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IRCAN's scientific goals

When the data on epidemiology and pathophysiology are analyzed, aging is usually perceived as a process that results from the combined influence of constitutional or so-called « genetic » factors, life-style associated factors and external events. Gerontobiology looks into all the specific medical and biological features of aging on the scale of the human body and develops concepts such as « harmonious » aging, « vulnerable » and « hypercatabolic » states, illustrating the highly heterogeneous characteristics of the aging process. The extreme heterogeneity of aging can be illustrated for a given age by a residual life-expectancy that varies considerably from one individual to another and by the onset, or not, of degenerative disorders, especially cardiovascular and neurological diseases, bone and joint disorders, diabetes and also neoplasms, pathologies in which constitutional determinants and other external factors play a role as they do in aging. [Read more...]



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