/CT in pheochromocytoma and paraganglioma: relation to genotype and amino acid transport system L.

    Feral CC, Tissot FS, Tosello L, Fakhry N, Sebag F, Pacak K, Taïeb D.

    Eur J Nucl Med Mol Imaging. 2017 May;44(5):812-821

    PMID: 27900521
  • Clonal Heterogeneity Influences the Fate of New Adaptive Mutations

    Vázquez-García I@, Salinas F, Li J, Fischer A, Barré B, Hallin J, Bergström A, Alonso-Perez E, Warringer J, Mustonen V@, Liti G@.

    Cell Rep. 2017 ;21(3):732-744.

    PMID: 29045840

    @co-corresponding authors


  • A bipolar role of the transcription factor ERG for cnidarian germ layer formation and apical domain patterning

    Amiel RA*, Johnston H*, Chock T, Dahlin P, Iglesias M, Layden M, Röttinger E@ & Martindale MQ@

    Dev Biol. 2017 Oct 15;430(2):346-361

    PMID: 28818668

    * co-first, @ co-corresponding

  • Comprehensive study of three novel cases of TFEB-amplified renal cell carcinoma and review of the literature: evidence for a specific entity with poor outcome

    Mendel L, Ambrosetti D, Bodokh Y, Ngo-Mai M, Durand M, Simbsler-Michel C, Delhorbe M, Amiel J, Pedeutour F.

    Genes Chromosomes Cancer. 2017 Nov 11. 

    PMID: 29127730
  • Assembly defects of multiple respiratory chain complexes in a child with cardiac hypertrophy associated with a novel ACAD9 mutation

    Fragaki K, Chaussenot A, Boutron A, Bannwarth S, Rouzier C, Chabrol B, Paquis-Flucklinger V.

    Mol Genet Metab. 2017 Jul;121(3):224-226.

    PMID: 28529009

  • Structural and functional analysis of coral Hypoxia Inducible Factor

    Zoccola D, Morain J, Pagès G, Caminiti-Segonds N, Giuliano S, Tambutté S, Allemand D.

    PLoS One. 2017 Nov 8;12(11):e0186262.

    PMID: 29117182
  • Mutations in ACTRT1 and its enhancer RNA elements lead to aberrant activation of Hedgehog signaling in inherited and sporadic basal cell carcinomas

    Bal E, Park HS, Belaid-Choucair Z, Kayserili H, Naville M, Madrange M, Chiticariu E, Hadj-Rabia S, Cagnard N, Kuonen F, Bachmann D, Huber M, Le Gall C, Côté F, Hanein S, Rosti RÖ, Aslanger AD, Waisfisz Q, Bodemer C, Hermine O, Morice-Picard F, Labeille B, Caux F, Mazereeuw-Hautier J, Philip N, Levy N, Taieb A, Avril MF, Headon DJ, Gyapay G, Magnaldo T, Fraitag S, Crollius HR, Vabres P, Hohl D, Munnich A, Smahi A.

    Nat Med. 2017 Oct;23(10):1226-1233.

    PMID: 28869610
  • The differential spatiotemporal expression pattern of shelterin genes throughout lifespan

    Wagner K, Ying Y, Leong W, Jiang J, Hu X, Chen Y, Michiels JF, Lu Y, Gilson E*, Wagner N, Ye J

    Aging (Albany NY). 2017 Apr;9(4):1219-1232. doi: 10.18632/aging.101223

    PMID: 28437249


  • Single-cell functional and chemosensitive profiling of combinatorial colorectal therapy in zebrafish xenografts.

    Fior R, Póvoa V, Mendes RV, Carvalho T, Gomes A, Figueiredo N, Ferreira MG.

    Proceedings of the National Academy of Sciences of the United States of America. 2017; 114(39):E8234-E8243.

    PMID: 28835536
  • Human Retrotransposons in Health and Disease

    Cristofari, Gael (Ed.)

    Springer, 2017. Book.

    ISBN 978-3-319-48344-3

  • Cancer suppression by systemic inactivation of p38MAPK

    Brichkina A, Bulavin DV.

    Oncotarget. 2017 Feb 28;8(9):14275-14276

    PMID: 28199960

  • Rapid decay  of engulfed extracellular miRNA by XRN1 exonuclease promotes transient epithelial-mesenchymal transition.

    Zangari J, Ilie M, Rouaud F, Signetti L, Ohanna M, Didier R, Roméo B, Goldoni D, Nottet N, Staedel C, Gal J, Mari B, Mograbi B, Hofman P, Brest P.

    Nucleic Acids Res. 2017 Apr 20;45(7):4131-4141.

    doi: 10.1093/nar/gkw1284.

    PMID: 27994032;

    Pubmed Central PMCID: PMC5397191.

  • Quality Matters: 2016 Annual Conference of the National Infrastructures for Biobanking.

    Doucet M, Becker KF, Björkman J, Bonnet J, Clément B, Daidone MG, Duyckaerts  C, Erb G, Haslacher H, Hofman P, Huppertz B, Junot C, Lundeberg J, Metspalu A, Lavitrano M, Litton JE, Moore HM, Morente M, Naimi BY, Oelmueller U, Ollier B, Parodi B, Ruan L, Stanta G, Turano P, Vaught J, Watson P, Wichmann HE, Yuille M,  Zaomi M, Zatloukal K, Dagher G.

    Biopreserv Biobank. 2017 Jun;15(3):270-276.

    doi: 10.1089/bio.2016.0053. Epub 2016 Dec 19.

    PMID: 27992240;

    Pubmed Central PMCID: PMC5586151.

  • Liquid biopsy for early detection of lung cancer.

    Hofman P.

    Curr Opin Oncol.  2017 Jan;29(1):73-78. Review.

    PMID: 27906860.

  • Reproducibility of PD-L1 assessment in non-small cell lung  cancer-know your limits but never stop trying to exceed them.

    Ilie M, Hofman P.

    Transl Lung Cancer  Res. 2017 Dec;6(Suppl 1):S51-S54.

    doi: 10.21037/tlcr.2017.10.13.

    PMID: 29299411;

    PubMed Central PMCID: PMC5750161.

  • Meningeal SWI/SNF related, matrix-associated, actin-dependent regulator of chromatin, subfamily B member 1 (SMARCB1)-deficient tumours: an emerging group of meningeal tumours.

    Dadone B, Fontaine D, Mondot L, Cristofari G, Jouvet A, Godfraind C, Varlet P, Ranchère-Vince D, Coindre JM, Gastaud L, Baudoin C, Peyron AC, Thyss A, Coutts M, Michiels JF, Pedeutour F, Burel-Vandenbos F; RENOP.

    Neuropathol Appl Neurobiol. 2017 Aug;43(5):433-449.

    PMID: 27732747
  • Monogenic diabetes syndromes: Locus-specific databases for Alström, Wolfram, and Thiamine-responsive megaloblastic anemia

    Astuti D, Sabir A, Fulton P, Zatyka M, Williams D, Hardy C, Milan G, Favaretto F, Yu-Wai-Man P, Rohayem J, López de Heredia M, Hershey T, Tranebjaerg L, Chen JH, Chaussenot A, Nunes V, Marshall B, McAfferty S, Tillmann V, Maffei P, Paquis-Flucklinger V, Geberhiwot T, Mlynarski W, Parkinson K, Picard V, Bueno GE, Dias R, Arnold A, Richens C, Paisey R, Urano F, Semple R, Sinnott R, Barrett TG.

    Hum Mutat. 2017 Jul;38(7):764-777.

    PMID: 28432734


  • Peritoneal carcinomatosis of colorectal cancer: novel clinical and molecular outcomes.

    Massalou D, Benizri E, Chevallier A, Duranton-Tanneur V, Pedeutour F, Benchimol D, Béréder JM.

    Am J Surg. 2017 Feb;213(2):377-387. doi: 10.1016/j.amjsurg.2016.03.008. Epub 2016 Aug 5.

    PMID: 27816197
  • Conspicuous morphological differentiation without speciation in Anemonia viridis (Cnidaria, Actiniaria)

    Mallien C, Porro B, Zamoum T, Olivier C, Wiedenmann J, Furla P & Forcioli D. 

    Systematics and Biodiversity. 16 (3), Issue 3, 271-386. 

  • SIRT6 interacts with TRF2 and promotes its degradation in response to DNA damage

    Rizzo A, Iachettini S, Salvati E, Zizza P, Maresca C, D’Angelo C, Benarroch-Popivker D, Capolupo A, Del Gaudio F, Cosconati S, Di Maro S, Merlino F, Novellino E, Amoreo CA, Mottolese M, Sperduti I, Gilson E, Biroccio A.

    Nucleic Acids Res. 2017 Feb 28 ;45(4) :1820-1834

    PMID: 27923994


  • Test anxiety and telomere length: Academic stress in adolescents may not cause rapid telomere erosion

    Test anxiety and telomere length: Academic stress in adolescents may not cause rapid telomere erosion.

    Oncotarget. 2017 Feb 14;8(7):10836-10844

    PMID: 28122333

  • Dynamics under the Telomeric Bridge

    Pisano S, Gilson E, Giraud-Panis MJ.

    Mol Cell. 2017 Nov 16;68(4):643-644

    PMID: 29149592

  • A novel CISD2 mutation associated with a classical Wolfram syndrome phenotype alters Ca2+ homeostasis and ER-mitochondria interactions

    Rouzier C, Moore D, Delorme C, Lacas-Gervais S, Ait-El-Mkadem S, Fragaki K, Burté F, Serre V, Bannwarth S, Chaussenot A, Catala M, Yu-Wai-Man P, Paquis-Flucklinger V.

    Hum Mol Genet. 2017 May 1;26(9):1599-1611.

    PMID: 28335035

  • Mutations in MDH2, Encoding a Krebs Cycle Enzyme, Cause Early-Onset Severe Encephalopathy

    Ait-El-Mkadem S, Dayem-Quere M, Gusic M, Chaussenot A, Bannwarth S, François B, Genin EC, Fragaki K, Volker-Touw CLM, Vasnier C, Serre V, van Gassen KLI, Lespinasse F, Richter S, Eisenhofer G, Rouzier C, Mochel F, De Saint-Martin A, Abi Warde MT, de Sain-van der Velde MGM, Jans JJM, Amiel J, Avsec Z, Mertes C, Haack TB, Strom T, Meitinger T, Bonnen PE, Taylor RW, Gagneur J, van Hasselt PM, Rötig A, Delahodde A, Prokisch H, Fuchs SA, Paquis-Flucklinger V.

    Am J Hum Genet. 2017 Jan 5;100(1):151-159.

    PMID: 27989324

  • Membrane-bound ICAM-1 contributes to the onset of proinvasive tumor stroma by controlling acto-myosin contractility in carcinoma-associated fibroblasts.

    Bonan S, Albrengues J, Grasset E, Kuzet SE, Nottet N, Bourget I, Bertero T, Mari B, Meneguzzi G, Gaggioli C.

    Oncotarget. 2017 Jan 3;8(1):1304-1320.

    PMID: 27901489

  • Adequately defining tumor cell proportion in tissue samples for molecular testing improves interobserver reproducibility of its assessment.

    Lhermitte B, Egele C, Weingertner N, Ambrosetti D, Dadone B, Kubiniek V, Burel-Vandenbos F, Coyne J, Michiels JF, Chenard MP, Rouleau E, Sabourin JC, Bellocq JP.

    Virchows Arch. 2017 Jan;470(1):21-27. doi: 10.1007/s00428-016-2042-6. Epub 2016 Nov 16.

    PMID: 27853865
  • MET immunolabelling is a useful predictive tool for MET gene amplification in glioblastoma.

    Burel-Vandenbos F, Ngo-Mai M, Dadone B, Di Mauro I, Gimet S, Saada-Bouzid E, Bourg V, Almairac F, Fontaine D, Virolle T, Pedeutour F.

    Neuropathol Appl Neurobiol. 2017 Apr;43(3):252-266. doi: 10.1111/nan.12320. Epub 2016 Apr 4.

    PMID: 26946354
  • Association of Oncogenic Mutations in Patients With Advanced Cutaneous Squamous Cell Carcinomas Treated With Cetuximab.

    Picard A, Pedeutour F, Peyrade F, Saudes L, Duranton-Tanneur V, Chamorey E, Cardot-Leccia N, Sudaka A, Ettaiche M, Benchetrit M, Poissonnet G, Weinbreck N, Dadone B, Lacour JP, Passeron T, Montaudié H.

    JAMA Dermatol. 2017 Apr 1;153(4):291-298. doi: 10.1001/jamadermatol.2017.0270.

    PMID: 28259104
  • PDGFRa amplification in multiple skin lesions of undifferentiated pleomorphic sarcoma: A clue for intimal sarcoma metastases.

    Osio A, Vignon-Pennamen MD, Pedeutour F, Le Maignan C, Koskas F, Lebbé C, Janin A, Battistella M.

    J Cutan Pathol. 2017 May;44(5):477-479. doi: 10.1111/cup.12907. Epub 2017 Feb 15.

    PMID: 28105789
  • Congenital Infantile Fibrosarcoma Associated With a Lipofibromatosis-Like Component: One Train May Be Hiding Another.

    Swiadkiewicz R, Galmiche L, Belhous K, Boccara O, Fraitag S, Pedeutour F, Dadone B, Buis J, Picard A, Orbach D, Kadlub N.

    Am J Dermatopathol. 2017 Jun;39(6):463-467. doi: 10.1097/DAD.0000000000000696.

    PMID: 28525423
  • Detection of RAS genes mutation using the Cobas(®) method in a private laboratory of pathology: Medical and economical study in comparison to a public platform of molecular biology of cancer

    Albertini AF, Raoux D, Neumann F, Rossat S, Tabet F, Pedeutour F, Duranton-Tanneur V, Kubiniek V, Vire O, Weinbreck N.

    Bull Cancer. 2017 Jul - Aug;104(7-8):662-674. doi: 10.1016/j.bulcan.2017.05.005. Epub 2017 Jul 5. French.

    PMID: 28688743
  • Severe defect in mitochondrial complex I assembly with mitochondrial DNA deletions in ACAD9-deficient mild myopathy

    Fragaki K, Chaussenot A, Boutron A, Bannwarth S, Cochaud C, Richelme C, Sacconi S, Paquis-Flucklinger V.

    Muscle Nerve. 2017 Jun;55(6):919-922. 

    PMID: 27438479
  • Atezolizumab in advanced non-small cell lung cancer.

    Ilie M, Hofman P.

    J Thorac Dis. 2017 Oct;9(10):3603-3606.

    doi: 10.21037/jtd.2017.09.73.

    PMID: 29268352;

    PubMed Central PMCID: PMC5723868.

  • Circulating tumour cells as a potential screening tool for lung cancer (the AIR study): protocol of a prospective multicentre cohort study in France.

    Leroy S, Benzaquen J, Mazzetta A, Marchand-Adam S, Padovani B, Israel-Biet D, Pison C, Chanez P, Cadranel J, Mazières J, Jounieaux V, Cohen C, Hofman V, Ilie M, Hofman P, Marquette CH; AIR Project Study Group.

    BMJ Open. 2017 Dec 26;7(12):e018884.

    doi: 10.1136/bmjopen-2017-018884.

    PMID: 29282271;

    PubMed Central PMCID: PMC5770962.

  • Integration site selection by retroviruses and transposable elements in eukaryotes.

    Sultana T*, Zamborlini A*, Cristofari G@, Lesage P@

    Nat Rev Genet. 2017 May;18(5):292-308.

    PMID: 28286338

    *co-first authors, @co-last authors

  • Optimization of EGFR mutation detection by the fully-automated qPCR-based Idylla system on tumor tissue from patients with non-small cell lung cancer.

    Ilie M, Butori C, Lassalle S, Heeke S, Piton N, Sabourin JC, Tanga V, Washetine K, Long-Mira E, Maitre P, Yazbeck N, Bordone O, Lespinet V, Leroy S, Cohen C, Mouroux J, Marquette CH, Hofman V, Hofman P.

    Oncotarget. 2017 Oct 4;8(61):103055-103062.

    doi: 10.18632/oncotarget.21476. eCollection 2017 Nov 28.

    PMID: 29262544;

    PubMed Central PMCID: PMC5732710.

  • [PD1/PD-L1 immunohistochemistry in thoracic oncology: Where are we?].

    Hofman P, Ilié M, Lassalle S, Long E, Bence C, Butori C, Hofman V.

    Ann Pathol. 2017 Feb;37(1):39-45.

    doi: 10.1016/j.annpat.2016.12.006. Epub 2017 Jan 31. French. Erratum in: Ann Pathol. 2017 Aug;37(4):344.

    PMID: 28159404.

  • MAPK signaling is necessary for neurogenesis in Nematostella vectensis

    Layden MJ, Johnston H, Amiel AR, Havrilak J, Steinworth B, Chock T, Röttinger E, Martindale MQ.

    BMC Biol. 2016 Aug 1;14:61.

    PMID: 27480076

  • Immunotherapy supplanting chemotherapy for upfront treatment of advanced non-small cell lung cancer: what's next?

    Ilie M, Hofman P.

    J Thorac Dis. 2017 May;9(5):E519-E521.

    doi: 10.21037/jtd.2017.03.155.

    PMID: 28616326;

    PubMed  Central PMCID: PMC5465171.

  • NGS analysis on tumor tissue and cfDNA for genotype-directed therapy in metastatic NSCLC patients. Between hope and hype?

    Falk AT, Heeke S, Hofman V, Lespinet V, Ribeyre C, Bordone O, Poudenx M, Otto J, Garnier G, Castelnau O, Guigay J, Leroy S, Marquette CH, Hofman P, Ilié M.

    Expert Rev Anticancer Ther. 2017 Aug;17(8):681-685.

    doi: 10.1080/14737140.2017.1331736. Epub 2017 May 22.

    PMID: 28511612.

  • Composite biomarkers defined by multiparametric immunofluorescence analysis identify ALK-positive adenocarcinoma as a potential target for immunotherapy.

    Roussel H, De Guillebon E, Biard L, Mandavit M, Gibault L, Fabre E, Antoine M, Hofman P, Beau-Faller M, Blons H, Danel C, Barthes FLP, Gey A, Granier C, Wislez M, Laurent-Puig P, Oudard S, Bruneval P, Badoual C, Cadranel J, Tartour E.

    Oncoimmunology. 2017 Feb 21;6(4):e1286437.

    doi: 10.1080/2162402X.2017.1286437. eCollection 2017.

    PMID: 28507793;

    PubMed Central PMCID: PMC5414864.

  • Inverted conjunctival papilloma: a certainly underestimated high-risk lesion for carcinomatous transformation-a case report.

    Lassalle S, Maschi C, Caujolle JP, Giordanengo V, Hofman P.

    Can J Ophthalmol. 2017 Feb;52(1):e30-e31.

    doi: 10.1016/j.jcjo.2016.08.003. Epub 2016 Nov 16.

    PMID: 28237169.


  • Expression of MET in circulating tumor cells correlates with expression in tumor tissue from advanced-stage lung cancer patients.

    Ilie M, Szafer-Glusman E, Hofman V, Long-Mira E, Suttmann R, Darbonne W, Butori C, Lalvée S, Fayada J, Selva E, Yu W, Marquette CH, Shames DS, Punnoose E, Hofman P.

    Oncotarget. 2017 Apr 18;8(16):26112-26121.

    doi: 10.18632/oncotarget.15345.

    PMID: 28212540;

    Pubmed Central PMCID: PMC5432243.

  • Pathology of infectious diseases: what does the future hold?

    Hofman P, Lucas S, Jouvion G, Tauziède-Espariat A, Chrétien F, Cathomas G.

    Virchows Arch. 2017  May;470(5):483-492.

    doi: 10.1007/s00428-017-2082-6. Epub 2017 Feb 10. Review.

    PMID: 28188440.

  • Contrasting evolutionary genome dynamics between domesticated and wild yeasts

    Yue JX, Li J, Aigrain L, Hallin J, Persson K, Oliver K, Bergström A, Coupland P, Warringer J, Lagomarsino MC, Fischer G, Durbin R, Liti G.

    Nat Genet. 2017 Jun;49(6):913-924. doi: 10.1038/ng.3847. Epub 2017 Apr 17.

    PMID: 28416820

  • Liquid biopsy in lung cancer.

    Mlika M, Hofman P, Dziri C, Mezni F.

    Tunis Med. 2017 Novembre;95(11):965-971.

    Pubmed PMID:

  • RECIST response and variation of circulating tumour cells in phase 1 trials: A prospective multicentric study.

    Massard C, Borget I, Farace F, Aspeslagh S, Le Deley MC, Le Tourneau C, Bidard FC, Pierga JY, Dieras V, Hofman P, Spano JP, Ferte C, Lacroix L, Soria JC.

    Eur J Cancer. 2017 Sep;83:185-193.

    doi: 10.1016/j.ejca.2017.05.016. Epub 2017 Jul 22.

    PMID: 28743036.

  • de novo assembly and population genomic survey of natural yeast isolates with the Oxford Nanopore MinION sequencer

    Istace B, Friedrich A, d'Agata L, Faye S, Payen E, Beluche O, Caradec C, Davidas S, Cruaud C, Liti G, Lemainque A, Engelen S, Wincker P, Schacherer J, Aury JM.

    Gigascience. 2017 Feb 1;6(2):1-13. doi: 10.1093/gigascience/giw018.
    PMID: 28369459

  • Stem Cell-Like Properties of CK2β-down Regulated Mammary Cells.

    Duchemin-Pelletier E, Baulard M, Spreux E, Prioux M, Burute M, Mograbi B, Guyon L, Théry M, Cochet C, Filhol O. 

    Cancers (Basel). 2017 Aug 31;9(9). pii: E114. doi: 10.3390/cancers9090114.

    PubMed PMID: 28858215

  • Identification of Nitrogen Consumption Genetic Variants in Yeast Through QTL Mapping and Bulk Segregant RNA-Seq Analyses

    Cubillos FA, Brice C, Molinet J, Tisné S, Abarca V, Tapia SM, Oporto C, García V, Liti G, Martínez C.

    G3 (Bethesda). 2017 Jun 7;7(6):1693-1705. doi: 10.1534/g3.117.042127.

    PMID: 28592651

  • The genetic architecture of low-temperature adaptation in the wine yeast Saccharomyces cerevisiae

    García-Ríos E, Morard M, Parts L, Liti G, Guillamón JM.

    BMC Genomics. 2017 Feb 14;18(1):159. doi: 10.1186/s12864-017-3572-2.

    PMID: 28196526

  • Mismatch Repair Incompatibilities in Diverse Yeast Populations

    Bui DT, Friedrich A, Al-Sweel N, Liti G, Schacherer J, Aquadro CF, Alani E.

    Genetics. 2017 Apr;205(4):1459-1471. doi: 10.1534/genetics.116.199513. Epub 2017 Feb 13.

    PMID: 28193730

  • Role for the ATPase inhibitory factor 1 in the environmental carcinogen-induced Warburg phenotype.

    Hardonnière K, Fernier M, Gallais I, Mograbi B, Podechard N, Le Ferrec E, Grova N, Appenzeller B, Burel A, Chevanne M, Sergent O, Huc L, Bortoli S, Lagadic-Gossmann D. 

    Sci Rep. 2017 Mar 15;7(1):195. doi:10.1038/s41598-017-00269-7.

    PMID: 28298645;

    PubMed Central PMCID: PMC5428028

  • Targeting eIF5A Hypusination Prevents Anoxic Cell Death through Mitochondrial Silencing and Improves Kidney Transplant Outcome.

    Melis N, Rubera I, Cougnon M, Giraud S, Mograbi B, Belaid A, Pisani DF, Huber SM, Lacas-Gervais S, Fragaki K, Blondeau N, Vigne P, Frelin C, Hauet T, Duranton C, Tauc M.

    J Am Soc Nephrol. 2017 Mar;28(3):811-822. doi: 10.1681/ASN.2016010012. Epub 2016 Sep 9.

    PMID: 27612998;

    PubMed Central PMCID: PMC5328152.


  • Immunotherapy in Non-Small Cell Lung Cancer: Biological Principles and Future Opportunities.

    Ilie M, Benzaquen J, Hofman V, Lassalle S, Yazbeck N, Leroy S, Heeke S, Bence C, Mograbi B, Glaichenhaus N, Marquette CH, Hofman P.

    Curr Mol Med. 2017;17(8):527-540. doi: 10.2174/1566524018666180222114038.

    PubMed PMID: 29473504.

  • Diversity of Cnidarian Muscles: Function, Anatomy, Development and Regeneration

    Leclère L, Röttinger E.

    Front Cell Dev Biol. 2017 Jan 23;4:157.

    PMID: 28168188

  • Liquid Biopsy and Therapeutic Targets: Present and Future Issues in Thoracic Oncology.

    Hofman P.

    Cancers (Basel). 2017 Nov 10;9(11). pii: E154.

    doi: 10.3390/cancers9110154. Review.

    PMID: 29125548;

    PubMed Central PMCID: PMC5704172.

  • Erratum à l’article : « Immunohistochimie PD-1/PD-L1 en oncologie thoracique : où en sommes-nous ? »

    Hofman P, Ilié M, Lassalle S, Long É, Coraline Bence, Butori C, Hofman V.

    [Ann. Pathol. 37(1) (2017) 39–45]. Ann Pathol. 2017 Aug;37(4):344.

    doi: 10.1016/j.annpat.2017.06.002. Epub 2017 Aug 1. French.

    PMID: 28778623.

  • Use of the 22C3 anti-PD-L1 antibody to determine PD-L1 expression in multiple  automated immunohistochemistry platforms.

    Ilie M, Khambata-Ford S, Copie-Bergman C, Huang L, Juco J, Hofman V, Hofman P.

    PLoS One. 2017 Aug 10;12(8):e0183023.

    doi: 10.1371/journal.pone.0183023. eCollection 2017.

    Erratum in: PLoS One. 2017 Oct 13;12 (10 ):e0186537.

    PMID: 28797130;

    PubMed Central PMCID: PMC5552229.

  • The liquid biopsy: a tool for a combined diagnostic and theranostic approach for care of a patient with late-stage lung carcinoma presenting with bilateral ocular metastases.

    Bouhlel L, Hofman V, Maschi C, Ilié M, Allégra M, Marquette CH, Audigier-Valette C, Thariat J, Hofman P.

    Expert Rev Anticancer Ther. 2017 Dec;17(12):1087-1092.

    doi: 10.1080/14737140.2017.1398089. Epub 2017 Nov 2.

    PMID: 29069959.

  • PD-L1 immunohistochemistry for non-small cell lung carcinoma: which strategy should be adopted?

    Hofman P.

    Expert Rev Mol Diagn. 2017 Dec;17(12):1097-1108.

    doi: 10.1080/14737159.2017.1398083. Epub 2017 Nov 1. Review.

    PMID: 29069958.

  • Correction: Use of the 22C3 anti-PD-L1 antibody to determine PD-L1 expression  in multiple automated immunohistochemistry platforms.

    Ilie M, Khambata-Ford S, Copie-Bergman C, Huang L, Juco J, Hofman V, Hofman P.

    PLoS One. 2017 Oct 13;12(10):e0186537.

    doi: 10.1371/journal.pone.0186537. eCollection 2017.

    PMID: 29028832;

    PubMed Central PMCID: PMC5640228.

  • Response to first line  chemotherapy regimen is associated with efficacy of nivolumab in non-small-cell lung cancer.

    Kaderbhai CG, Richard C, Fumet JD, Aarnink A, Ortiz-Cuaran S, Pérol M, Foucher P, Coudert B, Favier L, Lagrange A, Limagne E, Boidot R, Ladoire S, Poudenx M, Ilie M, Hofman P, Saintigny P, Ghiringhelli F.

    Oncoimmunology. 2017 Jun 16;6(9):e1339856.

    doi: 10.1080/2162402X.2017.1339856. eCollection 2017.

    PMID: 28932641;

    PubMed Central PMCID: PMC5599088.

  • Training the Next Generation of Biobankers: A Two-Year Master's Course in the Management of Biobanks.

    Gormally E, Hardy I, Caboux E, di Donato JH, Hainaut P, Hofman P.

    Biopreserv Biobank. 2017 Oct;15(5):438-450.

    doi: 10.1089/bio.2017.0002. Epub 2017 Sep 18.

    PMID: 28922617.

  • ALK in Non-Small Cell Lung Cancer (NSCLC) Pathobiology, Epidemiology, Detection from Tumor Tissue and Algorithm Diagnosis in a Daily Practice.

    Hofman P.

    Cancers (Basel). 2017 Aug 12;9(8). pii: E107.

    doi: 10.3390/cancers9080107. Review.

    PMID: 28805682;

    PubMed Central PMCID: PMC5575610.

  • ALK Status Assessment with Liquid Biopsies of Lung Cancer Patients.

    Hofman P.

    Cancers (Basel). 2017 Aug 12;9(8). pii: E106.

    doi: 10.3390/cancers9080106. Review.

    PMID: 28805673;

    PubMed Central PMCID: PMC5575609.

  • MiR-223-3p inhibits angiogenesis and promotes resistance to cetuximab in head and neck squamous cell carcinoma.

    Bozec A, Zangari J, Butori-Pepino M, Ilie M, Lalvee S, Juhel T, Butori C, Brest P, Hofman P, Vouret-Craviari V.

    Oncotarget. 2017 Jul 11;8(34):57174-57186.

    doi: 10.18632/oncotarget.19170. eCollection 2017 Aug 22.

    PMID: 28915663;

    PubMed Central PMCID: PMC5593634.

  • A novel technique to combine and analyse spatial and temporal expression datasets: A case study with the sea anemone Nematostella vectensis to identify potential gene interactions

    Abdol AM, Röttinger E, Jansson F, Kaandorp JA.

    Dev Biol. 2017 Jun 8. pii: S0012-1606(17)30100-8.

    PMID: 28602952

  • TRF2-Mediated Control of Telomere DNA Topology as a Mechanism for Chromosome-End Protection.

    Benarroch-Popivker D, Pisano S, Mendez-Bermudez A, Lototska L, Kaur P, Bauwens S, Djerbi N, Latrick CM, Fraisier V, Pei B, Gay A, Jaune E, Foucher K, Cherfils-Vicini J, Aeby E, Miron S, Londoño-Vallejo A, Ye J, Le Du MH, Wang H, Gilson E,* Giraud-Panis MJ.

    Mol Cell. 2016 Jan 21;61(2):274-86

    PMID: 26774283


  • Defective DNA single-strand break repair is responsible for senescence and neoplastic escape of epithelial cells

    Nassour J, Martien S, Martin N, Deruy E, Tomellini E, Malaquin N, Bouali F, Sabatier L, Wernert N, Pinte S, Gilson E, Pourtier A, Pluquet O, Abbadie C.

    Nat C ommun., 2016, Jan 29;7:10399

    PMID: 26822533


  • Western diet induces a shift in microbiota composition enhancing susceptibility to Adherent-Invasive E. coli infection and intestinal inflammation.

    Agus A, Denizot J, Thévenot J, Martinez-Medina M, Massier S, Sauvanet P, Bernalier-Donadille A, Denis S, Hofman P, Bonnet R, Billard E, Barnich N.

    Sci Rep. 2016 Jan 8;6:19032.

    doi: 10.1038/srep19032.

    PMID: 26742586;

    Pubmed Central PMCID: PMC4705701.

  • Three Rounds of External Quality Assessment in France to Evaluate the Performance of 28 Platforms for Multiparametric Molecular Testing in Metastatic Colorectal and Non-Small Cell Lung Cancer.

    Dequeker EM, Keppens C, Egele C, Delen S, Lamy A, Lemoine A, Sabourin JC, Andrieu C, Ligtenberg M, Fetique D, Tops B, Descarpentries C, Blons H, Denoux Y,  Aube C, Penault-Llorca F, Hofman P, Leroy K, Le Marechal C, Doucet L, Duranton-Tanneur V, Pedeutour F, Soubeyran I, Côté JF, Emile JF, Vignaud JM, Monhoven N, Haddad V, Laurent-Puig P, van Krieken H, Nowak F, Lonchamp E, Bellocq JP, Rouleau E.

    J Mol Diagn. 2016 Mar;18(2):205-14.

    doi: 10.1016/j.jmoldx.2015.09.004. Epub 2016 Jan 2.

    PMID: 26752307.

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

    Klionsky DJ, … E, Belaid A, …, Brest P, …,  Hofman P, …, Mograbi B, …, Vouret-Craviari V, et al.

    Autophagy. 2016;12(1):1-222.

    doi: 10.1080/15548627.2015.1100356. Erratum in: Autophagy. 2016;12(2):443. Selliez, Iban [corrected to Seiliez, Iban].

    PMID: 26799652;

    Pubmed Central PMCID: PMC4835977.

  • Assessment of the PD-L1 status by immunohistochemistry: challenges and perspectives for therapeutic strategies in lung cancer patients.

    Ilie M, Hofman V, Dietel M, Soria JC, Hofman P.

    Virchows Arch. 2016 May;468(5):511-25.

    doi: 10.1007/s00428-016-1910-4. Epub 2016 Feb 25. Review.

    PMID: 26915032.

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Dmitry Bulavin
    Autophagy, 2016, Jan2;12(1):1-222

  • A higher-order entity formed by the flexible assembly of RAP1 with TRF2.

     Gaullier G, Miron S, Pisano S, Buisson R, Le Bihan YV, Tellier-Lebègue C, Messaoud W, Roblin P, Guimarães BG, Thai R, Giraud-Panis MJ, Gilson E, Le Du MH.

    Nucleic Acids Res., 2016, Jan 8.pii:gkv1531

    PMID: 26748096


  • Powerful decomposition of complex traits in a diploid model

    Hallin J, Märtens K, Young AI, Zackrisson M, Salinas F, Parts L, Warringer J, Liti G.

    Nat Commun. 2016 Nov 2;7:13311. doi: 10.1038/ncomms13311.

    PMID: 27804950

  • ISSY32 Highlights

    Liti G, Buzzini P.

    Yeast. 2016 Jul;33(7):241-2. doi: 10.1002/yea.3176.

    PMID: 27383392

  • Differential senescence capacities in meibomian gland carcinoma and basal cell carcinoma.

    Zhang L, Huang X, Zhu X, Ge S, Gilson E, Jia R, Ye J, Fan X.

    Int J Cancer., 2016, Mar15 ;138(6) :144252

    PMID: 26437300

  • Ploidy influences the functional attributes of de novo lager yeast hybrids

    Krogerus K, Arvas M, De Chiara M, Magalhães F, Mattinen L, Oja M, Vidgren V, Yue JX, Liti G, Gibson B.

    Appl Microbiol Biotechnol. 2016 Aug;100(16):7203-22. doi: 10.1007/s00253-016-7588-3.

    PMID: 27183995

  • The environmental carcinogen benzo[a]pyrene induces a Warburg-like metabolic reprogramming dependent on NHE1 and associated with cell survival.

    Hardonnière K, Saunier E, Lemarié A, Fernier M, Gallais I, Héliès-Toussaint C, Mograbi B, Antonio S, Bénit P, Rustin P, Janin M, Habarou F, Ottolenghi C, Lavault MT, Benelli C, Sergent O, Huc L, Bortoli S, Lagadic-Gossmann D.

    Sci Rep. 2016 Aug 4; 6:30776. doi: 10.1038/srep30776.

    PMID: 27488617; PubMed Central PMCID: PMC4973274.

  • Predicting quantitative traits from genome and phenome with near perfect accuracy

    Märtens K, Hallin J, Warringer J, Liti G, Parts L.

    Nat Commun. 2016 May 10;7:11512. doi: 10.1038/ncomms11512.

    PMID: 27160605

  • Detection and characterization of circulating  tumor cells in lung cancer: Why and how?

    Hofman VJ, Ilie M, Hofman PM.

    Cancer Cytopathol. 2016 Jun;124(6):380-7.

    doi: 10.1002/cncy.21651. Epub 2015 Nov 20.

    PMID: 26587794.

  • Nitric Oxide Synthase 2 Improves Proliferation and Glycolysis of Peripheral γδ T Cells

    Douguet L, Cherfils-Vicini J, Bod L, Lengagne R, Gilson E, Prévost-Blondel A.

    PLoS One. 2016 Nov 3;11(11):e0165639. doi: 10.1371/journal.pone.0165639. eCollection 2016

    PMID: 27812136


  • Challenging a dogma: co-mutations exist in MAPK pathway genes in colorectal cancer.

    Grellety T, Gros A, Pedeutour F, Merlio JP, Duranton-Tanneur V, Italiano A, Soubeyran I.

    Virchows Arch. 2016 Oct;469(4):459-64. doi: 10.1007/s00428-016-1991-0. Epub 2016 Jul 11.

    PMID: 27401719
  • Vascular stiffness mechanoactivates YAP/TAZ-dependent glutaminolysis to drive pulmonary hypertension.

    Bertero T, Oldham WM, Cottrill KA, Pisano S, Vanderpool RR, Yu Q, Zhao J, Tai Y, Tang Y, Zhang YY, Rehman S, Sugahara M, Qi Z, Gorcsan J 3rd, Vargas SO, Saggar R, Saggar R, Wallace WD, Ross DJ, Haley KJ, Waxman AB, Parikh VN, De Marco T, Hsue PY, Morris A, Simon MA, Norris KA, Gaggioli C, Loscalzo J, Fessel J, Chan SY.

    J Clin Invest. 2016 Sep 1;126(9):3313-35.

    PMID: 27548520
  • Autophagy : Moving Benchside Promises to Patient Bedsides

    Belaid A, Ndiaye PD, Filippakis H, Roux J, Röttinger E, Graba Y, Brest P, Hofman P, Mograbi B.

    Curr Cancer Drug Targets. 2015;15(8):684-702.

    PMID: 26452384

  • A new mutation in the mitochondrial tRNAPro gene associated with early-onset neuromuscular phenotype and ragged-red fibers

    Morel G, Bannwarth S, Chaussenot A, Cano A, Fragaki K, Ait-El-Mkadem S, Rouzier C, De Paula AM, Chabrol B, Paquis-Flucklinger V.

    Neuromuscul Disord. 2016 Dec;26(12):885-889

    PMID: 27816331

  • Inactivation of Pif1 helicase causes a mitochondrial myopathy in mice

    Bannwarth S, Berg-Alonso L, Augé G, Fragaki K, Kolesar JE, Lespinasse F, Lacas-Gervais S, Burel-Vandenbos F, Villa E, Belmonte F, Michiels JF, Ricci JE, Gherardi R, Harrington L, Kaufman BA, Paquis-Flucklinger V.

    Mitochondrion. 2016 Sep;30:126-37. 

    PMID: 26923168 

  • Yeast 2.0: a new chapter

    Liti G.

    Yeast. 2016 Jan;33(1):3-4. doi: 10.1002/yea.3143.

    PMID: 26756884


  • Coenzyme Q10 defects may be associated with a deficiency of Q10-independent mitochondrial respiratory chain complexes

    Fragaki K, Chaussenot A, Benoist JF, Ait-El-Mkadem S, Bannwarth S, Rouzier C, Cochaud C, Paquis-Flucklinger V.

    Biol Res. 2016 Jan 8;49:4

    PMID: 26742794 

  • CHCHD10 mutations promote loss of mitochondrial cristae junctions with impaired mitochondrial genome maintenance and inhibition of apoptosis

    Genin EC, Plutino M, Bannwarth S, Villa E, Cisneros-Barroso E, Roy M, Ortega-Vila B, Fragaki K, Lespinasse F, Pinero-Martos E, Augé G, Moore D, Burté F, Lacas-Gervais S, Kageyama Y, Itoh K, Yu-Wai-Man P, Sesaki H, Ricci JE, Vives-Bauza C, Paquis-Flucklinger V.

    EMBO Mol Med. 2016 Jan 1;8(1):58-72.

    PMID: 26666268 

  • Fibroblast activation in cancer: when seed fertilizes soil.

    Kuzet SE, Gaggioli C.

    Cell Tissue Res. 2016 Sep;365(3):607-19. doi: 10.1007/s00441-016-2467-x.

    PMID: 27474009

  • ERK1/2/MAPK pathway-dependent regulation of the telomeric factor TRF2

    Picco V, Coste I, Giraud-Panis MJ, Renno T, Gilson E, Pagès G.

    Oncotarget. 2016 Jul 19;7(29):46615-46627. doi: 10.18632/oncotarget.10316

    PMID: 27366950


  • The rise of the starlet sea anemone Nematostella vectensis as a model system to investigate development and regeneration

    Layden MJ, Rentzsch F, Röttinger E.

    Wiley Interdiscip Rev Dev Biol. 2016 Jul;5(4):408-28.

    PMID: 26894563

  • p38MAPK builds a hyaluronan cancer niche to drive lung tumorigenesis.

    Brichkina A, Bertero T, Loh HM, Nguyen NT, Emelyanov A, Rigade S, Ilie M, Hofman P, Gaggioli C, Bulavin DV.

    Genes Dev. 2016 Dec 1;30(23):2623-2636. doi: 10.1101/gad.290346.116.

    PMID: 28007785
  • High expression of TRF2, SOX10, and CD10 in circulating tumor microemboli detected in metastatic melanoma patients. A potential impact for the assessment of disease aggressiveness

    Long E, Ilie M, Bence C, Butori C, Selva E, Lalvée S, Bonnetaud C, Poissonnet G, Lacour JP, Bahadoran P, Brest P, Gilson E, Ballotti R, Hofman V, Hofman P.

    Cancer Med. 2016 Jun;5(6):1022-30. doi: 10.1002/cam4.661

    PMID: 26945789


  • Understanding why we age and how: Evolutionary biology meets different model organisms and multi-level omics: Meeting report on "Comparative Biology of Aging," Roscoff, October 12-16, 2015

    Gilson E, Bosch TC

    Bioessays. 2016 Jun;38(6):494-7

    PMID: 27119822

  • HR23b expression is a potential predictive biomarker for HDAC inhibitor treatment in mesenchymal tumours and is associated with response to vorinostat.

    Angelika Ihle M, Merkelbach-Bruse S, Hartmann W, Bauer S, Ratner N, Sonobe H, Nishio J, Larsson O, Åman P, Pedeutour F, Taguchi T, Wardelmann E, Buettner R, Schildhaus HU.

    J Pathol Clin Res. 2016 Feb 5;2(2):59-71. doi: 10.1002/cjp2.35. eCollection 2016 Apr.

    PMID: 27499916
  • Clinical effect of molecular methods in sarcoma diagnosis (GENSARC): a prospective, multicentre, observational study.

    Italiano A, Di Mauro I, Rapp J, Pierron G, Auger N, Alberti L, Chibon F, Escande F, Voegeli AC, Ghnassia JP, Keslair F, Laé M, Ranchère-Vince D, Terrier P, Baffert S, Coindre JM, Pedeutour F.

    Lancet Oncol. 2016 Apr;17(4):532-538. doi: 10.1016/S1470-2045(15)00583-5. Epub 2016 Mar 10.

    PMID: 26970672
  • Three Rounds of External Quality Assessment in France to Evaluate the Performance of 28 Platforms for Multiparametric Molecular Testing in Metastatic Colorectal and Non-Small Cell Lung Cancer.

    Dequeker EM, Keppens C, Egele C, Delen S, Lamy A, Lemoine A, Sabourin JC, Andrieu C, Ligtenberg M, Fetique D, Tops B, Descarpentries C, Blons H, Denoux Y, Aube C, Penault-Llorca F, Hofman P, Leroy K, Le Marechal C, Doucet L, Duranton-Tanneur V, Pedeutour F, Soubeyran I, Côté JF, Emile JF, Vignaud JM, Monhoven N, Haddad V, Laurent-Puig P, van Krieken H, Nowak F, Lonchamp E, Bellocq JP, Rouleau E.

    J Mol Diagn. 2016 Mar;18(2):205-14. doi: 10.1016/j.jmoldx.2015.09.004. Epub 2016 Jan 2.

    PMID: 26752307
  • MET immunolabeling is a useful predictive tool for MET gene amplification in glioblastoma.

    Burel-Vandenbos F, Ngo-Mai M, Dadone B, Di Mauro I, Gimet S, Saada-Bouzid E, Bourg V, Almairac F, Fontaine D, Virolle T, Pedeutour F.

    Neuropathol Appl Neurobiol. 2017 Apr;43(3):252-266. doi: 10.1111/nan.12320. Epub 2016 Apr 4.

    PMID: 26946354
  • Reply: High prevalence of CHCHD10 mutations in patients with frontotemporal dementia from China

    Bannwarth S, Ait-El-Mkadem S, Chaussenot A, Genin EC, Lacas-Gervais S, Fragaki K, Berg-Alonso L, Kageyama Y, Serre V, Moore D, Verschueren A, Rouzier C, Le Ber I, Augé G, Cochaud C, Lespinasse F, N'Guyen K, de Septenville A, Brice A, Yu-Wai-Man P, Sesaki H, Pouget J, Paquis-Flucklinger V.

    Brain. 2016 Apr;139(Pt 4):e22.

    PMID: 26719380

  • Extensive Recombination of a Yeast Diploid Hybrid through Meiotic Reversion

    Laureau R, Loeillet S, Salinas F, Bergström A, Legoix-Né P, Liti G, Nicolas A.

    PLoS Genet. 2016 Feb 1;12(2):e1005781. doi: 10.1371/journal.pgen.1005781.

    PMID: 26828862

  • BCL-B (BCL2L10) is overexpressed in patients suffering from multiple myeloma (MM) and drives an MM-like disease in transgenic mice.

    Hamouda MA, Jacquel A, Robert G, Puissant A, Richez V, Cassel R, Fenouille N, Roulland S, Gilleron J, Griessinger E, Dubois A, Bailly-Maitre B, Goncalves D, Mallavialle A, Colosetti P, Marchetti S, Amiot M, Gomez-Bougie P, Rochet N, Deckert M, Avet-Loiseau H, Hofman P, Karsenti JM, Jeandel PY, Blin-Wakkach C, Nadel B, Cluzeau T, Anderson KC, Fuzibet JG, Auberger P, Luciano F.

    J Exp Med. 2016 Aug 22;213(9):1705-22.

    doi: 10.1084/jem.20150983. Epub 2016 Jul 25.

    PMID: 27455953;

    Pubmed Central PMCID: PMC4995074.

  • Amino Acid Transport Associated to Cluster of Differentiation 98 Heavy Chain (CD98hc) Is at the Cross-road of Oxidative Stress and Amino Acid Availability

    J Biol Chem. 2016 Apr 29;291(18):9700-11. doi: 10.1074/jbc.M115.704254. Epub 2016 Mar 5.

    PMID: 26945935
  • Virus-derived DNA drives mosquito vector tolerance to arboviral infection

    Goic B, Stapleford KA, Frangeul L, Doucet AJ, Gausson V, Blanc H, Schemmel-Jofre N, Cristofari G, Lambrechts L, Vignuzzi M, Saleh MC.

    Nat Commun. 2016 Sep 1;7:12410.


  • TERT promoter mutations in pancreatic endocrine tumours are rare and mainly found in tumours from patients with hereditary syndromes.

    Vinagre J, Nabais J, Pinheiro J, Batista R, Oliveira RC, Gonçalves AP, Pestana A, Reis M, Mesquita B, Pinto V, Lyra J, Cipriano MA, Ferreira MG, Lopes JM, Sobrinho-Simões M, Soares P.

    Scientific reports. 2016; 6:29714.

    PMID: 27411289
  • Activation of individual L1 retrotransposon instances is restricted to cell-type dependent permissive loci.


    Philippe C, Vargas-Landin DB, Doucet AJ, van Essen D, Vera-Otarola J, Kuciak M, Corbin A, Nigumann P, Cristofari G.

    Elife. 2016 Mar 26;5. pii: e13926. doi: 10.7554/eLife.13926.

  • Comparative analysis of micro-RNAs in human papillomavirus-positive versus -negative oropharyngeal cancers.

    Mirghani H, Ugolin N, Ory C, Goislard M, Lefèvre M, Baulande S, Hofman P, Guily JL, Chevillard S, Lacave R.

    Head Neck. 2016 Nov;38(11):1634-1642.

    doi: 10.1002/hed.24487. Epub 2016 Apr 21.

    PMID: 27097597.

  • Rebuttal from Dr. Hofman and Dr. Ilié.

    Ilié M, Hofman P.

    Transl Lung Cancer  Res. 2016 Aug;5(4):428-9.

    doi: 10.21037/tlcr.2016.08.05.

    PMID: 27657908;

    PubMed Central PMCID: PMC5009090.

  • Pros: Can tissue biopsy be replaced by liquid biopsy?

    Ilié M, Hofman P.

    Transl Lung Cancer Res. 2016 Aug;5(4):420-3.

    doi: 10.21037/tlcr.2016.08.06.

    PMID: 27655109;

    Pubmed Central PMCID: PMC5009092.

  • Compounds Triggering ER Stress Exert Anti-Melanoma Effects and Overcome BRAF Inhibitor Resistance.

    Cerezo M, Lehraiki A, Millet A, Rouaud F, Plaisant M, Jaune E, Botton T, Ronco C, Abbe P, Amdouni H, Passeron T, Hofman V, Mograbi B, Dabert-Gay AS, Debayle D, Alcor D, Rabhi N, Annicotte JS, Héliot L, Gonzalez-Pisfil M, Robert C, Moréra S, Vigouroux A, Gual P, Ali MMU, Bertolotto C, Hofman P, Ballotti R, Benhida R, Rocchi S.

    Cancer Cell. 2016 Jul 11;30(1):183.

    doi:  10.1016/j.ccell.2016.06.007. Epub 2016 Jul 11.

    PMID: 27479035.

  • Telomeres in aging and disease: lessons from zebrafish.

    Carneiro MC, de Castro IP, Ferreira MG.

    Disease models & mechanisms. 2016; 9(7):737-48.

    PMID: 27482813
  • PD-L1 expression in basaloid squamous cell lung carcinoma: Relationship to PD-1(+) and CD8(+) tumor-infiltrating T cells and outcome.

    Ilie M, Falk AT, Butori C, Chamorey E, Bonnetaud C, Long E, Lassalle S, Zahaf K, Vénissac N, Mouroux J, Cohen C, Brambilla E, Marquette CH, Hofman V, Hofman P.

    Mod Pathol. 2016 Dec;29(12):1552-1564.

    doi: 10.1038/modpathol.2016.149. Epub 2016 Aug 26.

    PMID: 27562497.

  • RNA Activation of the Vascular Endothelial Growth Factor Gene (VEGF) Promoter by Double-Stranded RNA and Hypoxia: Role of Noncoding VEGF Promoter Transcripts.

    Lopez P, Wagner KD, Hofman P, Van Obberghen E.

    Mol Cell Biol. 2016 May 2;36(10):1480-93.

    doi: 10.1128/MCB.01096-15. Print 2016 May 15.

    PMID: 26976645;

    Pubmed Central PMCID: PMC4859685.

  • The body's tailored suit: Skin as a mechanical interface

    Tissot FS, Boulter E, Estrach S, Féral CC.

    Eur J Cell Biol. 2016 Nov;95(11):475-482.

    PMID: 27461124

  • MicroRNA-375/SEC23A as biomarkers of the in vitro efficacy of vandetanib.

    Lassalle S, Zangari J, Popa A, Ilie M, Hofman V, Long E, Patey M, Tissier F, Belléannée G, Trouette H, Catargi B, Peyrottes I, Sadoul JL, Bordone O, Bonnetaud C, Butori C, Bozec A, Guevara N, Santini J, Hénaoui IS, Lemaire G, Blanck O, Vielh P, Barbry P, Mari B, Brest P, Hofman P.

    Oncotarget. 2016 May 24;7(21):30461-78.

    doi: 10.18632/oncotarget.8458.

    PMID: 27036030;

    Pubmed Central PMCID: PMC5058693.

  • Pathologists and liquid biopsies: to be or not to be?

    Hofman P, Popper HH.

    Virchows Arch. 2016 Dec;469(6):601-609. Epub 2016 Aug 23. Review.

    Pubmed PMID:

  •  [Issues and current limits for immunohistochemical assessment of PD-L1 status in bronchial biopsies].

    Hofman V, Ilie M, Long E, Butori C, Lassalle S, Washetine K, Lalve S, Marquette CH, Soria JC, Hofman P.

    Bull Cancer. 2016 Apr;103(4):368-80.

    doi: 10.1016/j.bulcan.2016.01.014. Epub 2016 Feb  23. Review. French.

    PMID: 26920041.

  • Biochemical Approaches to Study LINE-1 Reverse Transcriptase Activity In Vitro.

    Viollet S, Doucet AJ, Cristofari G.

    Methods Mol Biol. 2016;1400:357-76.

    PMID: 26895064
  • Short Telomeres in Key Tissues Initiate Local and Systemic Aging in Zebrafish.

    Carneiro MC, Henriques CM, Nabais J, Ferreira T, Carvalho T, Ferreira MG.
    PLoS genetics. 2016; 12(1):e1005798.
    PMID: 26789415

  • A case report of isolated lymphadenopathy revealing localized leishmanial lymphadenopathy in an asthenic 25-year-old man.

    Hurlot Q, Fillaux J, Laurent C, Berry A, Hofman P, Marchou B, Delobel P, Brousset P, Martin-Blondel G.

    Medicine (Baltimore). 2016 Jul;95(29):e3932.

    doi: 10.1097/MD.0000000000003932.

    PMID: 27442631;

    Pubmed Central PMCID: PMC5265748.


  • [Standard of care of carcinomas on cancer of unknown primary site in 2016].

    Benderra MA, Ilié M, Hofman P, Massard C.

    Bull Cancer. 2016 Jul-Aug;103(7-8):697-705.

    doi: 10.1016/j.bulcan.2016.05.003. Epub 2016 Jun 29. French.

    PMID: 27372228.

  • Excess sphingomyelin disturbs ATG9A trafficking and autophagosome closure.

    Corcelle-Termeau E, Vindeløv SD, Hämälistö S, Mograbi B, Keldsbo A, Bräsen JH, Favaro E, Adam D, Szyniarowski P, Hofman P, Krautwald S, Farkas T, Petersen NH, Rohde M, Linkermann A, Jäättelä M.

    Autophagy. 2016 May 3;12(5):833-49.

    doi: 10.1080/15548627.2016.1159378. Epub 2016 Apr 12.

    PMID: 27070082;

    Pubmed Central PMCID: PMC4854555.

  • Post-Transcriptional Control of LINE-1 Retrotransposition by Cellular Host Factors in Somatic Cells.

    Pizarro JG, Cristofari G.

    Front Cell Dev Biol. 2016 Mar 7;4:14. Review.

    PMID: 27014690 

  • Virus-derived DNA drives mosquito vector tolerance to arboviral infection.

    Goic B, Stapleford KA, Frangeul L, Doucet AJ, Gausson V, Blanc H, Schemmel-Jofre N, Cristofari G, Lambrechts L, Vignuzzi M, Saleh MC.

    Nat Commun. 2016 Sep 1;7:12410.

    PMID: 27580708

  • International Congress on Transposable elements (ICTE 2016) in Saint Malo: mobile elements under the sun of Brittany.

    Lesage P, Bétermier M, Bridier-Nahmias A, Chandler M, Chambeyron S, Cristofari G, Gilbert N, Quesneville H, Vaury C, Volff JN.

    Mob DNA. 2016 Oct 20;7:19. Meeting Report.

    PMID: 30044887
  • High expression of TRF2, SOX10, and CD10 in circulating tumor microemboli detected in metastatic melanoma patients. A potential impact for the  assessment of disease aggressiveness.

    Long E, Ilie M, Bence C, Butori C, Selva E, Lalvée S, Bonnetaud C, Poissonnet G, Lacour JP, Bahadoran P, Brest P, Gilson E, Ballotti R, Hofman V, Hofman P.

    Cancer Med. 2016 Jun;5(6):1022-30.

    doi: 10.1002/cam4.661. Epub 2016 Mar 6.

    PMID: 26945789;

    Pubmed Central PMCID: PMC4924359.

  • KRAS Mutations in Lung Adenocarcinoma: Molecular and Epidemiological Characteristics, Methods for Detection, and Therapeutic Strategy Perspectives.

    Guibert N, Ilie M, Long E, Hofman V, Bouhlel L, Brest P, Mograbi B, Marquette CH, Didier A, Mazieres J, Hofman P.

    Curr Mol Med. 2015;15(5):418-32. Review.

    PMID: 25941815.

  • Elucidating the molecular architecture of adaptation via evolve and resequence experiments

    Long A, Liti G, Luptak A, Tenaillon O.

    Nat Rev Genet. 2015 Oct;16(10):567-82. doi: 10.1038/nrg3937.

    PMID: 26347030

  • Characterization of Morphological and Cellular Events Underlying Oral Regeneration in the Sea Anemone, Nematostella vectensis

    Amiel AR, Johnston HT, Nedoncelle K, Warner JF, Ferreira S, Röttinger E.

    Int J Mol Sci. 2015 Dec 1;16(12):28449-71.

    PMID: 26633371

  • Deletion of the Saccharomyces cerevisiae ARO8 gene, encoding an aromatic amino acid transaminase, enhances phenylethanol production from glucose

    Romagnoli G, Knijnenburg TA, Liti G, Louis EJ, Pronk JT, Daran JM.

    Yeast. 2015 Jan;32(1):29-45. doi: 10.1002/yea.3015.

    PMID: 24733517

  • Saccharomyces pastorianus: genomic insights inspiring innovation for industry

    Gibson B, Liti G.

    Yeast. 2015 Jan;32(1):17-27. doi: 10.1002/yea.3033.

    PMID: 25088523

  • Concerted evolution of life stage performances signals recent selection on yeast nitrogen use

    Ibstedt S, Stenberg S, Bagés S, Gjuvsland AB, Salinas F, Kourtchenko O, Samy JK, Blomberg A, Omholt SW, Liti G, Beltran G, Warringer J.

    Mol Biol Evol. 2015 Jan;32(1):153-61. doi: 10.1093/molbev/msu285.

    PMID: 25349282

  • Genetic and pharmacological inactivation of the purinergic P2RX7 receptor dampens inflammation but increases tumor incidence in a mouse model of colitis-associated cancer.

    Hofman P, Cherfils-Vicini J, Bazin M, Ilie M, Juhel T, Hébuterne X, Gilson E, Schmid-Alliana A, Boyer O, Adriouch S, Vouret-Craviari V.

    Cancer Res. 2015 Mar 1;75(5):835-45.

    doi: 10.1158/0008-5472.CAN-14-1778.  Epub 2015 Jan 6.

    PMID: 25564520.

  • Diet-induced hypoxia responsive element demethylation increases CEACAM6 expression, favouring Crohn's disease-associated Escherichia coli colonisation.

    Denizot J, Desrichard A, Agus A, Uhrhammer N, Dreux N, Vouret-Craviari V, Hofman P, Darfeuille-Michaud A, Barnich N.

    Gut. 2015 Mar;64(3):428-37.

    doi: 10.1136/gutjnl-2014-306944. Epub 2014 Jun 4.

    PMID: 24898815.

  • Immunohistochemistry as a potential tool for routine detection of the NRAS Q61R mutation in patients with metastatic melanoma.

    Ilie M, Long-Mira E, Funck-Brentano E, Lassalle S, Butori C, Lespinet-Fabre  V, Bordone O, Gay A, Zahaf K, Poissonnet G, Lacour JP, Bahadoran P, Ballotti R, Gros A, Dutriaux C, Saiag P, Merlio JP, Vergier B, Emile JF, Hofman V, Hofman P. 

    J Am Acad Dermatol. 2015 May;72(5):786-93.

    doi: 10.1016/j.jaad.2015.01.012. Epub 2015 Feb 7.

    PMID: 25659223.

  • TRF2 acts as a transcriptional regulator in tumor angiogenesis.

    Maï ME, Wagner KD, Michiels JF, Gilson E,* Wagner N.

    Mol Cell Oncol. 2015 Jan 23;2(3):e988508

    PMID: 27308469

  • Telomere length is a prognostic biomarker in elderly advanced ovarian cancer patients: a multicenter GINECO study

    Falandry C, Horard B, Bruyas A, Legouffe E, Cretin J, Meunier J, Alexandre J, Delecroix V, Fabbro M, Certain MN, Maraval-Gaget R, Pujade-Lauraine E, Gilson E, Freyer G

    Aging (Albany NY), 2015, Dec;7(12):1066-76

    PMID: 26638179

  • Intragenic G-quadruplex structure formed in the human CD133 and its biological and translational relevance

    Zizza P, Cingolani C, Artuso S, Salvati E, Rizzo A, D'Angelo C, Porru M, Pagano B, Amato J, Randazzo A, Novellino E, Stoppacciaro A, Gilson E, Stassi G, Leonetti C, Biroccio A.

    Nucleic Acids Res., 2015, Oct27.pii: gkv1122

    PMID: 26511095

  • TRF1 and TRF2 binding to telomeres is modulated by nucleosomal organization.

    Galati A, Micheli E, Alicata C, Ingegnere T, Cicconi A, Pusch MC, Giraud-Panis MJ, Gilson E, Cacchione S.

    Nucleic Acids Res., 2015, Jul13;43(12):5824-37

    PMID: 25999344

  • Resistance to sunitinib in renal clear cell carcinoma results from sequestration in lysosomes and inhibition of the autophagic flux.

    Giuliano S, Cormerais Y, Dufies M, Grépin R, Colosetti P, Belaid A, Parola J, Martin A, Lacas-Gervais S, Mazure NM, Benhida R, Auberger P, Mograbi B, Pagès G.

    Autophagy. 2015 ;11(10):1891-904. doi: 10.1080/15548627.2015.1085742.

    PMID: 26312386; PubMed Central PMCID: PMC4824581.

  • Epigenetic switch drives the conversion of fibroblasts into proinvasive cancer-associated fibroblasts.

    Albrengues J, Bertero T, Grasset E, Bonan S, Maiel M, Bourget I, Philippe C, Herraiz Serrano C, Benamar S, Croce O, Sanz-Moreno V, Meneguzzi G, Feral CC, Cristofari G, Gaggioli C.

    Nat Commun. 2015 Dec 15;6:10204. 

    PMID: 26667266
  • Analysis of a spatial gene expression database for sea anemone Nematostella vectensis during early development

    Botman D, Jansson F, Röttinger E, Martindale MQ, de Jong J, Kaandorp JA.

    BMC Syst Biol. 2015 Sep 24;9:63.

    PMID: 26400098

  • Spatio-temporal genetic heterogeneity of CTNNB1 mutations in sporadic desmoid type fibromatosis lesions.

    Doyen J, Duranton-Tanneur V, Hostein I, Karanian-Philippe M, Chevreau C, Breibach F, Coutts M, Dadone B, Saint-Paul MC, Gugenheim J, Duffaud F, Pedeutour F.

    Virchows Arch. 2016 Mar;468(3):369-74. doi: 10.1007/s00428-015-1883-8. Epub 2015 Dec 14.

    PMID: 26666421
  • ATG18 and FAB1 are involved in dehydration stress tolerance in Saccharomyces cerevisiae

    López-Martínez G, Margalef-Català M, Salinas F, Liti G, Cordero-Otero R.

    PLoS One. 2015 Mar 24;10(3):e0119606. doi: 10.1371/journal.pone.0119606.

    PMID: 25803831

  • euL1db: the European database of L1HS retrotransposon insertions in humans.

    Mir AA, Philippe C, Cristofari G.

    Nucleic Acids Res. 2015 Jan;43(Database issue):D43-7.

    PMID: 25352549
  • Dismantling papillary renal cell carcinoma classification: The heterogeneity of genetic profiles suggests several independent diseases.

    Marsaud A, Dadone B, Ambrosetti D, Baudoin C, Chamorey E, Rouleau E, Lefol C, Roussel JF, Fabas T, Cristofari G, Carpentier X, Michiels JF, Amiel J, Pedeutour F.

    Genes Chromosomes Cancer. 2015 Jun;54(6):369-82.

    PMID: 25820192
  • Brucella Intracellular Life Relies on the Transmembrane Protein CD98 Heavy Chain

    Keriel A, Botella E, Estrach S, Bragagnolo G, Vergunst AC, Feral CC, O'Callaghan D.

    J Infect Dis. 2015 Jun 1;211(11):1769-78. doi: 10.1093/infdis/jiu673. Epub 2014 Dec 11.


  • The topoisomerase II catalytic inhibitor ICRF-193 preferentially targets telomeres that are capped by TRF2.

    Chen L, Zhu X, Zou Y, Xing J, Gilson E, Lu Y, Ye J

    Am. J. Physiol. Cell. Physiol., 2015, Mar1 ;308(5) :C372-7

    PMID: 25518961


  • Angiomatoid fibrous histiocytoma in children: 6 cases

    Bohelay G, Kluger N, Battistella M, Biaggi-Frassati A, Plantier F, Harraudeau A, Avril MF, Pedeutour F, Fraitag S.

    Ann Dermatol Venereol. 2015 Oct;142(10):541-8. doi: 10.1016/j.annder.2015.07.007. Epub 2015 Sep 9. Review. French.

    PMID: 26363999
  • Syndecan-1 regulates adipogenesis: new insights in dedifferentiated liposarcoma tumorigenesis.

    Zaragosi LE, Dadone B, Michiels JF, Marty M, Pedeutour F, Dani C, Bianchini L.

    Carcinogenesis. 2015 Jan;36(1):32-40. doi: 10.1093/carcin/bgu222. Epub 2014 Oct 24.

    PMID: 25344834
  • Fluorescence in situ hybridization analysis is a helpful test for the diagnosis of dermatofibrosarcoma protuberans.

    Karanian M, Pérot G, Coindre JM, Chibon F, Pedeutour F, Neuville A.

    Mod Pathol. 2015 Feb;28(2):230-7. doi: 10.1038/modpathol.2014.97. Epub 2014 Aug 1.

    PMID: 25081750
  • Prognostic value of HMGA2, CDK4, and JUN amplification in well-differentiated and dedifferentiated liposarcomas.

    Saâda-Bouzid E, Burel-Vandenbos F, Ranchère-Vince D, Birtwisle-Peyrottes I, Chetaille B, Bouvier C, Château MC, Peoc'h M, Battistella M, Bazin A, Gal J, Michiels JF, Coindre JM, Pedeutour F, Bianchini L.

    Mod Pathol. 2015 Nov;28(11):1404-14. doi: 10.1038/modpathol.2015.96. Epub 2015 Sep 4.

    PMID: 26336885
  • An open data ecosystem for cell migration research.

    Masuzzo P, Martens L; 2014 Cell Migration Workshop Participants, Ampe C, Anderson KI, Barry J, De Wever O, Debeir O, Decaestecker C, Dolznig H, Friedl P, Gaggioli C, Geiger B, Goldberg IG, Horn E, Horwitz R, Kam Z, Le Dévédec SE, Vignjevic DM, Moore J, Olivo-Marin JC, Sahai E, Sansone SA, Sanz-Moreno V, Strömblad S, Swedlow J, Textor J, Van Troys M, Zantl R.

    Trends Cell Biol. 2015 Feb;25(2):55-8.

    PMID: 25484346
  • Molecular cytogenetics of pediatric adipocytic tumors.

    Dadone B, Refae S, Lemarié-Delaunay C, Bianchini L, Pedeutour F.

    Cancer Genet. 2015 Oct;208(10):469-81. doi: 10.1016/j.cancergen.2015.06.005. Epub 2015 Jun 26. Review.

    PMID: 26319758
  • SRC inhibition represents a potential therapeutic strategy in liposarcoma.

    Sievers E, Trautmann M, Kindler D, Huss S, Gruenewald I, Dirksen U, Renner M, Mechtersheimer G, Pedeutour F, Åman P, Nishio J, Schildhaus HU, Kirfel J, Schirmacher P, Wardelmann E, Buettner R, Hartmann W.

    Int J Cancer. 2015 Dec 1;137(11):2578-88. doi: 10.1002/ijc.29645. Epub 2015 Jul 6.

    PMID: 26084847
  • Hemichordata

    Kaul-Strehlow S, Röttinger E

    In: Evolutionary Developmental Biology of Invertebrates 6: Deuterostomia

    Editor: Andreas Wanninger. Springer-Verlag GMBH / Vienna, 2015

    DOI 10.1007/978-3-7091-1856-6_2

  • Nodal signaling is required for mesodermal and ventral but not for dorsal fates in the indirect developing hemichordate, Ptychodera flava

    Röttinger E@, DuBuc TQ, Amiel AR, Martindale MQ.

    Biol Open. 2015 May 15;4(7):830-42.

    PMID: 25979707

    @ co-corresponding

  • Regulation of stimulus-inducible gene expression in myeloid cells

    Saccani S, Trabucchi M.

    Semin Immunol. 2015 Feb;27(1):33-43.

    PMID: 25820127
  • Domain analysis of the Nematostella vectensis SNAIL ortholog reveals unique nucleolar localization that depends on the zinc-finger domains

    Dattoli AA, Hink MA, DuBuc TQ, Teunisse BJ, Goedhart J, Röttinger E, Postma M.

    Sci Rep. 2015 Jul 20;5:12147.

    PMID: 26190255

  • The fascinating and secret wild life of the budding yeast S. cerevisiae

    Liti G.

    Elife. 2015 Mar 25;4. doi: 10.7554/eLife.05835.

    PMID: 25807086

  • Knock out of the BASIGIN/CD147 chaperone of lactate/H+ symporters disproves its pro-tumour action via extracellular matrix metalloproteases (MMPs) induction.

    Marchiq I, Albrengues J, Granja S, Gaggioli C, Pouysségur J, Simon MP.

    Oncotarget. 2015 Sep 22;6(28):24636-48. 

    PMID: 26284589
  • Interactions of Melanoma Cells with Distal Keratinocytes Trigger Metastasis via Notch Signaling Inhibition of MITF.

    Golan T, Messer AR, Amitai-Lange A, Melamed Z, Ohana R, Bell RE, Kapitansky O, Lerman G, Greenberger S, Khaled M, Amar N, Albrengues J, Gaggioli C, Gonen P, Tabach Y, Sprinzak D, Shalom-Feuerstein R, Levy C.

    Mol Cell. 2015 Aug 20;59(4):664-76. 

    PMID: 26236014
  • A basal level of DNA damage and telomere deprotection increases the sensitivity of cancer cells to G-quadruplex interactive compounds.

    Salvati E, Rizzo A, Iachettini S, Zizza P, Cingolani C, D’Angelo C, Porru M, Mondello C, Aiello A, Farsetti A, Gilson E, Leonetti C, Biroccio A.

    Nucleic Acids Res., 2015, Feb18 ;43(3) :1759-69

    PMID: 25618850

  • Attenuation of p38α MAPK stress response signaling delays the in vivo aging of skeletal muscle myofibers and progenitor cells

    Papaconstantinou J, Wang CZ, Zhang M, Yang S, Deford J, Bulavin DV, Ansari NH.
    Aging (Albany NY), 2015, Sep;7(9):718-33

  • Letter to the Editor on a paper by Hsiao C-T, Tsai P-C, Liao Y-C, Lee Y-C, Soong B-W. C9ORF72 repeat expansion is not a significant cause of late-onset cerebellar ataxia syndrome

    Plutino M, Chaussenot A, Ait-El-Mkadem S, Bannwarth S, Genin EC, Rouzier C, Augé G, Sacconi S, Pouget J, Paquis-Flucklinger V.

    J Neurol Sci. 2015 Apr 15;351(1-2):196-197.

    PMID: 25732802 

  • Autophagy : Moving Benchside Promises to Patient Bedsides.

    Belaid A, Ndiaye PD, Filippakis H, Roux J, Röttinger É, Graba Y, Brest P, Hofman P, Mograbi B.

    Curr Cancer Drug Targets. 2015;15(8):684-702. Review.

    PMID: 26452384.

  • De novo 4q duplication/deletion in a fetus with a congenital heart defect

    Dayem-Quere M, Giuliano F, Massol C, Piche M, Paquis-Flucklinger V, Karmous-Benailly H.

    Am J Med Genet A. 2015 Aug;167A(8):1932-6.

    PMID: 26097191

  • CHCHD10-Related Disorders

    Ait-El-Mkadem S, Chaussenot A, Bannwarth S, Rouzier C, Paquis-Flucklinger V.

    In: Adam MPArdinger HHPagon RAWallace SEBean LJHStephens KAmemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2019. 2015 Jul 1.

    PMID: 26131548

  • Reply: A distinct clinical phenotype in a German kindred with motor neuron disease carrying a CHCHD10 mutation

    Bannwarth S, Ait-El-Mkadem S, Chaussenot A, Genin EC, Lacas-Gervais S, Fragaki K, Berg-Alonso L, Kageyama Y, Serre V, Moore D, Verschueren A, Rouzier C, Le Ber I, Augé G, Cochaud C, Lespinasse F, N'Guyen K, de Septenville A, Brice A, Yu-Wai-Man P, Sesaki H, Pouget J, Paquis-Flucklinger V.

    Brain. 2015 Sep;138(Pt 9):e377

    PMID: 25681413 

  • Reply: Is CHCHD10 Pro34Ser pathogenic for frontotemporal dementia and amyotrophic lateral sclerosis?

    Bannwarth S, Ait-El-Mkadem S, Chaussenot A, Genin EC, Lacas-Gervais S, Fragaki K, Berg-Alonso L, Kageyama Y, Serre V, Moore D, Verschueren A, Rouzier C, Le Ber I, Augé G, Cochaud C, Lespinasse F, N'Guyen K, de Septenville A, Brice A, Yu-Wai-Man P, Sesaki H, Pouget J, Paquis-Flucklinger V.

    Brain. 2015 Oct;138(Pt 10):e386. 

    PMID: 25953779

  • CHCHD10 mutations are not a common cause of SMN1-negative type III/IV spinal motor atrophy

    Morel G, Rouzier C, Chaussenot A, Ait-El-Mkadem S, Bannwarth S, Genin EC, Augé G, Chabrol B, Pouget J, Soriani MH, Sacconi S, Paquis-Flucklinger V.

    Ann Neurol. 2015 Nov;78(5):831.

    PMID: 26095063

  • Local mitochondrial-endolysosomal microfusion cleaves voltage-dependent anion channel 1 to promote survival in hypoxia.

    Brahimi-Horn MC, Lacas-Gervais S, Adaixo R, Ilc K, Rouleau M, Notte A, Dieu  M, Michiels C, Voeltzel T, Maguer-Satta V, Pelletier J, Ilie M, Hofman P, Manoury B, Schmidt A, Hiller S, Pouysségur J, Mazure NM.

    Mol Cell Biol. 2015 May;35(9):1491-505.

    doi: 10.1128/MCB.01402-14. Epub 2015 Feb 17.

    PMID: 25691661;

    Pubmed Central PMCID: PMC4387213.

  • Mutation update and uncommon phenotypes in a French cohort of 96 patients with WFS1-related disorders

    Chaussenot A, Rouzier C, Quere M, Plutino M, Ait-El-Mkadem S, Bannwarth S, Barth M, Dollfus H, Charles P, Nicolino M, Chabrol B, Vialettes B, Paquis-Flucklinger V.

    Clin Genet. 2015 May;87(5):430-9.

    PMID: 24890733 

  • French multicentric validation of ALK rearrangement diagnostic in 547 lung adenocarcinomas.

    Lantuejoul S, Rouquette I, Blons H, Le Stang N, Ilie M, Begueret H, Grégoire V, Hofman P, Gros A, Garcia S, Monhoven N, Devouassoux-Shisheboran M, Mansuet-Lupo A, Thivolet F, Antoine M, Vignaud JM, Penault-Llorca F, Galateau-Sallé F, McLeer-Florin A.

    Eur Respir J. 2015 Jul;46(1):207-18.

    doi: 10.1183/09031936.00119914. Epub 2015 Apr 30.

    PMID: 25929957.

  • Reply: CHCHD10 mutations in Italian patients with sporadic amyotrophic lateral sclerosis

    Bannwarth S, Ait-El-Mkadem S, Chaussenot A, Genin EC, Lacas-Gervais S, Fragaki K, Berg-Alonso L, Kageyama Y, Serre V, Moore D, Verschueren A, Rouzier C, Le Ber I, Augé G, Cochaud C, Lespinasse F, N'Guyen K, de Septenville A, Brice A, Yu-Wai-Man P, Sesaki H, Pouget J, Paquis-Flucklinger V.

    Brain. 2015 Aug;138(Pt 8):e373.

    PMID: 25576309 

  • Stratification of resectable lung adenocarcinoma by molecular and pathological risk estimators.

    Rakha E, Pajares MJ, Ilie M, Pio R, Echeveste J, Hughes E, Soomro I, Long E, Idoate MA, Wagner S, Lanchbury JS, Baldwin DR, Hofman P, Montuenga LM.

    Eur J Cancer. 2015 Sep;51(14):1897-903.

    doi: 10.1016/j.ejca.2015.07.015. Epub 2015 Jul 30.

    PMID: 26235745.

  • Sense and nonsense in the process of accreditation of a pathology laboratory.

    Long-Mira E, Washetine K, Hofman P.

    Virchows Arch. 2016 Jan;468(1):43-9.

    doi: 10.1007/s00428-015-1837-1. Epub 2015 Sep 3. Review.

    PMID: 26334197.

  • An overview of neurological and neuromuscular signs in mitochondrial diseases

    Chaussenot A, Paquis-Flucklinger V.

    Rev Neurol (Paris). 2014 May;170(5):323-38.

    PMID: 24792434

  • The relevance of testing the efficacy of anti-angiogenesis treatments on cells derived from primary tumors: a new method for the personalized treatment of renal cell carcinoma.

    Grépin R, Ambrosetti D, Marsaud A, Gastaud L, Amiel J, Pedeutour F, Pagès G.

    PLoS One. 2014 Mar 27;9(3):e89449. doi: 10.1371/journal.pone.0089449. eCollection 2014.

    PMID: 24676409
  • Reply: Two novel mutations in conserved codons indicate that CHCHD10 is a gene associated with motor neuron disease

    Bannwarth S, Ait-El-Mkadem S, Chaussenot A, Genin EC, Lacas-Gervais S, Fragaki K, Berg-Alonso L, Kageyama Y, Serre V, Moore D, Verschueren A, Rouzier C, Le Ber I, Augé G, Cochaud C, Lespinasse F, N'Guyen K, de Septenville A, Brice A, Yu-Wai-Man P, Sesaki H, Pouget J, Paquis-Flucklinger V.

    Brain. 2014 Dec;137(Pt 12):e310.

    PMID: 25113788

  • Screening of CHCHD10 in a French cohort confirms the involvement of this gene in frontotemporal dementia with amyotrophic lateral sclerosis patients

    Chaussenot A, Le Ber I, Ait-El-Mkadem S, Camuzat A, de Septenville A, Bannwarth S, Genin EC, Serre V, Augé G; French research network on FTD and FTD-ALS, Brice A, Pouget J, Paquis-Flucklinger V.

    Neurobiol Aging. 2014 Dec;35(12):2884.e1-2884.e4. 

    PMID: 25155093 

  • The architecture and evolution of cancer neochromosomes.

    Garsed DW, Marshall OJ, Corbin VD, Hsu A, Di Stefano L, Schröder J, Li J, Feng ZP, Kim BW, Kowarsky M, Lansdell B, Brookwell R, Myklebost O, Meza-Zepeda L, Holloway AJ, Pedeutour F, Choo KH, Damore MA, Deans AJ, Papenfuss AT, Thomas DM.

    Cancer Cell. 2014 Nov 10;26(5):653-67. doi: 10.1016/j.ccell.2014.09.010. Epub 2014 Nov 10.

    PMID: 25517748
  • CD98hc (SLC3A2) loss protects against ras-driven tumorigenesis by modulating integrin-mediated mechanotransduction.

    Estrach S, Lee SA, Boulter E, Pisano S, Errante A, Tissot FS, Cailleteau L, Pons C, Ginsberg MH, Féral CC.

    Cancer Res. 2014 Dec 1;74(23):6878-89. doi: 10.1158/0008-5472.CAN-14-0579. Epub 2014 Sep 29.


  • Reply: Are CHCHD10 mutations indeed associated with familial amyotrophic lateral sclerosis?

    Bannwarth S, Ait-El-Mkadem S, Chaussenot A, Genin EC, Lacas-Gervais S, Fragaki K, Berg-Alonso L, Kageyama Y, Serre V, Moore D, Verschueren A, Rouzier C, Le Ber I, Augé G, Cochaud C, Lespinasse F, N'Guyen K, de Septenville A, Brice A, Yu-Wai-Man P, Sesaki H, Pouget J, Paquis-Flucklinger V.

    Brain. 2014 Dec;137(Pt 12):e314. 

    PMID: 25348633 

  • A mitochondrial origin for frontotemporal dementia and amyotrophic lateral sclerosis through CHCHD10 involvement

    Bannwarth S, Ait-El-Mkadem S, Chaussenot A, Genin EC, Lacas-Gervais S, Fragaki K, Berg-Alonso L, Kageyama Y, Serre V, Moore DG, Verschueren A, Rouzier C, Le Ber I, Augé G, Cochaud C, Lespinasse F, N'Guyen K, de Septenville A, Brice A, Yu-Wai-Man P, Sesaki H, Pouget J, Paquis-Flucklinger V.

    Brain. 2014 Aug;137(Pt 8):2329-45. 

    PMID: 24934289

  • Quantitative multiplex PCR of short fluorescent fragments for the detection of large intragenic POLG rearrangements in a large French cohort

    Rouzier C, Chaussenot A, Serre V, Fragaki K, Bannwarth S, Ait-El-Mkadem S, Attarian S, Kaphan E, Cano A, Delmont E, Sacconi S, Mousson de Camaret B, Rio M, Lebre AS, Jardel C, Deschamps R, Richelme C, Pouget J, Chabrol B, Paquis-Flucklinger V.

    Eur J Hum Genet. 2014 Apr;22(4):542-50.

    PMID: 23921535 

  • The basic N-terminal domain of TRF2 limits recombination endonuclease action at human telomeres.

    Saint-Léger A, Koelblen M, Civitelli L, Bah A, Djerbi N, Giraud-Panis MJ, Londoño-Vallejo A, Ascenzioni F, Gilson E.

    Cell Cycle., 2014, Jun 26;13(15) 2469-74

    PMID: 25483196

  • The metabolic checkpoint kinase mTOR is essential for IL-15 signaling during the development and activation of NK cells.

    Marçais A, Cherfils-Vicini J, Viant C, Degouve S, Viel S, Fenis A, Rabilloud J, Mayol K, Tavares A, Bienvenu J, Gangloff YG, Gilson E, Vivier E, Walzer T.

    Nat. Immunol., 2014, Aug;15(8):749-57

    PMID: 24973821

  • BRAFV600E mutation analysis by immunohistochemistry in patients with thoracic metastases from colorectal cancer

    Ilie MI, Long-Mira E, Hofman V, Mouroux J, Vignaud JM, Gauchotte G, Begueret H, Merlio JP, Emile JF, Hébuterne X, Hofman P

    Pathology. 2014 Jun;46(4):311-5

    PMID: 24798160

  • L1 retrotransposition: The snap-velcro model and its consequences.

    Viollet S, Monot C, Cristofari G.

    Mob Genet Elements. 2014 Jan 1;4(1):e28907. Review.

    PMID: 24818067
  • A new KIT mutation (N505I) in acral melanoma confers constitutive signaling, favors tumorigenic properties, and is sensitive to imatinib

    Allegra M, Giacchero D, Segalen C, Dumaz N, Butori C, Hofman V, Hofman P, Lacour JP, Bertolotto C, Bahadoran P, Ballotti R

    J Invest Dermatol. 2014 May;134(5):1473-1476.

    PMID: 24317392

  • Autophagy and SQSTM1 on the RHOA(d) again: emerging roles of autophagy in the degradation of signaling proteins

    Belaid A, Ndiaye PD, Cerezo M, Cailleteau L, Brest P, Klionsky DJ, Carle GF, Hofman P, Mograbi B

    Autophagy. 2014 Feb;10(2):201-8

    PMID: 24300375

  • Public-private relationships in biobanking: a still underestimated key component of open innovation

    Hofman P, Bréchot C, Zatloukal K, Dagher G, Clément B

    Virchows Arch. 2014 Jan;464(1):3-9.

    PMID: 24337181

  • Detection of BRAF p.V600E Mutations in Melanoma by Immunohistochemistry Has a Good Interobserver Reproducibility

    Marin C, Beauchet A, Capper D, Zimmermann U, Julié C, Ilie M, Saiag P, von Deimling A, Hofman P, Emile JF.

    Arch Pathol Lab Med. 2014 Jan;138(1):71-5.

    PMID: 23651150

  • Detection of circulating tumor cells from lung cancer patients in the era of targeted therapy: promises, drawbacks and pitfalls

    Hofman V, Ilie M, Long E, Guibert N, Selva E, Washetine K, Mograbi B, Mouroux J, Vénissac N, Reverso-Meinietti J, Milano G, Mazières J, Marquette CH, Paterlini-Bréchot P, Hofman P.

    Curr Mol Med. 2014 May;14(4):440-56. Review.

    PMID: 24730524

  • Diagnostic value of immunohistochemistry for the detection of the BRAF(V600E) mutation in papillary thyroid carcinoma: comparative analysis with three DNA-based assays

    Ilie MI, Lassalle S, Long-Mira E, Bonnetaud C, Bordone O, Lespinet V, Lamy A, Sabourin JC, Haudebourg J, Butori C, Guevara N, Peyrottes I, Sadoul JL, Bozec  A, Santini J, Capper D, von Deimling A, Emile JF, Hofman V, Hofman P.

    Thyroid. 2014 May;24(5):858-66

    PMID: 24417277

  • Molecular classification of malignant pleural mesothelioma: identification of a poor prognosis subgroup linked to the epithelial-to-mesenchymal transition.

    de Reyniès A, Jaurand MC, Renier A, Couchy G, Hysi I, Elarouci N, Galateau-Sallé F, Copin MC, Hofman P, Cazes A, Andujar P, Imbeaud S, Petel F, Pairon JC, Le Pimpec-Barthes F, Zucman-Rossi J, Jean D.

    Clin Cancer Res. 2014 Mar 1;20(5):1323-34

    PMID: 24798160

  • LIF mediates proinvasive activation of stromal fibroblasts in cancer

    Albrengues J, Bourget I, Pons C, Butet V, Hofman P, Tartare-Deckert S, Feral CC, Meneguzzi G, Gaggioli C.

    Cell Rep. 2014 Jun 12;7(5):1664-1678

    PMID: 24857661

  • Successful re-treatment of a relapsed V600E mutated HCL patient with low-dose vemurafenib

    C Bailleux, Robert G, Ginet C, Re D, Thyss A, Sudaka I, Peyrottes I, Hofman P, Auberger P, Peyrade F.

    Oncoscience. 2014 Dec 26;2(1):44-9. eCollection 2015.

    PMID: 25815361

  • Effects of low-dose recombinant interleukin 2 to promote T-regulatory cells in alopecia areata.

    Castela E, Le Duff F, Butori C, Ticchioni M, Hofman P, Bahadoran P, Lacour JP, Passeron T.

    JAMA Dermatol. 2014 Jul;150(7):748-51

    PMID: 24872229

  • What place and what future for the pathology of infectious and tropical diseases in France?

    Hofman P

    Ann Pathol. 2014 Jun;34(3):171-82.

    PMID: 24950861

  • EFA6B antagonizes breast cancer

    Zangari J, Partisani M, Bertucci F, Milanini J, Bidaut G, Berruyer-Pouyet C, Finetti P, Long E, Brau F, Cabaud O, Chetaille B, Birnbaum D, Lopez M, Hofman P,  Franco M, Luton F.

    Cancer Res. 2014 Oct 1;74(19):5493-506

    PMID: 25115298.

  • A predictive transcriptomic signature of oropharyngeal cancer according to HPV16 status exclusively

    Mirghani H, Ugolin N, Ory C, Lefèvre M, Baulande S, Hofman P, St Guily JL, Chevillard S, Lacave R.

    Oral Oncol. 2014 Nov;50(11):1025-34

    PMID: 25156715

  • Sentinel" circulating tumor cells allow early diagnosis of lung cancer in patients with chronic obstructive pulmonary disease

    Ilie M, Hofman V, Long-Mira E, Selva E, Vignaud JM, Padovani B, Mouroux J, Marquette CH, Hofman P.

    PLoS One.  2014 Oct 31;9(10):e111597

    PMID: 25360587

  • Constitutive activation of the renin-angiotensin system reduces visceral fat and improves glucose tolerance in mice

    Favre GA, Lebrun P, Lopez P, Butori C, Hofman P, Esnault VL, Van Obberghen E.

    J Renin Angiotensin Aldosterone Syst. 2014 Dec;15(4):396-409

    PMID: 25371094.

  • Immunohistochemistry and personalised medicine in lung oncology: advantages and limitations

    Hofman V, Ilie M, Long E, Lassalle S, Butori C, Bence C, Washetine K, Lalvee S, Hofman P.

    Bull Cancer. 2014 Oct;101(10):958-65

    PMID: 25373695


  • HIF1A regulates xenophagic degradation of adherent and invasive Escherichia coli (AIEC).

    Mimouna S, Bazin M, Mograbi B, Darfeuille-Michaud A, Brest P, Hofman P, Vouret-Craviari V.

    Autophagy. 2014;10(12):2333-45.

    PMID: 25484075

  • Current challenges for detection of circulating tumor cells and cell-free circulating nucleic acids, and their characterization in non-small cell lung carcinoma patients. What is the best blood substrate for personalized medicine?

    Ilie M, Hofman V, Long E, Bordone O, Selva E, Washetine K, Marquette CH, Hofman P.

    Ann Transl Med. 2014 Nov;2(11):107

    PMID: 25489581

  • EU-US Expert Group on cost recovery in biobanks. Public biobanks: calculation and recovery of costs.

    Clément B, Yuille M, Zaltoukal K, Wichmann HE, Anton G, Parodi B, Kozera L, Bréchot C, Hofman P, Dagher G; EU-US Expert Group on cost recovery in biobanks.

    Sci Transl Med. 2014 Nov 5;6(261):261fs45

    PMID: 25378642.

  • Reply: Mutations in the CHCHD10 gene are a common cause of familial amyotrophic lateral sclerosis

    Bannwarth S, Ait-El-Mkadem S, Chaussenot A, Genin EC, Lacas-Gervais S, Fragaki K, Berg-Alonso L, Kageyama Y, Serre V, Moore D, Verschueren A, Rouzier C, Le Ber I, Augé G, Cochaud C, Lespinasse F, N'Guyen K, de Septenville A, Brice A, Yu-Wai-Man P, Sesaki H, Pouget J, Paquis-Flucklinger V.

    2014 Dec;137(Pt 12):e312.

    PMID: 25261971

  • Diverse matrix metalloproteinase functions regulate cancer amoeboid migration.

    Orgaz JL, Pandya P, Dalmeida R, Karagiannis P, Sanchez-Laorden B, Viros A, Albrengues J, Nestle FO, Ridley AJ, Gaggioli C, Marais R, Karagiannis SN, Sanz-Moreno V.

    Nat Commun. 2014 Jun 25;5:4255. 

    PMID: 24963846
  • In vivo imaging of Nematostella vectensis embryogenesis and late development using fluorescent probes

    DuBuc TQ, Dattoli AA, Babonis LS, Salinas-Saavedra M, Röttinger E, Martindale MQ, Postma M.

    BMC Cell Biol. 2014 Nov 30;15:44.

    PMID: 25433655

  • A set of genetically diverged Saccharomyces cerevisiae strains with markerless deletions of multiple auxotrophic genes

    Louvel H, Gillet-Markowska A, Liti G, Fischer G.

    Yeast. 2014 Mar;31(3):91-101. doi: 10.1002/yea.2991.

    PMID: 24288298

  • A high-definition view of functional genetic variation from natural yeast genomes

    Bergström A, Simpson JT, Salinas F, Barré B, Parts L, Zia A, Nguyen Ba AN, Moses AM, Louis EJ, Mustonen V, Warringer J, Durbin R, Liti G.

    Mol Biol Evol. 2014 Apr;31(4):872-88. doi: 10.1093/molbev/msu037

    PMID: 24425782

  • Kinetochore assembly and heterochromatin formation occur autonomously in Schizosaccharomyces pombe

    Brown WR, Thomas G, Lee NC, Blythe M, Liti G, Warringer J, Loose MW.

    Proc Natl Acad Sci U S A. 2014 Feb 4;111(5):1903-8. doi: 10.1073/pnas.1216934111.

    PMID: 2444988

  • Mapping genetic variants underlying differences in the central nitrogen metabolism in fermenter yeasts

    Jara M, Cubillos FA, García V, Salinas F, Aguilera O, Liti G, Martínez C.

    PLoS One. 2014 Jan 21;9(1):e86533. doi: 10.1371/journal.pone.0086533.

    PMID: 24466135

  • Phenotypic characterisation of Saccharomyces spp. yeast for tolerance to stresses encountered during fermentation of lignocellulosic residues to produce bioethanol

    Wimalasena TT, Greetham D, Marvin ME, Liti G, Chandelia Y, Hart A, Louis EJ, Phister TG, Tucker GA, Smart KA.

    Microb Cell Fact. 2014 Mar 27;13(1):47. doi: 10.1186/1475-2859-13-47.

    PMID: 24670111

  • Filling annotation gaps in yeast genomes using genome-wide contact maps

    Marie-Nelly H, Marbouty M, Cournac A, Liti G, Fischer G, Zimmer C, Koszul R.

    Bioinformatics. 2014 Aug 1;30(15):2105-13. doi: 10.1093/bioinformatics/btu162.

    PMID: 24711652

  • Standing genetic variation drives repeatable experimental evolution in outcrossing populations of Saccharomyces cerevisiae

    Burke MK, Liti G, Long AD.

    Mol Biol Evol. 2014 Dec;31(12):3228-39. doi: 10.1093/molbev/msu256.

    PMID: 25172959

  • High-quality genome (re)assembly using chromosomal contact data

    Marie-Nelly H, Marbouty M, Cournac A, Flot JF, Liti G, Parodi DP, Syan S, Guillén N, Margeot A, Zimmer C, Koszul R.

    Nat Commun. 2014 Dec 17;5:5695. doi: 10.1038/ncomms6695.

    PMID: 25517223

  • LIF mediates proinvasive activation of stromal fibroblasts in cancer.

    Albrengues J, Bourget I, Pons C, Butet V, Hofman P, Tartare-Deckert S, Feral CC, Meneguzzi G, Gaggioli C.

    Cell Rep. 2014 Jun 12;7(5):1664-1678. 

    PMID: 24857661
  • A computational approach towards a gene regulatory network for the developing Nematostella vectensis gut

    Botman D, Röttinger E, Martindale MQ, de Jong J, Kaandorp JA.

    PLoS One. 2014 Jul 30;9(7):e103341.

    PMID: 25076223

  • Evidence for G-quadruplex in the promoter of vegfr-2 and its targeting to inhibit tumor angiogenesis.

    Salvati E, Zizza P, Rizzo A, Iachettini S, Cingolani C, D'Angelo C, Porru M, Randazzo A, Pagano B, Novellino E, Pisanu ME, Stoppacciaro A, Spinella F, Bagnato A, Gilson E, Leonetti C, Biroccio A.

    Nucleic Acids Res., 2014, Mar;42(5):2945-57

    PMID: 24335081

  • The Wilms' tumour suppressor Wt1 is a major regulator of tumour angiogenesis and progression.

    Wagner KD, Cherfils-Vicini J, Hosen N, Hohenstein P, Gilson E, Hastie ND, Michiels JF, Wagner N

    Nat Commun., 2014, Dec16;5:5852

    PMID: 25510679

  • Carcinoma-associated fibroblasts in cancer: the great escape.

    Albrengues J, Meneguzzi G, Gaggioli C.

    Med Sci (Paris). 2014 Apr;30(4):391-7.  Review. French.

    PMID: 24801033
  • Biology of Cancer and Aging: A Complex Association With Cellular Senescence.

    Falandry C, Bonnefoy M, Freyer G, Gilson E.

    Clin. Oncol., 2014, Aug20;32(24):2604-10

    PMID: 25071126

  • Shading the TRF2 recruiting function: a new horizon in drug development.

    Di Maro S, Zizza P, Salvati E, De Luca V, Capasso C, Fotticchia I, Pagano B, Marinelli L, Gilson E, Novellino E, Cosconati S, Biroccio A.

    J Am Chem Soc. 2014 Dec 3;136(48):16708-11

    PMID: 25393214

  • Length-dependent processing of telomeres in the absence of telomerase.

    Fallet E, Jolivet P, Soudet J, Lisby M, Gilson E, Teixeira MT.

    Nucleic Acids Res., 2014, Apr;42(6):3648-65

    PMID: 24393774

  • The Telomeric Protein TRF2 Regulates Angiogenesis by Binding and Activating the PDGFRβ Promoter.

    El Maï M, Wagner KD, Michiels JF, Ambrosetti D, Borderie A, Destree S, Renault V, Djerbi N, Giraud-Panis MJ, Gilson E*, Wagner N.

    Cell Rep., 2014, Nov6;9(3):1047-60

    PMID: 25437559

  • Transcriptional outcome of telomere signalling.

    Ye J, Renault VM, Jamet K, Gilson E.

    Nat. Rev. Genet., 2014, Jul;15(7):491-503

    PMID: 24913665

  • A novel pathway links telomeres to NK-cell activity: Implications for immunotherapy.

    Cherfils-Vicini J, Zizza P, Gilson E, Biroccio A.

    Oncoimmunology, 2014, Jan 1;3(1):e27358

    PMID: 24701373

  • Functional polymorphisms in the regulatory regions of the VNN1 gene are associated with susceptibility to inflammatory bowel diseases

    Gensollen T, Bourges C, Rihet P, Rostan A, Millet V, Noguchi T, Bourdon V, Sobol H, Dubuquoy L, Bertin B, Fumery M, Desreumaux P, Colombel JF, Chamaillard M, Hebuterne X, Hofman P, Naquet P, Galland F.

    Inflamm Bowel Dis. 2013 Oct;19(11):2315-25.

    PMID: 23949622

  • Ex-situ Macro Photography of Marine Life

    Ormestad M., Amiel A., Röttinger E

    In: Imaging Marine Life: Modern Imaging techniques in Marine Biology.

    Editor: Emmanuel G. Reynaud. Wiley VCH / Weinheim, 2013

    DOI: 10.1002/9783527675418.ch9

  • Microinjection of mRNA or morpholinos for reverse genetic analysis in the starlet sea anemone, Nematostella vectensis

    Layden MJ, Röttinger E, Wolenski FS, Gilmore TD, Martindale MQ.

    Nat Protoc. 2013 May;8(5):924-34.

    PMID: 23579781

  • The specificity and flexibility of L1 reverse transcription priming at imperfect T-tracts.

    Monot C, Kuciak M, Viollet S, Mir AA, Gabus C, Darlix JL, Cristofari G.

    PLoS Genet. 2013 May;9(5):e1003499.

    PMID: 23675310
  • High-resolution mapping of complex traits with a four-parent advanced intercross yeast population

    Cubillos FA, Parts L, Salinas F, Bergström A, Scovacricchi E, Zia A, Illingworth CJ, Mustonen V, Ibstedt S, Warringer J, Louis EJ, Durbin R, Liti G.

    Genetics. 2013 Nov;195(3):1141-55. doi: 10.1534/genetics.113.155515.

    PMID: 24037264

  • ICY 2012 highlights

    Abbas C, Kurtzman C, Liti G.

    Yeast. 2013 Aug;30(8):293-4. doi: 10.1002/yea.2966.

    PMID: 23922150

  • The accreditation of a surgical pathology and somatic genetic laboratory (LPCE, CHU of Nice) according to the ISO 15189 norm: Sharing of experience

    Washetine K, Long E, Hofman V, Lassalle S, Ilie M, Lespinet V, Bonnetaud C,  Bordone O, Gavric-Tanga V, Selva E, Reverso-Meinietti J, Sadoulet D, Lacour L, Bille Y, Lavagna R, Grier P, Zahaf K, Mari M, Hofman P

    Ann Pathol. 2013 Dec;33(6):386-97.

    PMID: 24331720

  • BRAF EQA Group. Improvement of the quality of BRAF testing in melanomas with nationwide external quality assessment, for the BRAF EQA group

    Emile JF, Tisserand J, Bergougnoux L, Nowak F, Faucher G, Surel S, Lamy A, Lecorre D, Helias-Rodzewicz Z, Hofman P, Sabourin JC, Laurent-Puig P.

    BMC Cancer. 2013 Oct 11;13:472

    PMID: 24004837

  • Acute kidney injury following crizotinib administration for non-small-cell lung carcinoma

    Gastaud L, Ambrosetti D, Otto J, Marquette CH, Coutts M, Hofman P, Esnault V, Favre G.

    Lung Cancer. 2013 Nov;82(2):362-4.

    PMID: 24001942

  • Signalphagy: scheduled signal termination by macroautophagy

    Belaid A, Ndiaye PD, Klionsky DJ, Hofman P, Mograbi B.

    Autophagy. 2013 Oct;9(10):1629-30

    PMID: 24004837

  • BRIF working group. Quantifying the use of bioresources for promoting their sharing in scientific research

    Mabile L, Dalgleish R, Thorisson GA, Deschênes M, Hewitt R, Carpenter J, Bravo E, Filocamo M, Gourraud PA, Harris JR, Hofman P, Kauffmann F, Muñoz-Fernàndez MA, Pasterk M, Cambon-Thomsen A

    Gigascience. 2013 May 1;2(1):7

    PMID: 23634721

  • Telomerase is required for zebrafish lifespan.

    Henriques CM, Carneiro MC, Tenente IM, Jacinto A, Ferreira MG.

    PLoS genetics. 2013; 9(1):e1003214.

    PMID: 23349637
  • Significance of circulating tumor cell detection using the CellSearch system in patients with locally advanced head and neck squamous cell carcinoma.

    Bozec A, Ilie M, Dassonville O, Long E, Poissonnet G, Santini J, Chamorey E, Ettaiche M, Chauvière D, Peyrade F, Hebert C, Benezery K, Sudaka A, Haudebourg J, Selva E, Hofman P.

    Eur Arch Otorhinolaryngol. 2013 Sep;270(10):2745-9.

    doi: 10.1007/s00405-013-2399-y. Epub 2013 Feb 22.

    PMID: 23430081

  • Two panels of plasma microRNAs as non-invasive biomarkers for prediction of recurrence in resectable NSCLC. PLoS One. 2013;8(1):e54596.

    Sanfiorenzo C*, Ilie MI*, Belaid A, Barlési F, Mouroux J, Marquette CH, Brest P*, Hofman P*.

    doi: 10.1371/journal.pone.0054596. Epub 2013 Jan 16.

    PMID: 23342174


  • RNA-mediated interference and reverse transcription control the persistence of RNA viruses in the insect model Drosophila.

    Goic B, Vodovar N, Mondotte JA, Monot C, Frangeul L, Blanc H, Gausson V, Vera-Otarola J, Cristofari G, Saleh MC.

    Nat Immunol. 2013 Apr;14(4):396-403.

    PMID: 23435119
  • Sowing the seeds of cancer: telomeres and age-associated tumorigenesis.

    Pereira B, Ferreira MG.

    Current opinion in oncology. 2013; 25(1):93-8.

    PMID: 23211840
  • Significance of circulating tumor cell detection using the CellSearch system in patients with locally advanced head and neck squamous cell carcinoma

    Bozec A, Ilie M, Dassonville O, Long E, Poissonnet G, Santini J, Chamorey E, Ettaiche M, Chauvière D, Peyrade F, Hebert C, Benezery K, Sudaka A, Haudebourg J, Selva E, Hofman P

    Eur Arch Otorhinolaryngol. 2013 Sep;270(10):2745-9.

    PMID: 23430081.

  • Noisy silent polymorphisms

    Korzeniewski S, Hofman P, Brest P

    Med Sci (Paris). 2013 Feb;29(2):124-6

    PMID: 23452592

  • Accreditation of the activity of molecular pathology according to ISO 15189: key steps to follow and the main potential pitfalls

    Long E, Hofman V, Ilie M, Washetine K, Lespinet V, Bonnetaud C, Bordone O, Gavric-Tanga V, Gaziello MC, Lassalle S, Selva E, Zahaf K, Lamy A, Sabourin JC, Hofman P

    Ann Pathol. 2013 Feb;33(1):12-23

    PMID: 23472892

  • Setting up a department of molecular pathology in oncology in a pathology laboratory (LPCE, CHU de Nice).

    Long E, Hofman V, Ilie M, Lespinet V, Bonnetaud C, Bordone O, Gavric-Tanga V, Washetine K, Gaziello MC, Mauro V, Lassalle S, Selva E, Zahaf K, Santini J, Castillo L, Lacour JP, Vénissac N, Mouroux J, Otto J, Poudenx M, Marquette CH, Sabourin JC, Hofman P

    Ann Pathol. 2013 Feb;33(1):24-37

    PMID: 23472893

  • Comparison of transcriptomic signature of post-Chernobyl and postradiotherapy thyroid tumors.

    Ory C, Ugolin N, Hofman P, Schlumberger M, Likhtarev IA, Chevillard S

    Thyroid. 2013 Nov;23(11):1390-400

    PMID: 23521174

  • Specificities of lung adenocarcinoma in women who have never smoked

    Mazières J, Rouquette I, Lepage B, Milia J, Brouchet L, Guibert N, Beau-Faller M, Validire P, Hofman P, Fouret P.

    J Thorac Oncol. 2013 Jul;8(7):923-9

    PMID: 23608817

  • Autophagy plays a critical role in the degradation of active RHOA, the control of cell cytokinesis, and genomic stability.

    Belaid A, Cerezo M, Chargui A, Corcelle-Termeau E, Pedeutour F, Giuliano S,  Ilie M, Rubera I, Tauc M, Barale S, Bertolotto C, Brest P, Vouret-Craviari V, Klionsky DJ, Carle GF, Hofman P, Mograbi B.

    Cancer Res. 2013 Jul 15;73(14):4311-22

    PMID: 23704209

  • Role of the surgical pathologist for tissue management in oncology

    Long É, Ilie M, Hofman V, Lassalle S, Butori C, AlsubaieS, Hofman P

    Bull Cancer. 2013 Sep;100(9):837-45

    PMID: 23985751

  • Major clinical response to a BRAF inhibitor in a patient with a BRAF L597R-mutated melanoma

    Bahadoran P, Allegra M, Le Duff F, Long-Mira E, Hofman P, Giacchero D, Passeron T, Lacour JP, Ballotti R.

    J Clin Oncol. 2013 Jul 1;31(19):e324-6

    PMID: 23715574

  • Usefulness of immunocytochemistry for the detection of the BRAF(V600E) mutation in circulating tumor cells from metastatic melanoma patients.

    Hofman V, Ilie M, Long-Mira E, Giacchero D, Butori C, Dadone B, Selva E, Tanga V, Passeron T, Poissonnet G, Emile JF, Lacour JP, Bahadoran P, Hofman P.

    J Invest Dermatol.  2013 May;133(5):1378-81.

    doi: 10.1038/jid.2012.485. Epub 2013 Jan 10.

    PMID: 23303445

  • Role of CFTR in oxidative stress and suicidal death of renal cells during cisplatin-induced nephrotoxicity.

    Rubera I, Duranton C, Melis N, Cougnon M, Mograbi B, Tauc M.

    Cell Death Dis. 2013 Oct 3;4: e817. doi: 10.1038/cddis.2013.355.

    PMID: 24091660

  • Telomere protection and TRF2 expression are enhanced by the canonical Wnt signalling pathway

    Diala I, Wagner N, Magdinier F, Shkreli M, Sirakov M, Bauwens S, Schluth-Bolard C, Simonet T, Renault VM, Ye J, Djerbi A, Pineau P, Choi J, Artandi S, Dejean A, Plateroti M, Gilson E.

    EMBO Rep. 2013 Apr;14(4):356-63

    PMID: 23429341

  • High quality de novo sequencing and assembly of the Saccharomyces arboricolus genome

    Liti G, Nguyen Ba AN, Blythe M, Müller CA, Bergström A, Cubillos FA, Dafhnis-Calas F, Khoshraftar S, Malla S, Mehta N, Siow CC, Warringer J, Moses AM, Louis EJ, Nieduszynski CA.

    BMC Genomics. 2013 Jan 31;14:69. doi: 10.1186/1471-2164-14-69.

    PMID: 23368932

  • Recurrent rearrangement during adaptive evolution in an interspecific yeast hybrid suggests a model for rapid introgression

    Dunn B, Paulish T, Stanbery A, Piotrowski J, Koniges G, Kroll E, Louis EJ, Liti G, Sherlock G, Rosenzweig F.

    PLoS Genet. 2013 Mar;9(3):e1003366. doi: 10.1371/journal.pgen.1003366.

    PMID: 23555283

  • Ancient evolutionary trade-offs between yeast ploidy states

    Zörgö E, Chwialkowska K, Gjuvsland AB, Garré E, Sunnerhagen P, Liti G, Blomberg A, Omholt SW, Warringer J.

    PLoS Genet. 2013 Mar;9(3):e1003388. doi: 10.1371/journal.pgen.1003388.

    PMID: 23555297

  • Inferring genome-wide recombination landscapes from advanced intercross lines: application to yeast crosses

    Illingworth CJ, Parts L, Bergström A, Liti G, Mustonen V.

    PLoS One. 2013 May 2;8(5):e62266. doi: 10.1371/journal.pone.0062266.

    PMID: 23658715

  • CD98hc (SLC3A2) regulation of skin homeostasis wanes with age

    Boulter E, Estrach S, Errante A, Pons C, Cailleteau L, Tissot F, Meneguzzi G, Féral CC.

    J Exp Med. 2013 Jan 14;210(1):173-90. doi: 10.1084/jem.20121651. Epub 2013 Jan 7.


  • In papillary thyroid carcinoma, TIMP-1 expression correlates with BRAF (V600E) mutation status and together with hypoxia-related proteins predicts aggressive behavior

    Ilie MI, Lassalle S, Long-Mira E, Hofman V, Zangari J, Bénaim G, Bozec A, Guevara N, Haudebourg J, Birtwisle-Peyrottes I, Santini J, Brest P, Hofman P.

    Virchows Arch. 2013 Sep;463(3):437-44

    PMID: 23893334

  • Response of CAIX and CAXII to in vitro re-oxygenation and clinical significance of the combined expression in NSCLC patients

    Ilie M, Hofman V, Zangari J, Chiche J, Mouroux J, Mazure NM, Pouysségur J, Brest P, Hofman P.

    Lung Cancer.  2013 Oct;82(1):16-23.

    PMID: 23910904

  • Measuring the contribution of tumor biobanks to research in oncology: surrogate indicators and bibliographic output

    Hofman V, Ilie M, Long E, Washetine K, Chabannon C, Figarella-Branger D, Clément B, Mabile L, Cambon-Thomsen A, Boucher P, Dagher G, Hewitt R, Parodi B, Hofman P.

    Biopreserv Biobank. 2013 Aug;11(4):235-44

    PMID: 24845591

  • Structure of active dimeric human telomerase.

    Sauerwald A, Sandin S, Cristofari G, Scheres SH, Lingner J, Rhodes D.

    Nat Struct Mol Biol. 2013 Apr;20(4):454-60.

    PMID: 23474713

  • EBV infection is common in gingival epithelial cells of the periodontium and worsens during chronic periodontitis.

    Vincent-Bugnas S, Vitale S, Mouline CC, Khaali W, Charbit Y, Mahler P, Prêcheur I, Hofman P, Maryanski JL, Doglio A

    PLoS One. 2013 Dec 19;8(12):e80336

    PMID: 24367478

  • Telomeric impact of conventional chemotherapy


    Lu Y, Leong W, Guérin O, Gilson E, Ye J.

    Front Med. 2013 Dec;7(4):411-7

    PMID: 24155095

  • Effect of Rap1 binding on DNA distortion and potassium permanganate hypersensitivity.

    Le Bihan YV, Matot B, Pietrement O, Giraud-Panis MJ, Gasparini S, Le Cam E, Gilson E, Sclavi B, Miron S, Le Du MH.

    Acta Crystallogr D Biol Crystallogr. 2013 Mar;69(Pt 3):409-19

    PMID: 23519416


  • Bladder-sphincter disorders associated with Wolfram syndrome

    Ribière C, Kaboré FA, Chaussenot A, Paquis-Flucklinger V, Lenne-Aurier K, Gaillet S, Boissier R, Karsenty G.

    Prog Urol. 2013 Jun;23(8):519-23.

    PMID: 23725582

  • EURO-WABB: an EU rare diseases registry for Wolfram syndrome, Alström syndrome and Bardet-Biedl syndrome

    Farmer A, Aymé S, de Heredia ML, Maffei P, McCafferty S, Młynarski W, Nunes V, Parkinson K, Paquis-Flucklinger V, Rohayem J, Sinnott R, Tillmann V, Tranebjaerg L, Barrett TG.

    BMC Pediatr. 2013 Aug 27;13:130.

    PMID: 23981649 

  • One identity or more for telomeres?

    Giraud-Panis MJ, Pisano S, Benarroch-Popivker D, Pei B, Le Du MH, Gilson E (*).

    Front Oncol. 2013;3:48

    PMID: 23509004

  • Prevalence of rare mitochondrial DNA mutations in mitochondrial disorders

    Bannwarth S, Procaccio V, Lebre AS, Jardel C, Chaussenot A, Hoarau C, Maoulida H, Charrier N, Gai X, Xie HM, Ferre M, Fragaki K, Hardy G, Mousson de Camaret B, Marlin S, Dhaenens CM, Slama A, Rocher C, Paul Bonnefont J, Rötig A, Aoutil N, Gilleron M, Desquiret-Dumas V, Reynier P, Ceresuela J, Jonard L, Devos A, Espil-Taris C, Martinez D, Gaignard P, Le Quan Sang KH, Amati-Bonneau P, Falk MJ, Florentz C, Chabrol B, Durand-Zaleski I, Paquis-Flucklinger V.

    J Med Genet. 2013 Oct;50(10):704-14.

    PMID: 23847141 

  • Improvement of the quality of BRAF testing in melanomas with nationwide external quality assessment, for the BRAF EQA group.

    Emile JF, Tisserand J, Bergougnoux L, Nowak F, Faucher G, Surel S, Lamy A, Lecorre D, Helias-Rodzewicz Z, Hofman P, Sabourin JC, Laurent-Puig P; BRAF EQA Group.

    BMC Cancer. 2013 Oct 11;13:472. doi: 10.1186/1471-2407-13-472.

    PMID: 24119386
  • A renal metanephric adenoma showing both a 2p16e24 deletion and BRAF V600E mutation: a synergistic role for a tumor suppressor gene on chromosome 2p and BRAF activation?

    Dadone B, Ambrosetti D, Carpentier X, Duranton-Tanneur V, Burel-Vandenbos F, Amiel J, Pedeutour F.

    Cancer Genet. 2013 Sep-Oct;206(9-10):347-52.

    PMID: 24432405
  • Performance and cost efficiency of KRAS mutation testing for metastatic colorectal cancer in routine diagnosis: the MOKAECM study, a nationwide experience.

    Blons H, Rouleau E, Charrier N, Chatellier G, Côté JF, Pages JC, de Fraipont F, Boyer JC, Merlio JP, Morel A, Gorisse MC, de Cremoux P, Leroy K, Milano G, Ouafik L, Merlin JL, Le Corre D, Aucouturier P, Sabourin JC, Nowak F, Frebourg T, Emile JF, Durand-Zaleski I, Laurent-Puig P; MOKAECM Collaborative Group.

    PLoS One. 2013 Jul 25;8(7):e68945. doi: 10.1371/journal.pone.0068945. Print 2013.

    PMID: 23935912
  • Comparative cost analysis of molecular biology methods in the diagnosis of sarcomas.

    Baffert S, Italiano A, Pierron G, Traoré MA, Rapp J, Escande F, Ghnassia JP, Terrier P, Voegeli AC, Ranchere-Vince D, Coindre JM, Pedeutour F.

    Bull Cancer. 2013 Oct;100(10):963-71. doi: 10.1684/bdc.2013.1822. French.

    PMID: 24095719
  • Telomere protection and TRF2 expression are enhanced by the the canonical Wnt signalling pathway.

    Diala I, Wagner N, Magdinier F, Shkreli M, Sirakov M, Bauwens S, Schluth-Bolard C, Simonet T, Renault VM, Ye J, Djerbi A, Pineau P, Choi J, Artandi S, Dejean A, Plateroti M, Gilson E.

    EMBO Rep. 2013 Apr;14(4):356-63

    PMID: 23429341

  • EGFR, KRAS, BRAF, and HER-2 molecular status in brain metastases from 77 NSCLC patients.

    Villalva C, Duranton-Tanneur V, Guilloteau K, Burel-Vandenbos F, Wager M, Doyen J, Levillain PM, Fontaine D, Blons H, Pedeutour F, Karayan-Tapon L.

    Cancer Med. 2013 Jun;2(3):296-304. doi: 10.1002/cam4.82. Epub 2013 Apr 23.

    PMID: 23930206
  • Conservative multimodal management of a primitive neuroectodermal tumor of the thyroid.

    Natale R, Thariat J, Vedrine PO, Bozec A, Peyrottes I, Marcy PY, Haudebourg J, Pedeutour F, Saâda E, Thyss A.

    Rare Tumors. 2013 May 29;5(2):75-8. doi: 10.4081/rt.2013.e20. Print 2013 Apr 15.

    PMID: 23888220
  • Identification of PPAP2B as a novel recurrent translocation partner gene of HMGA2 in lipomas.

    Bianchini L, Birtwisle L, Saâda E, Bazin A, Long E, Roussel JF, Michiels JF, Forest F, Dani C, Myklebost O, Birtwisle-Peyrottes I, Pedeutour F.

    Genes Chromosomes Cancer. 2013 Jun;52(6):580-90. doi: 10.1002/gcc.22055. Epub 2013 Mar 18.

    PMID: 23508853
  • Immunohistological features in adenomatoid odontogenic tumor: review of the literature and first expression and mutational analysis of β-catenin in this unusual lesion of the jaws.

    Harnet JC, Pedeutour F, Raybaud H, Ambrosetti D, Fabas T, Lombardi T.

    J Oral Maxillofac Surg. 2013 Apr;71(4):706-13. doi: 10.1016/j.joms.2012.10.006. Epub 2012 Dec 20. Review.

    PMID: 23265580
  • EGFR mutation status in brain metastases of non-small cell lung carcinoma.

    Burel-Vandenbos F, Ambrosetti D, Coutts M, Pedeutour F.

    J Neurooncol. 2013 Jan;111(1):1-10. doi: 10.1007/s11060-012-0990-5. Epub 2012 Oct 20. Review.

    PMID: 23086434
  • Comprehensive genome characterization of solitary fibrous tumors using high-resolution array-based comparative genomic hybridization.

    Bertucci F, Bouvier-Labit C, Finetti P, Adélaïde J, Metellus P, Mokhtari K, Decouvelaere AV, Miquel C, Jouvet A, Figarella-Branger D, Pedeutour F, Chaffanet M, Birnbaum D.

    Genes Chromosomes Cancer. 2013 Feb;52(2):156-64. doi: 10.1002/gcc.22015. Epub 2012 Oct 17.

    PMID: 23073997
  • Analysis of collective invasion of carcinoma cells in a 3D organotypic model.

    Albrengues J, Meneguzzi G, Gaggioli C.

    Methods Mol Biol. 2013;961:243-52. 

    PMID: 23325648
  • Relative frequencies of inherited retinal dystrophies and optic neuropathies in Southern France: assessment of 21-year data management

    Bocquet B, Lacroux A, Surget MO, Baudoin C, Marquette V, Manes G, Hebrard M, Sénéchal A, Delettre C, Roux AF, Claustres M, Dhaenens CM, Rozet JM, Perrault I, Bonnefont JP, Kaplan J, Dollfus H, Amati-Bonneau P, Bonneau D, Reynier P, Audo I, Zeitz C, Sahel JA, Paquis-Flucklinger V, Calvas P, Arveiler B, Kohl S, Wissinger B, Blanchet C, Meunier I, Hamel CP.

    Ophthalmic Epidemiol. 2013;20(1):13-25.

    PMID: 23350551

  • Refractory epilepsy and mitochondrial dysfunction due to GM3 synthase deficiency

    Fragaki K, Ait-El-Mkadem S, Chaussenot A, Gire C, Mengual R, Bonesso L, Bénéteau M, Ricci JE, Desquiret-Dumas V, Procaccio V, Rötig A, Paquis-Flucklinger V.

    Eur J Hum Genet. 2013 May;21(5):528-34.

    PMID: 22990144

  • Are aging biomarkers clinically relevant in oncogeriatrics?

    Falandry C, Gilson E, Rudolph KL.

    Crit Rev Oncol Hematol. 2013 Mar;85(3):257-65

    PMID: 22948097

  • Super-telomeres in transformed human fibroblasts

    Chiodi I, Belgiovine C, Zongaro S, Ricotti R, Horard B, Lossani A, Focher F, Gilson E, Giulotto E, Mondello C.

    Biochim Biophys Acta. 2013 Aug;1833(8):1885-93

    PMID: 23570868


  • TRF2 inhibits a cell-extrinsic pathway through which natural killer cells eliminate cancer cells.

    Biroccio A, Cherfils-Vicini J, Augereau A, Pinte S, Bauwens S, Ye J, Simonet T, Horard B, Jamet K, Cervera L, Mendez-Bermudez A, Poncet D, Grataroli R, de Rodenbeeke CT, Salvati E, Rizzo A, Zizza P, Ricoul M, Cognet C, Kuilman T, Duret H, Lépinasse F, Marvel J, Verhoeyen E, Cosset FL, Peeper D, Smyth MJ, Londoño-Vallejo A, Sabatier L, Picco V, Pages G, Scoazec JY, Stoppacciaro A, Leonetti C, Vivier E, Gilson E

    Nat Cell Biol. 2013 Jul;15(7):818-28

    PMID: 23792691

  • Acacetin and chrysin, two polyphenolic compounds, alleviate telomeric position effect in human cells

     Boussouar A, Barette C, Nadon R, Saint-Léger A, Broucqsault N, Ottaviani A, Firozhoussen A, Lu Y, Lafanechère L, Gilson E. Magdinier F , Ye J.

    Mol Ther Nucleic Acids. 2013 Aug 20;2:e116

    PMID: 23962900

  • Apparent ploidy effects on silencing are post-transcriptional at HML and telomeres in Saccharomyces cerevisiae

    McLaughlan JM, Liti G, Sharp S, Maslowska A, Louis EJ.

    PLoS One. 2012;7(7):e39044. doi: 10.1371/journal.pone.0039044.

    PMID: 22792162

  • HTLV-1 positive and negative T cells cloned from infected individuals display telomerase and telomere genes deregulation that predominate in activated but untransformed CD4+ T cells.

    Zane L, Sibon D, Capraro V, Galia P, Karam M, Delfau-Larue MH, Gilson E, Gessain A, Gout O, Hermine O, Mortreux F, Wattel E.

    Int J Cancer. 2012 Aug 15;131(4):821-33.

    PMID: 21717459

  • RPA facilitates telomerase activity at chromosome ends in budding and fission yeasts.

    Luciano P, Coulon S, Faure V, Corda Y, Bos J, Brill SJ, Gilson E, Simon MN, Géli V.  (2012)

    EMBO J. 2012 Apr 18;31(8):2034-46

    PMID: 22354040

  • A snapshot of histone modifications within transposable elements in Drosophila wild type strains.

     Rebollo R, Horard B, Begeot F, Delattre M, Gilson E, Vieira C.

    PLoS One. 2012;7(9):e44253

    PMID: 22962605


  • Subversion of autophagy in adherent invasive Escherichia coli-infected neutrophils induces inflammation and cell death. PLoS One. 2012;7(12):e51727.

    Chargui A, Cesaro A, Mimouna S, Fareh M, Brest P, Naquet P, Darfeuille-Michaud A, Hébuterne X, Mograbi B, Vouret-Craviari V, Hofman P.

    doi: 10.1371/journal.pone.0051727. Epub 2012 Dec 14.

    PMID: 23272151

  • TRF2 controls telomeric nucleosome organization in a cell cycle phase-dependent manner

    Galati A, Magdinier F, Colasanti V, Bauwens S, Pinte S, Ricordy R, Giraud-Panis MJ, Pusch MC, Savino M, Cacchione S, Gilson E. (*).

    PLoS One. 2012;7(4):e34386

    PMID: 22536324

  • Comprehensive DNA methylation profiling of human repetitive DNA elements using an MeDIP-on-RepArray assay

    Gilson E, Horard B.

    Methods Mol Biol. 2012;859:267-91.

    PMID: 22367878

  • Evolutionary crossroads in developmental biology: hemichordates

    Röttinger E, Lowe CJ.

    Development. 2012 Jul;139(14):2463-75. doi: 10.1242/dev.066712.

    PMID: 22736243

  • RPA facilitates telomerase activity at chromosome ends in budding and fission yeasts

    Luciano P, Coulon S, Faure V, Corda Y, Bos J, Brill SJ, Gilson E, Simon MN, Géli V

    EMBO J. 2012 Apr 18;31(8):2034-46.

    PMID: 22354040

  • The N-terminal domains of TRF1 and TRF2 regulate their ability to condense telomeric DNA.

    Poulet A, Pisano S, Faivre-Moskalenko C, Pei B, Tauran Y, Haftek-Terreau Z, Brunet F, Le Bihan YV, Ledu MH, Montel F, Hugo N, Amiard S, Argoul F, Chaboud A, Gilson E(*), Giraud-Panis MJ.

    Nucleic Acids Res. 2012 Mar;40(6):2566-76.

    PMID: 22139926


  • Self-renewal gene tracking to identify tumour-initiating cells associated with metastatic potential.

    Darini CY, Pisani DF, Hofman P, Pedeutour F, Sudaka I, Chomienne C, Dani C, Ladoux A.

    Oncogene. 2012 May 10;31(19):2438-49. doi: 10.1038/onc.2011.421. Epub 2011 Sep 19.

    PMID: 21927026
  • A comparative and integrative approach identifies ATPase family, AAA domain containing 2 as a likely driver of cell proliferation in lung adenocarcinoma.

    Fouret R, Laffaire J, Hofman P, Beau-Faller M, Mazieres J, Validire P, Girard P, Camilleri-Bröet S, Vaylet F, Leroy-Ladurie F, Soria JC, Fouret P.

    Clin Cancer Res. 2012 Oct 15;18(20):5606-16.

    doi: 10.1158/1078-0432.CCR-12-0505.  Epub 2012 Aug 22.

    PMID: 22914773

  • Life history shapes trait heredity by accumulation of loss-of-function alleles in yeast

    Zörgö E, Gjuvsland A, Cubillos FA, Louis EJ, Liti G, Blomberg A, Omholt SW, Warringer J.

    Mol Biol Evol. 2012 Jul;29(7):1781-9. doi: 10.1093/molbev/mss019.

    PMID: 22319169

  • Rearrangement of HMGA2 in a case of infantile lipoblastoma without PLAG1 alteration.

    Pedeutour F, Deville A, Steyaert H, Ranchere-Vince D, Ambrosetti D, Sirvent N.

    Pediatr Blood Cancer. 2012 May;58(5):798-800. doi: 10.1002/pbc.23335. Epub 2012 Jan 6.

    PMID: 22223189
  • The genetic basis of natural variation in oenological traits in Saccharomyces cerevisiae

    Salinas F, Cubillos FA, Soto D, Garcia V, Bergström A, Warringer J, Ganga MA, Louis EJ, Liti G, Martinez C.

    PLoS One. 2012;7(11):e49640. doi: 10.1371/journal.pone.0049640.

    PMID: 23185390

  • 'New' yeasts for a new Yeast

    Armstrong J, Davis D, Liti G, Oliver S.

    Yeast. 2012 Oct;29(10):407. doi: 10.1002/yea.2923.

    PMID: 23065797

  • First description of inhibition of let-7 microRNA expression and HMGA2 overexpression in a case of deep-seated diffuse lipomatosis.

    Saâda E, Bianchini L, Mouroux J, Dupré F, Butori C, Birtwisle-Peyrottes I, Padovani B, Yver M, Ferrari C, Pedeutour F.

    Histopathology. 2012 Sep;61(3):519-22. doi: 10.1111/j.1365-2559.2012.04266.x. Epub 2012 May 29. No abstract available.

    PMID: 22642449
  • Quantifying selection acting on a complex trait using allele frequency time series data

    Illingworth CJ, Parts L, Schiffels S, Liti G, Mustonen V.

    Mol Biol Evol. 2012 Apr;29(4):1187-97. doi: 10.1093/molbev/msr289.

    PMID: 22114362

  • Advances in quantitative trait analysis in yeast

    Liti G, Louis EJ.

    PLoS Genet. 2012;8(8):e1002912. doi: 10.1371/journal.pgen.1002912.

    PMID: 22916041

  • Surprisingly diverged populations of Saccharomyces cerevisiae in natural environments remote from human activity

    Wang QM, Liu WQ, Liti G, Wang SA, Bai FY.

    Mol Ecol. 2012 Nov;21(22):5404-17. doi: 10.1111/j.1365-294X.2012.05732.x.

    PMID: 22913817

  • SMARCB1/INI1 inactivation in renal medullary carcinoma.

    Calderaro J, Moroch J, Pierron G, Pedeutour F, Grison C, Maillé P, Soyeux P, de la Taille A, Couturier J, Vieillefond A, Rousselet MC, Delattre O, Allory Y.

    Histopathology. 2012 Sep;61(3):428-35. doi: 10.1111/j.1365-2559.2012.04228.x. Epub 2012 Jun 11.

    PMID: 22686875
  • A newly characterized human well-differentiated liposarcoma cell line contains amplifications of the 12q12-21 and 10p11-14 regions.

    Pedeutour F, Maire G, Pierron A, Thomas DM, Garsed DW, Bianchini L, Duranton-Tanneur V, Cortes-Maurel A, Italiano A, Squire JA, Coindre JM.

    Virchows Arch. 2012 Jul;461(1):67-78. doi: 10.1007/s00428-012-1256-5. Epub 2012 Jun 8.

    PMID: 22678079
  • Guidelines for the use and interpretation of assays for monitoring autophagy.

    Klionsky DJ, …, Brest P, …, Hofman P, …, Mograbi B,…et al.

    Autophagy. 2012 Apr;8(4):445-544.

    PMID: 22966490


  • Renal cell carcinoma and a constitutional t(11;22)(q23;q11.2): case report and review of the potential link between the constitutional t(11;22) and cancer.

    Doyen J, Carpentier X, Haudebourg J, Hoch B, Karmous-Benailly H, Ambrosetti D, Fabas T, Amiel J, Lambert JC, Pedeutour F.

    Cancer Genet. 2012 Nov;205(11):603-7. doi: 10.1016/j.cancergen.2012.09.006. Epub 2012 Oct 30.

    PMID: 23117075
  • Predictive clinical outcome of the intratumoral CD66b-positive neutrophil-to-CD8-positive T-cell ratio in patients with resectable nonsmall cell lung cancer.

    Ilie M, Hofman V, Ortholan C, Bonnetaud C, Coëlle C, Mouroux J, Hofman P.

    Cancer. 2012 Mar 15;118(6):1726-37.

    doi: 10.1002/cncr.26456. Epub 2011 Aug 25.

    PMID: 21953630

  • The human MSH5 (MutSHomolog 5) protein localizes to mitochondria and protects the mitochondrial genome from oxidative damage

    Bannwarth S, Figueroa A, Fragaki K, Destroismaisons L, Lacas-Gervais S, Lespinasse F, Vandenbos F, Pradelli LA, Ricci JE, Rötig A, Michiels JF, Vande Velde C, Paquis-Flucklinger V.

    Mitochondrion. 2012 Nov;12(6):654-65.

    PMID: 22917773

  • Epilepsy and mitochondrial diseases: retrospective study on 53 epileptic children

    Caietta E, Cano A, Halbert C, Hugonenq C, Mancini J, Milh M, Lépine A, Villeneuve N, Chaussenot A, Paquis-Flucklinger V, Chabrol B.

    Arch Pediatr. 2012 Aug;19(8):794-802. 

    PMID: 22789745

  • Cataract as a phenotypic marker for a mutation in WFS1, the Wolfram syndrome gene

    Titah SM, Meunier I, Blanchet C, Lopez S, Rondouin G, Lenaers G, Amati-Bonneau P, Reynier P, Paquis-Flucklinger V, Hamel CP.

    Eur J Ophthalmol. 2012 Mar-Apr;22(2):254-8.

    PMID: 21623591

  • HSFY genes and the P4 palindrome in the AZFb interval of the human Y chromosome are not required for spermatocyte maturation

    Kichine E, Rozé V, Di Cristofaro J, Taulier D, Navarro A, Streichemberger E, Decarpentrie F, Metzler-Guillemain C, Lévy N, Chiaroni J, Paquis-Flucklinger V, Fellmann F, Mitchell MJ.

    Hum Reprod. 2012 Feb;27(2):615-24.

    PMID: 22158087

  • The MFN2 gene is responsible for mitochondrial DNA instability and optic atrophy 'plus' phenotype
  • Drug delivery by polymeric nanoparticles induces autophagy in macrophages.

    Eidi H, Joubert O, Némos C, Grandemange S, Mograbi B, Foliguet B, Tournebize J, Maincent P, Le Faou A, Aboukhamis I, Rihn BH.

    Int J Pharm. 2012 Jan 17;422(1-2):495-503. doi: 10.1016/j.ijpharm.2011.11.020. Epub 2011 Nov 22.

    PMID: 22119964

  • CFTR is involved in the fine tuning of intracellular redox status: physiological implications in cystic fibrosis.

    Duranton C, Rubera I, Cougnon M, Melis N, Chargui A, Mograbi B, Tauc M.

    Am J Pathol. 2012 Oct;181(4):1367-77. doi: 10.1016/j.ajpath.2012.06.017. Epub 2012 Jul 28.

    PMID: 22846720

  • Distinct epithelial gene expression phenotypes in childhood respiratory allergy.

    Giovannini-Chami L, Marcet B, Moreilhon C, Chevalier B, Illie MI, Lebrigand K, Robbe-Sermesant K, Bourrier T, Michiels JF, Mari B, Crénesse D, Hofman P, de Blic J, Castillo L, Albertini M, Barbry P.

    Eur Respir J. 2012 May;39(5):1197-205.

    doi: 10.1183/09031936.00070511. Epub 2011 Oct 17.

    PMID: 22005912

  • Annual Conferences of the European, Middle Eastern and African Society for Biopreservation and Biobanking (ESBB): overview of 2011 and preview of 2012.

    Chabannon C, Doran P, Hofman P, Seberg O, Cinotti S, Bledsoe M, Deigner HP,  Koschorreck J, Dagher G, Cooreman A, De Blasio P, Riegman P, Hewitt R.

    Biopreserv Biobank. 2012 Oct;10(5):407-15.

    doi: 10.1089/bio.2012.1052.

    PMID: 24845041

  • Crohn disease-associated Escherichia coli promote gastrointestinal inflammatory disorders by activation of HIF-dependent responses.

    Mimouna S, Gonçalvès D, Barnich N, Darfeuille-Michaud A, Hofman P, Vouret-Craviari V.

    Gut Microbes. 2011 Nov-Dec;2(6):335-46.

    doi: 10.4161/gmic.18771. Epub 2011 Nov 1.

    PMID: 22157238

  • International Congress on Transposable Elements (ICTE) 2012 in Saint Malo and the sea of TE stories.

    Ainouche A, Bétermier M, Chandler M, Cordaux R, Cristofari G, Deragon JM, Lesage P, Panaud O, Quesneville H, Vaury C, Vieira C, Vitte C.

    Mob DNA. 2012 Oct 30;3(1):17. Meeting Report.

    PMID: 23110759
  • The catalytic and the RNA subunits of human telomerase are required to immortalize equid primary fibroblasts.

    Vidale P, Magnani E, Nergadze SG, Santagostino M, Cristofari G, Smirnova A, Mondello C, Giulotto E.

    Chromosoma. 2012 Oct;121(5):475-88.

    PMID: 22797876
  • A single zinc finger optimizes the DNA interactions of the nucleocapsid protein of the yeast retrotransposon Ty3.

    Chaurasiya KR, Geertsema H, Cristofari G, Darlix JL, Williams MC.

    Nucleic Acids Res. 2012 Jan;40(2):751-60.

    PMID: 21917850
  • Expression of a truncated active form of VDAC1 in lung cancer associates with hypoxic cell survival and correlates with progression to chemotherapy resistance.

    Brahimi-Horn MC, Ben-Hail D, Ilie M, Gounon P, Rouleau M, Hofman V, Doyen J, Mari B, Shoshan-Barmatz V, Hofman P, Pouysségur J, Mazure NM.

    Cancer Res.  2012 Apr 15;72(8):2140-50.

    doi: 10.1158/0008-5472.CAN-11-3940. Epub 2012 Mar 2.

    PMID: 22389449

  • [Setting up indicators in biobanking: why  and how?].

    Hofman V, Gaziello MC, Bonnetaud C, Ilie M, Mauro V, Long E, Selva E, Gavric-Tanga V, Lassalle S, Butori C, Papin-Michaud C, Lerda N, Bordone O, Coelle C, Sabourin JC, Chabannon C, Hofman P.

    Ann Pathol. 2012 Apr;32(2):91-101.

    doi: 10.1016/j.annpat.2012.02.002.  Epub 2012 Mar 28. French.

    PMID: 22520599

  • Microbes-induced EMT at the crossroad of inflammation and cancer.

    Hofman P, Vouret-Craviari V.

    Gut Microbes. 2012 May-Jun;3(3):176-85.

    doi: 10.4161/gmic.20288. Epub 2012 May 1. Review.

    PMID: 22572828


  • Etiology of Crohn's disease: many roads lead to autophagy. J Mol Med (Berl). 2012 Sep;90(9):987-96.

    Lapaquette P, Brest P, Hofman P, Darfeuille-Michaud A.

    doi: 10.1007/s00109-012-0934-8. Epub 2012 Jul 14. Review.

    PMID: 22797958

  • Cell-type-specific control of enhancer activity by H3K9 trimethylation.


    Zhu Y, van Essen D*, Saccani S*

    Mol Cell. 2012 May 25;46(4):408-23.

    (* corresponding author)

  • Off the beaten paths: alternative and crosstalk regulation of Rho GTPases

    Boulter E, Estrach S, Garcia-Mata R, Féral CC.

    FASEB J. 2012 Feb;26(2):469-79. doi: 10.1096/fj.11-192252. Epub 2011 Oct 28. Review.


  • Pluripotent stem cell model reveals essential roles for miR-450b-5p and miR-184 in embryonic corneal lineage specification.

    Shalom-Feuerstein R, Serror L, De La Forest Divonne S, Petit I, Aberdam E, Camargo L, Damour O, Vigouroux C, Solomon A, Gaggioli C, Itskovitz-Eldor J, Ahmad S, Aberdam D.

    Stem Cells. 2012 May;30(5):898-909. 

    PMID: 22367714
  • Consequences of telomere shortening during lifespan.

    Henriques CM, Ferreira MG.

    Current opinion in cell biology. 2012; 24(6):804-8.

    PMID: 23127607
  • Reciprocal signaling between the ectoderm and a mesendodermal left-right organizer directs left-right determination in the sea urchin embryo

    Bessodes N, Haillot E, Duboc V, Röttinger E, Lahaye F, Lepage T.

    PLoS Genet. 2012;8(12):e1003121.

    PMID: 23271979

  • A framework for the establishment of a cnidarian gene regulatory network for "endomesoderm" specification: the inputs of ß-catenin/TCF signaling

    Röttinger E, Dahlin P, Martindale MQ.

    PLoS Genet. 2012;8(12):e1003164.

    PMID: 23300467

  • Adipocytes secrete leukotrienes: contribution to obesity-associated inflammation and insulin resistance in mice

    Mothe-Satney I, Filloux C, Amghar H, Pons C, Bourlier V, Galitzky J, Grimaldi PA, Féral CC, Bouloumié A, Van Obberghen E, Neels JG.

    Diabetes. 2012 Sep;61(9):2311-9. doi: 10.2337/db11-1455. Epub 2012 Jun 11.


  • Circulating tumor cells in prostate cancer: a potential surrogate marker of survival.

    Doyen J, Alix-Panabières C, Hofman P, Parks SK, Chamorey E, Naman H, Hannoun-Lévi JM.

    Crit Rev Oncol Hematol. 2012 Mar;81(3):241-56.

    doi: 10.1016/j.critrevonc.2011.05.004. Epub 2011 Jun 15. Review.

    PMID: 21680196

  • A comparative gene expression database for invertebrates

    Ormestad M, Martindale MQ, Röttinger E.

    Evodevo. 2011 Aug 24;2:17.

    PMID: 21861937

  • Strategy to find molecular signatures in a small series of rare cancers: validation for radiation-induced breast and thyroid tumors.

    Ugolin N, Ory C, Lefevre E, Benhabiles N, Hofman P, Schlumberger M, Chevillard S.

    PLoS One. 2011;6(8):e23581.

    doi: 10.1371/journal.pone.0023581. Epub 2011 Aug 11.

    PMID: 21853153

  • Can the microRNA signature distinguish between thyroid tumors of uncertain malignant potential and other well-differentiated tumors of the thyroid gland?

    Lassalle S, Hofman V, Ilie M, Bonnetaud C, Puisségur MP, Brest P, Loubatier  C, Guevara N, Bordone O, Cardinaud B, Lebrigand K, Rios G, Santini J, Franc B, Mari B, Al Ghuzlan A, Vielh P, Barbry P, Hofman P.

    Endocr Relat Cancer. 2011 Sep 13;18(5):579-94.

    doi: 10.1530/ERC-10-0283. Print 2011 Oct.

    PMID: 21778212

  • The naturally processed CD95L elicits a c-yes/calcium/PI3K-driven cell migration pathway.

    Tauzin S, Chaigne-Delalande B, Selva E, Khadra N, Daburon S, Contin-Bordes C, Blanco P, Le Seyec J, Ducret T, Counillon L, Moreau JF, Hofman P, Vacher P, Legembre P.

    PLoS Biol. 2011 Jun;9(6):e1001090.

    doi: 10.1371/journal.pbio.1001090. Epub 2011 Jun 21.

    PMID: 21713032

  • Adherent-invasive Escherichia coli induce claudin-2 expression and barrier defect in CEABAC10 mice and Crohn's disease patients.

    Denizot J, Sivignon A, Barreau F, Darcha C, Chan HF, Stanners CP, Hofman P,  Darfeuille-Michaud A, Barnich N.

    Inflamm Bowel Dis. 2012 Feb;18(2):294-304.

    doi: 10.1002/ibd.21787. Epub 2011 Jun 17.

    PMID: 21688348

  • Cytopathologic detection of circulating tumor cells using the isolation by size of epithelial tumor cell method: promises and pitfalls.

    Hofman VJ, Ilie MI, Bonnetaud C, Selva E, Long E, Molina T, Vignaud JM, Fléjou JF, Lantuejoul S, Piaton E, Butori C, Mourad N, Poudenx M, Bahadoran P, Sibon S, Guevara N, Santini J, Vénissac N, Mouroux J, Vielh P, Hofman PM.

    Am J Clin Pathol. 2011 Jan;135(1):146-56.

    doi: 10.1309/AJCP9X8OZBEIQVVI.

    PMID: 21173137.

  • Discriminating gene expression signature of radiation-induced thyroid tumors after either external exposure or internal contamination.

    Ory C, Ugolin N, Schlumberger M, Hofman P, Chevillard S.

    Genes (Basel). 2011 Dec 21;3(1):19-34.

    doi: 10.3390/genes3010019.

    PMID: 24704841

  • Senescent cells develop a PARP-1 and nuclear factor-{kappa}B-associated secretome (PNAS).

    Ohanna M, Giuliano S, Bonet C, Imbert V, Hofman V, Zangari J, Bille K, Robert C, Bressac-de Paillerets B, Hofman P, Rocchi S, Peyron JF, Lacour JP, Ballotti R, Bertolotto C.

    Genes Dev. 2011 Jun 15;25(12):1245-61.

    doi: 10.1101/gad.625811. Epub 2011 Jun 6.

    PMID: 21646373


  • MiR-129-5p is required for histone deacetylase inhibitor-induced cell death in thyroid cancer cells.

    Brest P, Lassalle S, Hofman V, Bordone O, Gavric Tanga V, Bonnetaud C, Moreilhon C, Rios G, Santini J, Barbry P, Svanborg C, Mograbi B, Mari B, Hofman P.

    Endocr Relat Cancer. 2011 Nov 14;18(6):711-9.

    doi: 10.1530/ERC-10-0257. Print 2011 Dec.

    PMID: 21946411

  • The endoplasmic reticulum stress response chaperone: Gp96, a host receptor for Crohn disease-associated adherent-invasive Escherichia coli.

    Rolhion N, Hofman P, Darfeuille-Michaud A.

    Gut Microbes. 2011 Mar-Apr;2(2):115-9. Epub 2011 Mar 1. Review.

    PMID: 21637029

  • The role of a bioresource research impact factor as an incentive to share human bioresources.

    Cambon-Thomsen A, Thorisson GA, Mabile L; BRIF Workshop Group.

    Nat Genet. 2011 Jun;43(6):503-4.

    doi: 10.1038/ng.831.

    PMID: 21614086

  • Clinical impact of cervical lymph node involvement and central neck dissection in patients with papillary thyroid carcinoma: a retrospective analysis of 368 cases.

    Bozec A, Dassonville O, Chamorey E, Poissonnet G, Sudaka A, Peyrottes I, Ettore F, Haudebourg J, Bussière F, Benisvy D, Marcy PY, Sadoul JL, Hofman P, Lassale S, Vallicioni J, Demard F, Santini J.

    Eur Arch Otorhinolaryngol. 2011 Aug;268(8):1205-1212.

    doi: 10.1007/s00405-011-1639-2. Epub 2011 May 24.

    PMID: 21607578

  • Risk predisposition for Crohn disease: a "ménage à trois" combining IRGM allele, miRNA and xenophagy.

    Brest P, Lapaquette P, Mograbi B, Darfeuille-Michaud A, Hofman P.

    Autophagy. 2011 Jul;7(7):786-7. Epub 2011 Jul 1.

    PMID: 21508684

  • Cadmium-induced autophagy in rat kidney: an early biomarker of subtoxic exposure.

    Chargui A, Zekri S, Jacquillet G, Rubera I, Ilie M, Belaid A, Duranton C, Tauc M, Hofman P, Poujeol P, El May MV, Mograbi B.

    Toxicol Sci. 2011 May;121(1):31-42.

    doi: 10.1093/toxsci/kfr031. Epub 2011 Feb 15.

    PMID: 21325019

  • A synonymous variant in IRGM alters a binding site for miR-196 and causes deregulation of IRGM-dependent xenophagy in Crohn's disease.

    Brest P, Lapaquette P, Souidi M, Lebrigand K, Cesaro A, Vouret-Craviari V, Mari B, Barbry P, Mosnier JF, Hébuterne X, Harel-Bellan A, Mograbi B, Darfeuille-Michaud A, Hofman P.

    Nat Genet. 2011 Mar;43(3):242-5.

    doi: 10.1038/ng.762. Epub 2011 Jan 30. 

    PMID: 21278745

  • Gene expression signature discriminates sporadic from post-radiotherapy-induced thyroid tumors.

    Ory C, Ugolin N, Levalois C, Lacroix L, Caillou B, Bidart JM, Schlumberger M, Diallo I, de Vathaire F, Hofman P, Santini J, Malfoy B, Chevillard S.

    Endocr Relat Cancer. 2011 Jan 19;18(1):193-206.

    doi: 10.1677/ERC-10-0205. Print 2011 Feb.

    PMID: 21148326

  • miR-483-3p controls proliferation in wounded epithelial cells.

    Bertero T, Gastaldi C, Bourget-Ponzio I, Imbert V, Loubat A, Selva E, Busca  R, Mari B, Hofman P, Barbry P, Meneguzzi G, Ponzio G, Rezzonico R.

    FASEB J. 2011 Sep;25(9):3092-105.

    doi: 10.1096/fj.10-168401. Epub 2011 Jun 15.

    PMID: 21676945

  • Trait variation in yeast is defined by population history

    Warringer J, Zörgö E, Cubillos FA, Zia A, Gjuvsland A, Simpson JT, Forsmark A, Durbin R, Omholt SW, Louis EJ, Liti G, Moses A, Blomberg A.

    PLoS Genet. 2011 Jun;7(6):e1002111. doi: 10.1371/journal.pgen.1002111.

    PMID: 21698134

  • Detection of circulating tumor cells as a prognostic factor in patients undergoing radical surgery for non-small-cell lung  carcinoma: comparison of the efficacy of the CellSearch Assay™ and the isolation  by size of epithelial tumor cell method.

    Hofman V, Ilie MI, Long E, Selva E, Bonnetaud C, Molina T, Vénissac N, Mouroux J, Vielh P, Hofman P.

    Int J Cancer. 2011 Oct 1;129(7):1651-60.

    doi: 10.1002/ijc.25819. Epub 2011 Mar 11.

    PMID: 21128227.

  • A Geographically Diverse Collection of Schizosaccharomyces pombe Isolates Shows Limited Phenotypic Variation but Extensive Karyotypic Diversity

    Brown WR, Liti G, Rosa C, James S, Roberts I, Robert V, Jolly N, Tang W, Baumann P, Green C, Schlegel K, Young J, Hirchaud F, Leek S, Thomas G, Blomberg A, Warringer J.

    G3 (Bethesda). 2011 Dec;1(7):615-26. doi: 10.1534/g3.111.001123.

    PMID: 22384373

  • The rise of yeast population genomics

    Liti G, Schacherer J.

    C R Biol. 2011 Aug-Sep;334(8-9):612-9. doi: 10.1016/j.crvi.2011.05.009.

    PMID: 21819942

  • Revealing the genetic structure of a trait by sequencing a population under selection

    Parts L, Cubillos FA, Warringer J, Jain K, Salinas F, Bumpstead SJ, Molin M, Zia A, Simpson JT, Quail MA, Moses A, Louis EJ, Durbin R, Liti G.

    Genome Res. 2011 Jul;21(7):1131-8. doi: 10.1101/gr.116731.110.

    PMID: 21422276

  • From sequence to function: Insights from natural variation in budding yeasts

    Nieduszynski CA, Liti G.

    Biochim Biophys Acta. 2011 Oct;1810(10):959-66. doi: 10.1016/j.bbagen.2011.02.004.

    PMID: 21320572

  • Assessing the complex architecture of polygenic traits in diverged yeast populations

    Cubillos FA, Billi E, Zörgö E, Parts L, Fargier P, Omholt S, Blomberg A, Warringer J, Louis EJ, Liti G.

    Mol Ecol. 2011 Apr;20(7):1401-13. doi: 10.1111/j.1365-294X.2011.05005.x.

    PMID: 21261765

  • Disruption of telomerase trafficking by TCAB1 mutation causes dyskeratosis congenita

    Zhong F, Savage SA, Shkreli M, Giri N, Jessop L, Myers T, Chen R, Alter BP, Artandi SE.

    Genes Dev. 2011 Jan 1;25(1):11-6

    PMID: 21205863


  • Reversible cell-cycle entry in adult kidney podocytes through regulated control of telomerase and Wnt signaling

    Shkreli M, Sarin KY, Pech MF, Papeta N, Chang W, Brockman SA, Cheung P, Lee E, Kuhnert F, Olson JL, Kuo CJ, Gharavi AG, D'Agati VD, Artandi SE.

    Nat Med. 2011 Dec 4;18(1):111-9

    PMID: 22138751
  • Ancestral regulatory circuits governing ectoderm patterning downstream of Nodal and BMP2/4 revealed by gene regulatory network analysis in an echinoderm

    Saudemont A, Haillot E, Mekpoh F, Bessodes N, Quirin M, Lapraz F, Duboc V, Röttinger E, Range R, Oisel A, Besnardeau L, Wincker P, Lepage T.

    PLoS Genet. 2010 Dec 23;6(12):e1001259.

    PMID: 21203442

  • Short telomeres and stem cell exhaustion model Duchenne muscular dystrophy in mdx/mTR mice

    Sacco A, Mourkioti F, Tran R, Choi J, Llewellyn M, Kraft P, Shkreli M, Delp S, Pomerantz JH, Artandi SE, Blau HM.

    Cell. 2010 Dec 23;143(7):1059-71

    PMID: 21145579


  • A feed-forward circuit controlling inducible NF-κB target gene activation by promoter histone demethylation.


    van Essen D, Zhu Y, Saccani S.

    Mol Cell. 2010 Sep 10;39(5):750-60.

  • TIN2-tethered TPP1 recruits human telomerase to telomeres in vivo.

    Abreu E, Aritonovska E, Reichenbach P, Cristofari G, Culp B, Terns RM, Lingner J, Terns MP.

    Mol Cell Biol. 2010 Jun;30(12):2971-82.

    PMID: 20404094

  • Two modes of transcriptional activation at native promoters by NF-kappaB p65.


    van Essen D, Engist B, Natoli G, Saccani S.

    PLoS Biol. 2009 Mar 31;7(3):e73. doi: 10.1371/journal.pbio.1000073.

  • Population genomics of domestic and wild yeasts

    Liti G, Carter DM, Moses AM, Warringer J, Parts L, James SA, Davey RP, Roberts IN, Burt A, Koufopanou V, Tsai IJ, Bergman CM, Bensasson D, O'Kelly MJ, van Oudenaarden A, Barton DB, Bailes E, Nguyen AN, Jones M, Quail MA, Goodhead I, Sims S, Smith F, Blomberg A, Durbin R, Louis EJ.

    Nature. 2009 Mar 19;458(7236):337-41. doi: 10.1038/nature07743.

    PMID: 19212322

  • Segregating YKU80 and TLC1 alleles underlying natural variation in telomere properties in wild yeast

    Liti G, Haricharan S, Cubillos FA, Tierney AL, Sharp S, Bertuch AA, Parts L, Bailes E, Louis EJ.

    PLoS Genet. 2009 Sep;5(9):e1000659. doi: 10.1371/journal.pgen.1000659.

    PMID: 19763176

  • Generation of a large set of genetically tractable haploid and diploid Saccharomyces strains

    Cubillos FA, Louis EJ, Liti G.

    FEMS Yeast Res. 2009 Dec;9(8):1217-25. doi: 10.1111/j.1567-1364.2009.00583.x.

    PMID: 19840116

  • Telomerase modulates Wnt signalling by association with target gene chromatin

    Park JI, Venteicher AS, Hong JY, Choi J, Jun S, Shkreli M, Chang W, Meng Z, Cheung P, Ji H, McLaughlin M, Veenstra TD, Nusse R, McCrea PD, Artandi SE.

    Nature. 2009 Jul 2;460(7251):66-72

    PMID: 19571879


  • Centralization of the deuterostome nervous system predates chordates

    Nomaksteinsky M, Röttinger E, Dufour HD, Chettouh Z, Lowe CJ, Martindale MQ, Brunet JF.

    Curr Biol. 2009 Aug 11;19(15):1264-9.

    PMID: 19559615

  • An affinity oligonucleotide displacement strategy to purify ribonucleoprotein complexes applied to human telomerase.

    Kurth I, Cristofari G, Lingner J.

    Methods Mol Biol. 2008;488:9-22.

    PMID: 18982281
  • FGF signals guide migration of mesenchymal cells, control skeletal morphogenesis and regulate gastrulation during sea urchin development

    Röttinger E, Saudemont A, Duboc V, Besnardeau L, McClay D, Lepage T.

    Development. 2008 Jan;135(2):353-65. Epub 2007 Dec 12.

    PMID: 18077587

  • Telomerase unplugged.

    Cristofari G, Sikora K, Lingner J.

    ACS Chem Biol. 2007 Mar 20;2(3):155-8. 

    PMID: 17373762&

  • Reevaluation of telomerase inhibition by quadruplex ligands and their mechanisms of action.

    De Cian A, Cristofari G, Reichenbach P, De Lemos E, Monchaud D, Teulade-Fichou MP, Shin-Ya K, Lacroix L, Lingner J, Mergny JL.

    Proc Natl Acad Sci U S A. 2007 Oct 30;104(44):17347-52. 

    PMID: 17954919
  • Involvement of the oncoprotein c-Myc in viral telomerase RNA gene regulation during Marek's disease virus-induced lymphomagenesis

    Shkreli M, Dambrine G, Soubieux D, Kut E, Rasschaert D.

    J Virol. 2007 May;81(9):4848-57

    PMID: 17314164

  • Low- to high-throughput analysis of telomerase modulators with Telospot.

    Cristofari G, Reichenbach P, Regamey PO, Banfi D, Chambon M, Turcatti G, Lingner J.

    Nat Methods. 2007 Oct;4(10):851-3.

    PMID: 17893679
  • Human telomerase RNA accumulation in Cajal bodies facilitates telomerase recruitment to telomeres and telomere elongation.

    Cristofari G, Adolf E, Reichenbach P, Sikora K, Terns RM, Terns MP, Lingner J.

    Mol Cell. 2007 Sep 21;27(6):882-9.

    PMID: 17889662
  • RTK and TGF-beta signaling pathways genes in the sea urchin genome

    Lapraz F, Röttinger E, Duboc V, Range R, Duloquin L, Walton K, Wu SY, Bradham C, Loza MA, Hibino T, Wilson K, Poustka A, McClay D, Angerer L, Gache C, Lepage T.

    Dev Biol. 2006 Dec 1;300(1):132-52.

    PMID: 17084834

  • The genome of the sea urchin Strongylocentrotus purpuratus

    Sodergren E, Weinstock GM, Davidson EH, & Sea Urchin Genome Sequencing Consortium.

    Science. 2006 Nov 10;314(5801):941-52. 

    PMID: 17095691

  • Sequence diversity, reproductive isolation and species concepts in Saccharomyces

    Liti G, Barton DB, Louis EJ.

    Genetics. 2006 Oct;174(2):839-50. Epub 2006 Sep 1.

    PMID: 16951060

  • Telomere length homeostasis requires that telomerase levels are limiting.

    Cristofari G, Lingner J.

    EMBO J. 2006 Feb 8;25(3):565-74.

    PMID: 16424902

  • Expression pattern of three putative RNA-binding proteins during early development of the sea urchin Paracentrotus lividus

    Röttinger E, Besnardeau L, Lepage T.

    Gene Expr Patterns. 2006 Oct;6(8):864-72.

    PMID: 17061352

  • Nemo-like kinase (NLK) acts downstream of Notch/Delta signalling to downregulate TCF during mesoderm induction in the sea urchin embryo

    Röttinger E, Croce J, Lhomond G, Besnardeau L, Gache C, Lepage T.

    Development. 2006 Nov;133(21):4341-53.

    PMID: 17038519


  • Left-right asymmetry in the sea urchin embryo is regulated by nodal signaling on the right side

    Duboc V, Röttinger E, Lapraz F, Besnardeau L, Lepage T.

    Dev Cell. 2005 Jul;9(1):147-58.

    PMID: 15992548

  • Yeast evolution and comparative genomics

    Liti G, Louis EJ.

    Annu Rev Microbiol. 2005;59:135-53.

    PMID: 15877535

  • Inferences of evolutionary relationships from a population survey of LTR-retrotransposons and telomeric-associated sequences in the Saccharomyces sensu stricto complex

    Liti G, Peruffo A, James SA, Roberts IN, Louis EJ.

    Yeast. 2005 Feb;22(3):177-92.

    PMID: 15704235

  • The hepatitis C virus Core protein is a potent nucleic acid chaperone that directs dimerization of the viral (+) strand RNA in vitro.

    Cristofari G, Ivanyi-Nagy R, Gabus C, Boulant S, Lavergne JP, Penin F, Darlix JL.

    Nucleic Acids Res. 2004 May 11;32(8):2623-31.

    PMID: 15141033

  • A Raf/MEK/ERK signaling pathway is required for development of the sea urchin embryo micromere lineage through phosphorylation of the transcription factor Ets

    Röttinger E, Besnardeau L, Lepage T.

    Development. 2004 Mar;131(5):1075-87.

    PMID: 14973284

  • Analysis of a Ty1-less variant of Saccharomyces paradoxus: the gain and loss of Ty1 elements

    Moore SP, Liti G, Stefanisko KM, Nyswaner KM, Chang C, Louis EJ, Garfinkel DJ.

    Yeast. 2004 Jun;21(8):649-60.

    PMID: 15197730

  • Nodal and BMP2/4 signaling organizes the oral-aboral axis of the sea urchin embryo

    Duboc V, Röttinger E, Besnardeau L, Lepage T.

    Dev Cell. 2004 Mar;6(3):397-410.

    PMID: 15030762

  • Insertion of a foreign sequence on capsid surface loops of human papillomavirus type 16 virus-like particles reduces their capacity to induce neutralizing antibodies and delineates a conformational neutralizing epitope

    Sadeyen JR, Tourne S, Shkreli M, Sizaret PY, Coursaget P.

    Virology. 2003 Apr 25;309(1):32-40

    PMID: 12726724

  • Fingering the ends: how to make new telomeres.

    Cristofari G, Lingner J.

    Cell. 2003 May 30;113(5):552-4. Review.

    PMID: 12787493

  • NEJ1 prevents NHEJ-dependent telomere fusions in yeast without telomerase

    Liti G, Louis EJ.

    Mol Cell. 2003 May;11(5):1373-8.

    PMID: 12769859

  • The ubiquitous nature of RNA chaperone proteins.

    Cristofari G, Darlix JL.

    Prog Nucleic Acid Res Mol Biol. 2002;72:223-68. Review.

    PMID: 12206453
  • A 5'-3' long-range interaction in Ty1 RNA controls its reverse transcription and retrotransposition.

    Cristofari G, Bampi C, Wilhelm M, Wilhelm FX, Darlix JL.

    EMBO J. 2002 Aug 15;21(16):4368-79.

    PMID: 12169639
  • Non-radioactive dot-blot DNA reassociation for unequivocal yeast identification

    Cardinali G, Liti G, Martini A.

    Int J Syst Evol Microbiol. 2000 Mar;50 Pt 2:931-6.

    PMID: 10758906

  • The GAG-like protein of the yeast Ty1 retrotransposon contains a nucleic acid chaperone domain analogous to retroviral nucleocapsid proteins.

    Cristofari G, Ficheux D, Darlix JL.

    J Biol Chem. 2000 Jun 23;275(25):19210-7.

    PMID: 10766747
  • Nucleocapsid protein of human immunodeficiency virus as a model protein with chaperoning functions and as a target for antiviral drugs.

    Darlix JL, Cristofari G, Rau M, Péchoux C, Berthoux L, Roques B.

    Adv Pharmacol. 2000;48:345-72. Review.

    PMID: 10987096
  • Characterization of active reverse transcriptase and nucleoprotein complexes of the yeast retrotransposon Ty3 in vitro.

    Cristofari G, Gabus C, Ficheux D, Bona M, Le Grice SF, Darlix JL.

    J Biol Chem. 1999 Dec 17;274(51):36643-8.

    PMID: 10593967